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products sold in the United States
Sponsorship by trade association organization
Starting assumptions of safety; lack of information appears to be interpreted as safety
Preclinical safety data section may be useful for individual botanicals
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of supplements that are covered; describes a wide range of dietary
A useful cross-reference to brand names is included
The continuum of safety classifications considered is helpful, as is the attention paid to formulation, plant part, and species
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Resource
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Considerations
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Natural Standard (Natural Standard, 2003) (Reviewed Black Cohosh)
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Physican’s Desk Reference (PDR) for Herbal Medicines (Medical Economics, 1998, 2000)
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Type of organization responsible for resource
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For-profit, not supported by any interest group, professional organization, or pharmaceutical manufacturer
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For-profit organization
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Substances reviewed
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Covers alternative therapies and complementary medicines, including nutrient and nonnutrient dietary supplements
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Over 700 botanicals
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Product/endpoint
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Online monograph
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Book of brief monographs
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Focus on safety/risk
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Safety and efficacy are considered
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Both safety and efficacy are considered
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Reliance on primary data
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Mostly primary sources, some abstracts, including foreign language articles
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Primary sources are cited, including foreign language sources
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Use of nonhuman data
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Mostly human data, some in vitro data and a limited number of animal studies are considered
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Mostly human data; however, some animal and in vitro data are considered
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Description of limitations
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Limitations are described
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Limitations are somewhat described
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Description of literature search strategy
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Described thoroughly
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Search strategy is not described; many monographs appear to be based upon the Commission E translation
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