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Dietary Supplements: A Framework for Evaluating Safety (2005)
Institute of Medicine (IOM)

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. "Appendix M: Biographical Sketches of Commitee Members." Dietary Supplements: A Framework for Evaluating Safety. Washington, DC: The National Academies Press, 2005.

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Dietary Supplements: A Framework for Evaluating Safety

Elizabeth Jeffery, Ph.D., serves as professor of nutritional toxicology at the Department of Food Science and Human Nutrition, the Division of Nutritional Sciences and the Department of Pharmacology at the University of Illinois, Urbana-Champaign. She has a Ph.D. in biochemistry from the University of London (U.K.) and teaches and conducts research in the area of safety and efficacy of functional foods and dietary supplements. Dr. Jeffery investigates the potential for soy to affect bone health and for broccoli and other crucifers to prevent cancer. Dr. Jeffery is a past editor of the American Society for Pharmacology and Experimental Therapeutics Drug Metabolism Newsletter and past associate editor of Toxicology and Applied Pharmacology. She is presently chair of the Bioactive Components Research Interest Section of the American Society for Nutritional Sciences, chair of the Toxicology Division of the American Society for Pharmacology and Experimental Therapeutics, and secretary/treasurer of the Food Safety Specialty Section of the Society of Toxicology.

Loren D. Koller, D.V.M., Ph.D., is an independent consultant with over 30 years of experience as a researcher in the areas of pathology, toxicology, immunology, carcinogenesis, and nutrition. Dr. Koller’s past employment has been with National Institute of Environmental Health Sciences, Oregon State University, and University of Idaho. He has published in numerous refereed journals in his areas of interest, and served on several editorial boards, grant review panels, and as a consultant to government, business, and private firms. Dr. Koller has been engaged in biomedical environmental research relating to health effects in humans most of his career, including while serving as a dean in the College of Veterinary Medicine at Oregon State University for 10 years. He has experience and knowledge in agriculture, biomedicine, and environmental health, with an appreciation and sensitivity of the issues involved in developing federal regulations. He has served on committees for the National Cancer Institute, Agency for Toxic Substance and Disease Registry, Centers for Disease Control and Prevention, and U.S. Army, and on the National Advisory Committee to Establish Acute Exposure Guidelines for Hazardous Substances. Dr. Koller is a fellow of the Academy of Toxicological Science. He has cotaught veterinary microscopic anatomy, pathology, advanced clinical and diagnostic toxicology, tumor pathology, principles of toxicology, environmental and comparative toxicology, and target organ toxicology.

Joseph Lau, M.D., is a professor of medicine at the Tufts University School of Medicine and professor of clinical research at the Sackler School of Graduate Biomedical Sciences at Tufts University. He is also director of the Boston branch of the U.S. Cochrane Center and director of one of the 13 Agency for Health Care Research and Quality designated Evidence-based Practice Centers, located at the Tufts-New England Medical Center in Boston. Dr. Lau also directs the evidence review team of the National

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485
Front Matter (R1-R20)
Executive Summary (1-18)
1 Introduction and Background (19-42)
2 Approaches Used by Others and Existing Safety Frameworks (43-84)
3 The Framework (85-125)
4 Categories of Scientific Evidence--Human Information and Data (126-155)
5 Categories of Scientific Evidence--Animal Data (156-174)
6 Categories of Scientific Evidence--Information About Related Substances (175-216)
7 Categories of Scientific Evidence--In Vitro Data (217-234)
8 Interactions (235-246)
9 Vulnerable Groups and Prevalance of Use (247-252)
10 Scientific Principles for Integrating and Evaluating the Available Data (253-268)
11 Applying the Framework: Case Studies Using the Prototype Safety Monographs (269-291)
12 Factors Influencing Use of the Safety Framework (292-296)
13 Findings and Recommendations (297-306)
Appendix A: Existing Frameworks or Systems for Evaluating the Safety of Other Substances (307-315)
Appendix B: Scope of Work and Comments to Initial July 2002 Framework (316-321)
Appendix C: Plant Family Information (322-355)
Appendix D: Chaparral: Prototype Monograph Summary (356-362)
Appendix E: Glucosamine: Prototype Monograph Summary (363-366)
Appendix F: Melatonin: Prototype Monograph Summary (367-371)
Appendix G: Chromium Picolinate: Prototype Monograph Summary (372-375)
Appendix H: Saw Palmetto: Prototype Monograph Summary (376-379)
Appendix I: Shark Cartilage: Prototype Monograph Summary (380-384)
Appendix J: Prototype Focused Monograph: Review of Liver-Related Risks for Chaparral (385-449)
Appendix K: Protoype Focused Monograph: Review of Anti-Androgenic Risks of Saw Palmetto Ingestion by Women (450-477)
Appendix L: Acknowledgements (478-480)
Appendix M: Biographical Sketches of Commitee Members (481-488)
Index (489-506)