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Suggested Citation:"Appendix A: Agenda." National Research Council. 2004. Promise and Challenges in Systems Microbiology: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/10934.
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Page 29
Suggested Citation:"Appendix A: Agenda." National Research Council. 2004. Promise and Challenges in Systems Microbiology: Workshop Summary. Washington, DC: The National Academies Press. doi: 10.17226/10934.
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Page 30

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Appendix A Progress and Promise in Systems Microbiology Agenda Date: August 19, 2003 Location: The National Academies Keck Building, Room 205 500 Fifth Street NW Washington, DC 8:30 - 8:45 Welcome and Introductions · Introductions Evonne Tang · Format of workshop John Doyle Case Study 1: Geobacter 8:45 - 9:15 Introductory talk on Geobacter Derek Loviey 9:15 - 9:45 Definition of a system Derek Loviey 9:45 -10:15 Data availability and high Mike Savageau throughput techniques for discovery and hypothesis driven science 10:15 - 10:45 Break 10:45 - 11:15 Modeling John Doyle Case Study 2: Termite hindgut 11:15 - 11:45 Introductory talk on termite /area Leadbetter hindgut 11:45 - 1:00 p.m. Lunch 29

30 APPENDIX A 1:00 - 1:30 Definition of a system Lyle Whyte 1:30 - 2:00 Data availability and high Awn Hasting throughput techniques for discovery and hypothesis driven science 2:00 - 2:30 Modeling Lyle Whyte 2:30 - 3:00 Break 3:00 - 3:30 Comparison between systems Michael Savageau approaches on single- and multiorganism systems 3:30 - 4:00 Integration of disciplines John Doyle 4:00 - 4:30 Education and training Awn Hastings 4:30 - 4:40 Wrap-up John Doyle 4:40 Adjourn for day

Next: Appendix B: Participant Biographies »
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 Promise and Challenges in Systems Microbiology: Workshop Summary
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Microbiologists have become interested in applying “systems biology” to understand and harness complex biological processes in microbial communities. A systems approach, which attempts to use comparative, high-throughput assays, and mathematical or computational models, has been used to generate a picture of system-wide activity that can yield insight into processes operating within a single cell. But the concept of integrating advances in genomics, proteomics, and metabolomics and incorporating them into mathematical models can also be applied to microbial ecosystems, which typically occur in consortia of related and unrelated organisms. Research on microbial communities using a system-based approach could provide a broader perspective on controls on biological processes and how they operate in and among microorganisms.

The National Academies of Sciences, Engineering, and Medicine held a workshop on “Progress and Promises of Systems Microbiology” in August 2003, with the intent of providing a forum for discussion of the tools, technology, and programs that are needed to advance the study of microorganisms through a systems approach. Participants also discussed ways to encourage collaboration among scientists of different disciplines. This report summarizes the presentations and discussions from the workshop.

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