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Focus on a particular standardized product and discussion of preparation impact on safety

Defines the medicinal plant and describes compounds to standardize a product; adverse reaction description discusses preparation

Description of consumption levels considered

Dose is specified in relation to adverse effects; although one monograph only states that “large doses may…,” many specify how much was associated with the adverse reaction

Consideration of data from non-oral routes of exposure

Non-oral data are referred to in some sections, but it is not clear if these data were considered as possibly relevant

Discussion of biological activity or possible mechanism of action

Discussed

Discussion of specific groups within the general population, if appropriate

Pregnancy, lactation, and children are considered

Interaction with other interventions

Interactions with drugs are mentioned, if known; many entries say “None reported”

Other comments and considerations for using this resource

The section on medicinal uses is divided into three parts: Uses Supported by Clinical Data; Uses Described in Traditional Medical Systems, and Uses Described in Folklore; thus, may be a good resource for historic information

 

Some of the safety data references the German Commission E

 

Useful in that the standardized product is carefully defined and adverse reactions are viewed in this context

 

Additional safety concerns may arise well after the review was prepared, due to the length of time it takes to get agreement on a monograph and print it

a This question could not be answered due to limitations in the analysis or lack of description in the available material.



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