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Dietary Supplements: A Framework for Evaluating Safety (2005)
Institute of Medicine (IOM)

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. "Appendix M: Biographical Sketches of Commitee Members." Dietary Supplements: A Framework for Evaluating Safety. Washington, DC: The National Academies Press, 2005.

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Dietary Supplements: A Framework for Evaluating Safety

Norman R. Farnsworth, Ph.D., is a distinguished university professor, research professor of pharmacognosy, director of the Pharmacognosy Graduate Program, and the director of the Program for Collaborative Research in the Pharmaceutical Sciences at the University of Illinois at Chicago (UIC). Dr. Farnsworth also serves as Director of the UIC/National Institutes of Health (NIH) Dietary Supplements Research Center at UIC. He is credited with designing a worldwide computer database, NAPRALERT, that compiles scientific literature on the safety and efficacy of herbal medicines, plants, marine organisms, and fungi. Dr. Farnsworth is also director of the World Health Organization (WHO) Collaborating Center for Traditional Medicine; using the NAPRALERT database, he has lead WHO’s publication of numerous monographs reviewing traditional medicinals. He is a member of Health Canada’s Expert Advisory Committee on Natural Health Products and served on the U.S. Commission on Dietary Supplement Labels authorized by the Dietary Supplement Health and Education Act of 1994. Dr. Farnsworth serves on the Scientific Advisory Board of the Herb Research Foundation, the Board of Trustees of the American Botanical Council, and the editorial advisory board of several peer-reviewed journals and Herbalgram. He has authored a number of publications about botanicals, including Botanical Dietary Supplements Quality, Safety, and Efficacy. His research interests include analysis of chemical and biological data on natural products, and isolation, identification, and structure elucidation of biologically active plant constituents.

Ted Gansler, M.D., M.B.A., is director of Medical Information Strategy at the American Cancer Society (ACS) and editor of the ACS publication CA: A Cancer Journal for Clinicians. At ACS, Dr. Gansler is responsible for assuring the accuracy of printed and electronic information products for patients, the general public, and health professionals. He is a graduate of Duke University, University of Pittsburgh School of Medicine, and Georgia State University School of Business Administration, and he completed a pathology residency and cytopathology fellowship at the University of Pennsylvania. Until recently, Dr. Gansler practiced cytopathology and surgical pathology at Emory University, and is currently an adjunct associate professor of pathology at Emory.

James E. Gibson, Ph.D., is a research professor of pharmacology and toxicology with the Brody School of Medicine at East Carolina University. Prior to his current appointment, Dr. Gibson was with Dow Agro Sciences, a world leader in the development and manufacture of chemicals and biotechnology for agriculture; former positions include global director for Regulatory, Toxicology and Environmental Affairs for Dowlanco and director of Toxicology Affairs for the Dow Chemical Company. In addition to teaching and establishing a program in toxicology, Dr. Gibson is currently pursuing research in developing and evaluating innovative in vitro

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483
Front Matter (R1-R20)
Executive Summary (1-18)
1 Introduction and Background (19-42)
2 Approaches Used by Others and Existing Safety Frameworks (43-84)
3 The Framework (85-125)
4 Categories of Scientific Evidence--Human Information and Data (126-155)
5 Categories of Scientific Evidence--Animal Data (156-174)
6 Categories of Scientific Evidence--Information About Related Substances (175-216)
7 Categories of Scientific Evidence--In Vitro Data (217-234)
8 Interactions (235-246)
9 Vulnerable Groups and Prevalance of Use (247-252)
10 Scientific Principles for Integrating and Evaluating the Available Data (253-268)
11 Applying the Framework: Case Studies Using the Prototype Safety Monographs (269-291)
12 Factors Influencing Use of the Safety Framework (292-296)
13 Findings and Recommendations (297-306)
Appendix A: Existing Frameworks or Systems for Evaluating the Safety of Other Substances (307-315)
Appendix B: Scope of Work and Comments to Initial July 2002 Framework (316-321)
Appendix C: Plant Family Information (322-355)
Appendix D: Chaparral: Prototype Monograph Summary (356-362)
Appendix E: Glucosamine: Prototype Monograph Summary (363-366)
Appendix F: Melatonin: Prototype Monograph Summary (367-371)
Appendix G: Chromium Picolinate: Prototype Monograph Summary (372-375)
Appendix H: Saw Palmetto: Prototype Monograph Summary (376-379)
Appendix I: Shark Cartilage: Prototype Monograph Summary (380-384)
Appendix J: Prototype Focused Monograph: Review of Liver-Related Risks for Chaparral (385-449)
Appendix K: Protoype Focused Monograph: Review of Anti-Androgenic Risks of Saw Palmetto Ingestion by Women (450-477)
Appendix L: Acknowledgements (478-480)
Appendix M: Biographical Sketches of Commitee Members (481-488)
Index (489-506)