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Dietary Reference Intakes for Water, Potassium, Sodium, Chloride, and Sulfate
TABLE 5-7 Epidemiological Studies on the Effect of Potassium Intake on Bone Mineral Density (BMD)
Reference
Study Design
Effect
Findings
New et al., 1997
Cross-sectional
944 women
+
Potassium intake was significantly (p < 0.05) correlated with BMD for lumbar spine, femoral neck, trochanter, and Ward’s area in premenopausal women
Tucker et al., 1999
Cross-sectional and longitudinal
907 men and women
+
Potassium intake was significantly (p < 0.05) associated with BMD for the femoral neck, trochanter, Ward’s area, and radius in men (cross-sectional)
In women potassium intake was significantly (p < 0.05) associated with bone mineral density for the trochanter, Ward’s area, and radius (cross-sectional)
In a 4-yr analysis of change in BMD, potassium intake was significantly (p < 0.05) associated with less decline in BMD for femoral neck and trochanter in men
New et al., 2000
Cross-sectional
62 women
+
Potassium intake was significantly (p < 0.01) associated with higher total bone mass (p < 0.05 to p < 0.005)
Potassium intake was significantly (p < 0.02) and negatively associated with pyridinoline excretion and deoxypyridinoline excretion
Jones et al., 2001
Cross-sectional
330 children
+
Significant (p < 0.001) association between urinary potassium, femoral neck, lumbar spine, and total body BMD in prepubertal children
Macdonald et al., 2004
Longitudinal
891 women
+
Significant (p < 0.05) and positive correlation between potassium intake and femoral neck BMD in premenopausal and perimenopausal women