TABLE D.1 Description of Cohort Studies Related to Exposure to Fuels and Combustion Products

Reference

Population

Study Group

Health-Outcome Assessment

Exposure Assessment

Analysis, Adjustment for Potential Confounders

Imperial Oil Cohort

Hanis et al. 1979

Mortality experience (1964–1973) of male Imperial Oil workers (at least 1 yr for active workers; at least 5 yrs for inactive workers) in Canada; internal comparison of refinery and non-refinery workers

15,032; 5,731 refinery, 9,301 non-refinery

Vital status followed through provincial registrars, Statistics Canada

Job titles classified as in or outside refinery work

RR; age

Schnatter et al. 1992

Mortality experience (1964–1983) of Imperial Oil workers (at least 1 yr) in Canada; external comparison with Canadian general population

34,597

Vital status followed through Statistics Canada, internal data sources, NDI

Company employment in 11 operating segments and HC exposure assigned by industrial hygienists on basis of detailed work histories

SMR; sex, age, calendar period

Schnatter et al. 1993

Mortality experience (1964–1983) of male Imperial Oil petroleum-marketing and distribution workers (at least 1 yr) in Canada; external comparison with Canadian general population

6,672

Vital status followed through Statistics Canada, internal data sources, NDI

HC exposure frequency assigned by industrial hygienists based on basis of detailed work histories

SMR; sex, age, calendar period

Schnatter et al. 1996

Nested cases of lymphohematopoietic malignancies among Imperial Oil workers (at least 1 yr) in Canada; internal controls selected from males in cohort, matched 4:1 on age and were alive at case date of death

14 leukemia

7 MM

8 NHL

Cause of death on death certificates coded by Statistics Canada

Company employment in 11 operating segments and HC exposure assigned by industrial hygienists on basis of detailed work histories

Mantel-Haenszel OR; age, smoking, family cancer history, frequency of chest x rays

Lewis et al. 2000

Mortality experience (1964–1994) of Imperial Oil workers (at least 1 yr in 1964–1983) in Canada; external comparison with Canadian general population

34,560

Vital status followed through Statistics Canada, internal data sources, NDI

Company employment in 11 operating segments and presumed HC exposure derived from job titles

SMR; sex, age, calendar period



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