TABLE 6-2 Severe Manifestations of P. falciparum Malaria in Adults and Childrena

Prognostic Valueb

 

Frequencyb

Children

Adults

 

Children

Adults

Clinical manifestations

+

(?)c

Prostration

+++

+++

+++

+

Impaired consciousness

+++

++

+++

+++

Respiratory distress (acidotic breathing)

+++

+

+

++

Multiple convulsions

+++

+

+++

+++

Circulatory collapse

+

+

+++

+++

Pulmonary edema (radiological)

+/-

+

+++

++

Abnormal bleeding

+/-

+

++

+

Jaundice

+

+++

+

+

Hemoglobinuria

+/-

+

Laboratory findings

+

+

Severe anemia

+++

+

+++

+++

Hypoglycemia

+++

++

+++

+++

Acidosis

+++

++

+++

+++

Hyperlactatemia

+++

++

+/-

++

Hyperparasitemia

++

+

++

++

Renal impairment

+

+++

aSee the section on severe malaria in children.

bOn a scale from + to +++; +/- indicates infrequent occurrence.

cData not available.

SOURCE: World Health Organization. 2000. Severe falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene. 94 (suppl 1). Table 1, on p. S1/2 of this supplement, was incomplete. A corrected version was printed and inserted into the supplement.



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