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Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate (2005)
Food and Nutrition Board (FNB)

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. "5 Potassium." Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate. Washington, DC: The National Academies Press, 2005.

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Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate

TABLE 5-5 Clinical Trials on the Effects of Potassium Supplements on Blood Pressure in Hypertensive Individuals in Order of Increasing Duration of Intervention

Reference

Subjects

Study Design

Potassium Intake,b g/d (mmol/d)

Smith et al., 1992a

12 men

9 women

4-d crossover

4.6 g (200 mmol) Na

Placebo

4.7 (120) KCl

Krishna and Kapoor, 1991

10 men

2 women

10-d parallel; K restriction

2.8 g (120 mmol) Na

3.8 (96) [80 mmol KCl supplement]

0.62 (16) diet

Zoccali et al., 1985a

10 men

9 women

2-wk crossover

Placebo

3.9 (100) KCl supplement

MacGregor et al., 1982a

12 men

11 women

4-wk crossover

Placebo

2.5 (64) KCl supplement

Richards et al., 1984a

8 men

4 women

4- to 6-wk crossover; 4.1g (180 mmol) Na

2.3 (60)

7.8 (200)

Smith et al., 1985a

11 men

9 women

4-wk crossover; 1.6 g (70 mmol) Na

Placebo

2.5 (64) KCl supplement

Valdes et al., 1991a

13 men

11 women

4-wk crossover

Placebo

2.5 (64) KCl supplement

Fotherby and Potter, 1992a

5 men

13 women

4-wk crossover

Placebo

2.3 (60) KCl supplement

Kaplan et al., 1985a

6 men

10 women

6-wk crossover

Placebo

2.3 (60) KCl supplement

Matlou et al., 1986a

32 women

6-wk crossover

Placebo

2.5 (65) KCl supplement

Grobbee et al., 1987a

34 men

6 women

6-wk crossover

Placebo

2.8 (72) KCl supplement

Svetkey et al., 1987a

75 men

26 women

8-wk parallel

Placebo

4.7 (120) KCl supplement

Patki et al., 1990a

8 men

29 women

8-wk crossover

Placebo

2.3 (60) KCl supplement

Page
208
Front Matter (R1-R20)
Summary (1-20)
1 Introduction to Dietary Reference Intakes (21-36)
2 Overview and Methods (37-49)
3 A Model for the Development of Tolerable Upper Intake Levels (50-72)
4 Water (73-185)
5 Potassium (186-268)
6 Sodium and Chloride (269-423)
7 Sulfate (424-448)
8 Applications of Dietary Reference Intakes for Electrolytes and Water (449-464)
9 A Research Agenda (465-470)
Appendix A: Glossary and Acronyms (471-476)
Appendix B: Origin and Framework of the Development of Dietary Reference Intakes (477-484)
Appendix C: Predictions of Daily Water and Sodium Requirements (485-493)
Appendix D: U.S. Dietary Intake Data from the Third National Health and Nutrition Examination Survey, 1988–1994 (494-517)
Appendix E: U.S. Dietary Intake Data for Water and Weaning Foods from the Continuing Survey of Food Intakes by Individuals, 1994–1996, 1998 (518-526)
Appendix F: Canadian Dietary Intake Data for Adults from Ten Provinces, 1990–1997 (527-533)
Appendix G: U.S. Water Intake and Serum Osmolality Data from the Third National Health and Nutrition Examination Survey, 1988–1994 (534-536)
Appendix H: U.S. Total Water Intake Data by Frequency of Leisure Time Activity from the Third National Health and Nutrition Examination Survey, 1988–1994 (537-545)
Appendix I: Dose-Response Effects of Sodium Intake on Blood Pressure (546-557)
Appendix J: Serum Electrolyte Concentrations NHANES III, 1988-94 (558-563)
Appendix K: Options for Dealing with Uncertainties (564-568)
Appendix L: Acknowledgments (569-571)
Appendix M: Biographical Sketches of Panel Members (572-576)
Index (577-618)