1. A standing oversight committee should be established with the participation of ex-astronauts, the public, scientists of various disciplines, and independent external reviewers. The expertise needed by the oversight committee includes such areas as biostatistics, environmental health, clinical medicine, radiation biology, neurology, endocrinology, and cardiology. Principal activities of such an oversight committee should be review of the methods used to acquire and analyze the data, surveillance of the data set for unexpected events, and evaluation of plans for reacting to these events. In addition, this oversight committee should set up procedures for site review of the performance of the study analogous to that performed by clinical research organizations.

  2. At least one ex-astronaut and one or more non-NASA biomedical scientists should be added to the existing LSAH Executive Committee.

  3. Additional professionals (e.g., epidemiologist) and staff should be hired as necessary to keep the database current and meet the new review and reporting requirements described above.

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