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Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance (2004)
Board on Global Health (BGH)

Page
149
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The following HTML text is provided to enhance online readability. Many aspects of typography translate only awkwardly to HTML. Please use the page image as the authoritative form to ensure accuracy.


Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance

TABLE 6-2 Severe Manifestations of P. falciparum Malaria in Adults and Childrena

Prognostic Valueb

 

Frequencyb

Children

Adults

 

Children

Adults

Clinical manifestations

+

(?)c

Prostration

+++

+++

+++

+

Impaired consciousness

+++

++

+++

+++

Respiratory distress (acidotic breathing)

+++

+

+

++

Multiple convulsions

+++

+

+++

+++

Circulatory collapse

+

+

+++

+++

Pulmonary edema (radiological)

+/-

+

+++

++

Abnormal bleeding

+/-

+

++

+

Jaundice

+

+++

+

+

Hemoglobinuria

+/-

+

Laboratory findings

+

+

Severe anemia

+++

+

+++

+++

Hypoglycemia

+++

++

+++

+++

Acidosis

+++

++

+++

+++

Hyperlactatemia

+++

++

+/-

++

Hyperparasitemia

++

+

++

++

Renal impairment

+

+++

aSee the section on severe malaria in children.

bOn a scale from + to +++; +/- indicates infrequent occurrence.

cData not available.

SOURCE: World Health Organization. 2000. Severe falciparum malaria. Transactions of the Royal Society of Tropical Medicine and Hygiene. 94 (suppl 1). Table 1, on p. S1/2 of this supplement, was incomplete. A corrected version was printed and inserted into the supplement.

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149