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Urinary Potassium (mmol/24 h)

Effectsa

50 ± 12

233 ± 45

Serum K within normal limits but 10% higher (p < 0.05) with K load

≈ 60

↑ Plasma K (p < 0.01) (from 4.3 to 4.6 mmol/L)

↓ SBP (p < 0.01); ↓ DBP (p < 0.01)

≈ 220

↑ Plasma renin in 13 of 16 subjects; no adverse effects identified

82

With high K diet, ↑ plasma K (p < 0.05); plasma renin and aldosterone, while increased significantly (p < 0.01) after

385

2 d, were back to baseline levels by 20 d

50

119

Serum K was within normal limits

 

Fasting plasma aldosterone levels ↑ with increased K regardless of Na intake; no other effects noted

59

Serum K was 10% higher (p < 0.05) on high K diet, but still within normal range

161

No other changes noted

58

139

4 patients withdrew from the study: 1 due to diarrhea from the K supplement; 1 due to ↑ BP when receiving placebo; 2 due to taste of K supplement



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