ous Exposure Guidance Levels for Selected Submarine Contaminants in 2002.
Members of the COT subcommittee were selected for their expertise in inhalation toxicology, neurotoxicology, immunotoxicology, reproductive and developmental toxicology, veterinary pathology, pharmacokinetics, epidemiology, and human-health risk assessment. The subcommittee was specifically asked to accomplish the following tasks:
Evaluate the Navy’s current and proposed 1-h and 24-h EEGLs and 90-day CEGLs for the following substances: 2190 oil mist, formaldehyde, acrolein, ozone, monoethanolamine, nitric oxide, nitrogen dioxide, oxygen, carbon dioxide, carbon monoxide, methanol, ammonia, benzene, hydrazine, Freon 12, Freon 114, hydrogen, toluene, and xylene.
Determine whether the current or proposed guidance levels are consistent with the scientific data and whether any changes to the Navy’s exposure levels should be made on the basis of the subcommittee’s evaluation.
For two submarine contaminants for which no guidance levels exist—surface lead and 2,6-di-t-butyl-4-nitrophenol—determine whether sufficient data are available to develop EEGLs and CEGLs, and if sufficient data are available, provide recommendations for guidance levels consistent with the data.
Identify deficiencies in the database relevant to EEGL and CEGL development for the selected chemical substances, and make recommendations for future research, when appropriate.
To accomplish its review, the subcommittee was asked to use the Navy’s supporting documentation and other relevant toxicologic and epidemiologic data and publish the results of its evaluations in two separate reports. This is the subcommittee’s first report. It contains the EEGL and CEGL recommendations for the following chemicals of concern to the Navy: acrolein, carbon dioxide, carbon monoxide, formaldehyde, hydrazine, methanol, monoethanolamine, nitric oxide, nitrogen dioxide, and oxygen. The remaining chemicals will be addressed in the second report.