Dluhy et al., 1972

8 women, 2 men, crossover

5 subjects, 6–7 d, 0.23 g (10 mmol) sodium (Na)/d

5 subjects, 3 d, 4.6 g (200 mmol) Na/d

1.6 (40)

7.8 (200)

1.6 (40)

7.8 (200)

4.1 ± 0.1^b

4.3 ± 0.1^b

4.0 ± 0.1^b

4.2 ± 0.1^b

Zoccali et al., 1985

5-d crossover, 10 men

3.0 (76)

6.9 (176)

3.9 ± 0.1^b

4.3 ± 0.1^b

Hene et al., 1986

18-d parallel, 6 men

3.1 (80)

11.7 (300)

4.26 ± 0.28^b

4.39 ± 0.32^b

Witzgall and Behr, 1986

6 d on high K diet, 16 men

2.3 g (60)

10.1 g (260)

4.2 ± 0.3^b

4.6 ± 0.3^c

Grimm et al., 1990

2.2 yr supplement/placebo intervention, 287 men, 45–68 yr, baseline urinary K = 2.2 g/d

+ 3.8 (96)

+ 0

4.2^b

4.5^c

The difference averaged 0.26 mmol/L over the 2-yr period

Rabelink et al., 1990

20 d, 6 men

3.9 (100)

15.6 (400)

3.75 ± 0.16^b

4.22 ± 0.12^b

Clinkingbeard et al., 1991

3-d crossover, 8 men

0.39 (10)

7.8 (200)

3.8 ± 0.1^b

4.3 ± 0.2^c

Deriaz et al., 1991

5-d crossover, 8 men

2.7 (69)

6.4 (163)

4.1 ± 0.2^b

3.8 ± 0.1^c

Valdes et al., 1991

4-wk crossover, 24 men and women, provided placebo or supplement

+ 0

+ 2.5 (64)

3.8 ± 0.1^b

4.1 ± 0.1^c

Smith et al., 1992

4-d crossover, 22 men and women

2.7 (70)

4.7 (120)

3.9 ± 0.1^b

4.3 ± 0.1^c

Sebastian et al., 1994

18 d, 18 postmenopausal women

2.3 (60)

+ 4.7 (120)

3.9 ± 0.15^b

4.0 ± 0.2^b

Morris et al., 1999b

38 men, parallel

+ 1.17 (30)

4.7 (120)

3.7 ± 0.2^b

4.0 ± 0.2^c

Coruzzi et al., 2001

10-d isocaloric crossover, 8 men, 3 women

0.70 (18)

3.1 (80)

3.2 ± 0.1 (standard error)^b

4.1 ± 0.05^c