pediatrics at Children’s Memorial Hospital in Chicago, he began studies of the mechanism of retroviral integration as a postdoctoral fellow at the University of California, San Francisco, working with J. Michael Bishop and Harold Varmus. Dr. Brown is a member of the National Academy of Sciences. Dr. Brown’s current research uses DNA microarrays and other “genomic” approaches to explore a wide range of fundamental questions in gene regulation, cell biology, physiology, development, and medicine. For the past several years he has been working to promote open, unrestricted access to scientific and scholarly publications. He is a cofounder and codirector of the Public Library of Science, a nonprofit, open-access scientific publisher.

Brian Crawford is vice president and publishing director for Global Life and Medical Sciences within the Scientific, Technical, and Medical (STM) publishing operations of John Wiley & Sons, Inc. He holds overall responsibility for coordinating the strategic development and ongoing editorial management of Wiley’s international Life and Medical Sciences publishing. Experienced in subscription journal, book, and new media publishing, Dr. Crawford has spent nearly two decades within the commercial STM information industry, most recently having served in several management roles at Wiley. Before joining Wiley, he held the position of vice president and editor with Alan R. Liss, Inc. (1988-1989), a privately held book and journal publishing firm that merged to become the wholly owned Wiley-Liss, Inc. subsidiary. Mr. Crawford began his publishing career in 1985 as an acquisitions editor within the Journals Publishing Division of Academic Press, Inc. (at that time a part of Harcourt Brace Jovanovich; now a part of Reed Elsevier). Prior to entering scientific publishing, Dr. Crawford was active in both scientific research and teaching. He had the distinction of being the first biologist to be appointed as a J. Robert Oppenheimer Fellow of the Los Alamos National Laboratory, where he was a member of the scientific research staff within the Genetics Group of the Life Sciences Division from 1981-1984, and helped to launch the Department of Energy (DOE)-sponsored human genome project. He received his Ph.D. in the biochemical and biophysical sciences at the Johns Hopkins University School of Public Health, specializing in cellular and molecular aspects of cancer genetics, under sponsorship from the National Cancer Institute. He received his B.S. cum laude in chemistry from the University of Maryland at College Park. Dr. Crawford is a member of the Board of Directors of the American Medical Publishers Association (AMPA; president-elect in 2002-2003) and the Executive Council of the Professional and Scholarly Publishing Division of the Association of American Publishers (PSP/AAP; 2001-present).

James J. Duderstadt is president emeritus and University Professor of Science and Engineering at the University of Michigan. He received his B.Eng. in electrical engineering from Yale University and his Ph.D. in engineering science and physics from the California Institute of Technology. Dr. Duderstadt joined the faculty of the University of Michigan in 1968 as professor of nuclear engineering. He became dean of the College of Engineering in 1981 and provost and vice president for academic affairs in 1986. He was appointed president of the university in 1988 and served in this role until July 1996. He currently holds a university-wide faculty appointment. Dr. Duderstadt’s teaching and research interests have spanned a wide range of subjects in science, mathematics, and engineering, including work in areas such as nuclear energy, lasers, computers, science policy, and higher education. During his career, Dr. Duderstadt has received numerous awards for his research, teaching, and service activities, including the National Medal of Technology for exemplary service to the nation. Dr. Duderstadt has served on and chaired numerous public and private boards, including the National Science Board and the National Academy of Engineering. He also serves as a director of Unisys and CMS Energy. He currently chairs several major national study commissions in areas including federal research policy, higher education, information technology, and nuclear energy.

Joseph J. Esposito is president and CEO of SRI Consulting, the leading publisher of syndicated research for the global chemical industry. Over the course of his career, Mr. Esposito has been associated with various publishers in all segments of the industry and was involved from an early time with new media publishing. He has served as an executive at Simon & Schuster and Random House, as president of Merriam-Webster, and CEO of Encyclopaedia Britannica, where he was responsible for the launch of the first Internet service of its kind. Mr. Esposito has also worked extensively in the technology industry as a consultant, with such clients as Microsoft and Hewlett-Packard, and formerly ran the Internet communications company Tribal Voice. His primary area of concentration is the development of strategy and business models for the dissemination of digital content. He has participated in numerous trade

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