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The Threat of Pandemic Influenza: Are We Ready? - Workshop Summary
Appendix A
Pandemic Influenza: Assessing Capabilities for Prevention and Response
June 16–June 17, 2004
The National Academies
Lecture Room
2101 Constitution Avenue, NW (C Street Entrance)
Washington, D.C.
AGENDA
Wednesday, June 16, 2004
8:00
Continental Breakfast
8:30
Welcome and Opening Remarks
Adel Mahmoud, MD, PhD
Chair, Forum on Microbial Threats
President, Merck Vaccines
8:35
Keynote Address: John M. Barry, Distinguished Visiting Scholar, The Center for Bioenvironmental Research at Tulane and Xavier Universities, and author of The Great Influenza: The Epic Story of the Deadliest Plague in History
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PLANNING AND PREPAREDNESS FOR PANDEMIC INFLUENZA
Session I: Global and National Preparedness Strategies
Moderator: Adel Mahmoud, MD, PhD, Chair, Forum on Microbial Threats/President, Merck Vaccines
9:05–9:35
WHO: Priority Public Health Interventions Before and During an Influenza Pandemic
Klaus Stöhr, DVM, Project Leader, Global Influenza Programme, Department of Communicable Disease Surveillance and Response, World Health Organization, Geneva
9:35–10:05
U.S. Government Pandemic Influenza Preparedness Plan Bruce Gellin, MD, Director, National Vaccine Program Office, U.S. Department of Health and Human Services
10:05
Q&A/Open Discussion
10:30
Break
Session II: Response and Discussion of Preparedness Planning
Moderator: Stanley Lemon, MD, Vice Chair, Forum on Microbial Threats and Dean of Medicine, The University of Texas Medical Branch at Galveston
10:45
Discussion Panel: David Fedson, MD, Sergy Haut, France
Nancy J. Cox, PhD, Chief, Influenza Branch, CDC and Director, WHO Collaborating Centre for Surveillance, Epidemiology and Control of Influenza
Dennis Perrotta, PhD, State Epidemiologist, Texas
Peter A. Shult, PhD, Director, Communicable Disease Division and Emergency Laboratory Response, Wisconsin State Laboratory of Hygiene
11:15
Open Discussion
12:00
Lunch
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The Threat of Pandemic Influenza: Are We Ready? - Workshop Summary
Session III: Obstacles and Opportunities for Optimal Preparedness
Moderator: Gary Roselle, MD, Program Director for Infectious Diseases, Department of Veterans Affairs Central Office
1:00–1:20
Partnering with the Private Medical System
Gordon Grundy, MD, Regional Medical Director, Aetna Inc.
1:20–1:35
Discussion
1:35–1:55
Vaccine Development and Production Issues
Philip Hosbach, Vice President of New Products and Immunization Policy, Aventis Pasteur SA
1:55–2:10
Discussion
2:10–2:30
Ensuring an Adequate Stockpile of Antivirals
Paul Brown, PhD, Global Task Force Leader for Tamiflu™ Pandemic Planning, F. Hoffmann La-Roche, Switzerland
2:30–2:45
Discussion
2:45–3:05
Chasing the Elusive Virus: Preparing for the Future by Examining the Past
Jeffery K. Taubenberger, MD, PhD, Chair, Department of Molecular Pathology, Armed Forces Institute of Pathology, U.S. Department of Defense
3:05–3:20
Discussion
3:20
Break
Session IV: Panel Discussion—Innovating Past Barriers
Moderator: Joshua Lederberg, PhD, Nobel Laureate, Sackler Foundation Scholar, Rockefeller University
3:30–3:45
Strategies for Control of Influenza by Targeting Broadly Conserved Viral Features
Suzanne Epstein, PhD, Center for Biologics Evaluation and Research, Food and Drug Administration
3:45–4:10
Mathematical Modeling: Containing Pandemic Influenza with Vaccines and Antivirals
Ira Longini, MD, Rollins School of Public Health, Emory University, Atlanta, GA
March Lipsitch, PhD, Harvard School of Public Health, Boston, MA
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4:10–4:25
“Insuring” for a Better Response
Martin Meltzer, PhD, National Center for Infectious Diseases, U.S. Centers for Disease Control and Prevention
4:25–4:40
Coordination Between the Public and Private Sectors
Jonathan B. Perlin, MD, PhD, MSHA, FACP, Acting Under Secretary for Health, Department of Veterans Affairs
4:40–5:30
Q&A/Open Discussion
5:30
Adjournment of the First Day
Thursday, June 17, 2004
BATTLING NATURE’S TERRORIST: SCIENTIFIC AND PUBLIC HEALTH TOOLS
8:00
Continental Breakfast
8:30
Opening Remarks/Summary of Day 1
Stanley Lemon, MD
Vice Chair, Forum on Emerging Infections
Session V: Methods for the Prevention and Containment of Pandemic Influenza
Moderator: Carole Heilman, PhD, Director, Division of Microbiology and Infectious Diseases, NIAID, NIH
8:45–9:15
A Report from the Field: The 2003–2004 H5N1 Outbreak
Robert Webster, PhD, Rose Marie Thomas Professor and Chair, Department of Infectious Diseases, St. Jude’s Children’s Research Hospital, Memphis, TN
9:15–10:15
Discussion Panel: Amin Soebandrio, MD, PhD, Assistant Deputy Minister for Research and Technology for Health and Medical Sciences, Indonesia
Nguyen Tien Dzung, DVM, PhD, Head of Virology, National Institute for Veterinary Research, Ministry of Agriculture and Rural Health Development, Vietnam
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Chantanee Buranathai, DVM, PhD, Chief, Emerging and Exotic Animal Disease Section, Division of Veterinary Epidemiology, Department of Livestock Development, Thailand
10:15–10:40
Strategies for Preventing and Controlling Avian Influenza and its Transmission within the Bird and Animal Population
Dewan Sibartie, DVM, PhD, Scientific and Technical Department, Office International des Épizooties (OIE)
10:40–11:45
Discussion Panel: Guus Koch, DVM, Central Institute for Animal Disease Control, Wageningen University and Research Centre, Lelystad, The Netherlands
David Swayne, DVM, PhD, Laboratory Director and Research Leader, Southeast Poultry Research Laboratory, U.S. Department of Agriculture
Carol Cardona, DVM, PhD, Poultry Extension Veterinarian and Assistant Professor, Veterinary Extension, University of California-Davis
Laurence S. Tiley, PhD, Lecturer in Molecular Virology, Centre for Veterinary Science, University of Cambridge, United Kingdom
11:45
Break
12:00–12:25
Enhancing Influenza Surveillance: From the Global to the Local Perspective
Nancy J. Cox, PhD, Chief, Influenza Branch, Centers for Disease Control and Prevention and Director, WHO Collaborating Centre for Surveillance, Epidemiology and Control of Influenza
12:25–1:00
Discussion
1:00
Lunch
Session VI: Panel Discussion—Priorities for Improving Preparedness
Moderator: Frederick Sparling, MD, Professor of Medicine, Microbiology, and Immunology, University of North Carolina
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2:00–2:20
Pandemic Influenza and Mortality: Past Evidence and Projections for the Future
Lone Simonsen, PhD, Office of Global Affairs, National Institute of Allergy and Infectious Diseases, National Institutes of Health
2:20–2:40
Increasing Awareness and Uptake of Influenza Immunization
Glen Nowak, PhD, Office of Health Communications, National Immunization Program, CDC
2:40–3:00
Public Communication Strategies to Remedy Panic in a Pandemic
Monica Schoch-Spana, PhD, Center for Biosecurity, University of Pittsburgh Medical Center
3:00–3:20
Preparing the Legal System for Pandemic Influenza
Larry Gostin, JD, Center on Law and the Public’s Health, Georgetown University
3:20
Open Discussion
5:00
Closing Remarks/Adjourn
DISCUSSANTS-AT-LARGE
David Bell, MD, Senior Medical Officer, Office of the Director, National Center for Infectious Diseases, Centers for Disease Control and Prevention
Timothy Booth, MD, Director, Viral Diseases Division, National Microbiology Laboratory, Health Canada, Canadian Science Centre for Human and Animal Health, Winnipeg, Ontario
Kathy Coelingh, PhD, Senior Director of Scientific and Regulatory Affairs, MedImmune Vaccines, Mountain View, CA
Jack Croddy, Senior Advisor, Office of Diplomacy, U.S. Department of State
William M. Egan, PhD, Acting Director, Office of Vaccines, Center for Biologics Evaluation and Research, U.S. Food and Drug Administration
Geoffrey Evans, MD, Medical Officer, Vaccine Injury Compensation Program, Health Resources and Services Administration, U.S. Department of Health and Human Services
Harold Foster, Deputy Director, Office of International Health Affairs, U.S. Department of State
Adolfo Garcia–Sastre, PhD, Associate Professor, Department of Microbiology, Mount Sinai School of Medicine, New York
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Kathleen F. Gensheimer, MD, MPH, State Epidemiologist and Director, Medical Epidemiology Section, Maine Bureau of Health, Department of Human Services
Robert A. Heckert, DVM, PhD, National Program Leader, Animal Health, Agricultural Research Service, U.S. Department of Agriculture
Charles Hoke, MD, Walter Reed Army Institute of Research, U.S. Army Medical Research and Materiel Command
Yanzhong Huang, PhD, Assistant Professor and Director, Center for Global Health Studies, John C. Whitehead School of Diplomacy and International Relations, Seton Hall University
Dominick Iacuzio, F. Hoffman La-Roche
George Kemble, PhD, Senior Director of Research, MedImmune Vaccines, Mountain View, CA
Richard F. Kingham, JD, Partner, Covington and Burling, Washington, DC, and London
David J. Lipman, MD, Director, National Center for Biotechnology Information, National Library of Medicine, National Institutes of Health
Nina Marano, DVM, MPH, Dipl. ACVPM, Associate Director for Veterinary Medicine and Public Health National Center for Infectious Diseases, Centers for Disease Control and Prevention
James T. Matthews, PhD, Director, External Research and Development, Aventis Pasteur Group, Swiftwater, PA
Michael McGuire, F. Hoffman La-Roche
Mark Miller, MD, Division of International Epidemiology and Population Studies, Fogarty International Center, National Institutes of Health
Arnold Monto, MD, Professor of Epidemiology, Director of the University of Michigan Bioterrorism Preparedness Initiative, School of Public Health, University of Michigan, Ann Arbor
Stuart Nightingale, MD, Senior Advisor, Office of the Assistant Secretary for Public Health Emergency Preparedness, U.S. Department of Health and Human Services
Tara O’Toole, MD, MPH, Center for Biosecurity, University of Pittsburgh Medical Center
Michael Perdue, PhD, Research Leader, Environmental Microbial Safety Laboratory, Animal & Natural Resources Institute, Agricultural Research Service, U.S. Department of Agriculture
Sara Radcliffe, MPH, Director, Science Policy and Bioethics, Biotechnology Industry Organization
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Stewart Simonson, Assistant Secretary for Public Health Emergency Preparedness, Office of Public Health Emergency Preparedness, U.S. Department of Health and Human Services
Eve Slater, MD, former Assistant Secretary for Health, U.S. Department of Health and Human Services
Rick Smith, MD, Office of Special Programs, Healthcare Emergency Preparedness, Health Resources and Services Administration, U.S. Department of Health and Human Services
Kanta Subbarao, MD, Senior Investigator, Respiratory Viruses Section, National Institute for Allergy and Infectious Diseases, National Institutes of Health
Susan C. Trock, DVM, MPH, DACVPM (Epi), New York State Department of Agriculture and Markets
Clara Witt, VMD, MPH, Global Emerging Infections Surveillance System, U.S. Department of Defense
Representative terms from entire chapter:
infectious diseases