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NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

This study was supported by Contract No. HRN-A-00-00-00012-00 between the National Academy of Sciences and the U.S. Agency for International Development (USAID) and the Bill and Melinda Gates Foundation. Any opinions, findings, conclusions, or recommendations expressed in this publication are those of the authors and do not necessarily reflect the views of the organizations or agencies that provided support for this project.

Library of Congress Cataloging-in-Publication Data

Saving lives, buying time : economics of malaria drugs in an age of resistance / Committee on the Economics of Antimalarial Drugs, Board on Global Health ; Kenneth J. Arrow, Claire Panosian, and Hellen Gelband, editors.

p. ; cm.

Includes bibliographical references and index.

ISBN 0-309-09218-3 (hardcover)

1. Antimalarials—Economic aspects. 2. Pharmaceutical policy. 3. Drug resistance in microorganisms.

[DNLM: 1. Malaria—drug therapy. 2. Antimalarials—economics. 3. Antimalarials—therapeutic use. 4. Drug Costs. 5. Drug Resistance. WC 770 S267 2004] I. Arrow, Kenneth Joseph, 1921- II. Panosian, Claire. III. Gelband, Hellen. IV. Institute of Medicine (U.S.) Committee on the Economics of Antimalarial Drugs.

RC159.A5S28 2004



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The serpent has been a symbol of long life, healing, and knowledge among almost all cultures and religions since the beginning of recorded history. The serpent adopted as a logotype by the Institute of Medicine is a relief carving from ancient Greece, now held by the Staatliche Museen in Berlin.

Cover photograph by Claire B. Panosian. Mkuranga, Tanzania, November 2002. Family and neighbors of Amina Selemani, including her daughter and newborn grandchild. Another grandchild, Zulfa Mshamu (not shown) received ACT treatment for malaria through a clinical research trial co-sponsored by the Ifakara Health Research and Development Centre and the U.S. Centers for Disease Control and Prevention.

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