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Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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PRELIMINARY CONSIDERATIONS REGARDING NASA’S BIOASTRONAUTICS CRITICAL PATH ROADMAP

Interim Report

Committee on Review of NASA’s Bioastronautics Critical Path Roadmap

Board on Health Sciences Policy

INSTITUTE OF MEDICINE OF THE NATIONAL ACADEMIES

THE NATIONAL ACADEMIES PRESS
Washington D.C.
www.nap.edu

Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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THE NATIONAL ACADEMIES PRESS
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NOTICE: The project that is the subject of this report was approved by the Governing Board of the National Research Council, whose members are drawn from the councils of the National Academy of Sciences, the National Academy of Engineering, and the Institute of Medicine. The members of the committee responsible for the report were chosen for their special competences and with regard for appropriate balance.

This study was supported by Contract No. NASW-02031 #103 between the National Academy of Sciences and the National Aeronautics and Space Administration. Any opinions, findings, or conclusions expressed in this publication are those of the author(s) and do not necessarily reflect the view of the organizations or agencies that provided support for this project.

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Copyright 2005 by the National Academy of Sciences. All rights reserved.

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Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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“Knowing is not enough; we must apply.

Willing is not enough; we must do.”

—Goethe

INSTITUTE OF MEDICINE OF THE NATIONAL ACADEMIES

Adviser to the Nation to Improve Health

Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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THE NATIONAL ACADEMIES

Advisers to the Nation on Science, Engineering, and Medicine

The National Academy of Sciences is a private, nonprofit, self-perpetuating society of distinguished scholars engaged in scientific and engineering research, dedicated to the furtherance of science and technology and to their use for the general welfare. Upon the authority of the charter granted to it by the Congress in 1863, the Academy has a mandate that requires it to advise the federal government on scientific and technical matters. Dr. Bruce M. Alberts is president of the National Academy of Sciences.

The National Academy of Engineering was established in 1964, under the charter of the National Academy of Sciences, as a parallel organization of outstanding engineers. It is autonomous in its administration and in the selection of its members, sharing with the National Academy of Sciences the responsibility for advising the federal government. The National Academy of Engineering also sponsors engineering programs aimed at meeting national needs, encourages education and research, and recognizes the superior achievements of engineers. Dr. Wm. A. Wulf is president of the National Academy of Engineering.

The Institute of Medicine was established in 1970 by the National Academy of Sciences to secure the services of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public. The Institute acts under the responsibility given to the National Academy of Sciences by its congressional charter to be an adviser to the federal government and, upon its own initiative, to identify issues of medical care, research, and education. Dr. Harvey V. Fineberg is president of the Institute of Medicine.

The National Research Council was organized by the National Academy of Sciences in 1916 to associate the broad community of science and technology with the Academy’s purposes of furthering knowledge and advising the federal government. Functioning in accordance with general policies determined by the Academy, the Council has become the principal operating agency of both the National Academy of Sciences and the National Academy of Engineering in providing services to the government, the public, and the scientific and engineering communities. The Council is administered jointly by both Academies and the Institute of Medicine. Dr. Bruce M. Alberts and Dr. Wm. A. Wulf are chair and vice chair, respectively, of the National Research Council.

www.national-academies.org

Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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COMMITTEE ON REVIEW OF NASA’S BIOASTRONAUTICS CRITICAL PATH ROADMAP

DAVID E. LONGNECKER (Chair), Professor of Anesthesia,

University of Pennsylvania

JAMES P. BAGIAN, Director,

National Center for Patient Safety, Department of Veterans Affairs, Veterans Health Administration

ELIZABETH CANTWELL, Director,

External Relations, Homeland Security Organization, and Micro and Nano Technology Section Leader, Lawrence Livermore National Laboratory

VALERIE GAWRON, Fellow,

General Dynamics

CHRISTOPHER HART, Assistant Administrator for System Safety,

Federal Aviation Administration

THOMAS TEN HAVE, Professor of Biostatistics,

Center for Clinical Epidemiology and Biostatistics, University of Pennsylvania School of Medicine

CHARLES LAND, Senior Investigator,

Division of Cancer Epidemiology and Genetics, National Cancer Institute

DANIEL R. MASYS, Director of Biomedical Informatics and Professor of Medicine,

University of California, San Diego

BRUCE MCCANDLESS II, Research Scientist,

Advanced Space Transportation Systems, Lockheed Martin Space Systems Company

TOM S. NEUMAN, Professor of Medicine and Surgery,

University of California, San Diego, San Diego Medical Center

THOMAS F. OLTMANNS, E. J. Swift Professor of Arts and Sciences,

Department of Psychology, Washington University

LAWRENCE A. PALINKAS, Professor,

Department of Family and Preventive Medicine, University of California, San Diego

JAMES PAWELCZYK, Associate Professor of Applied Physiology and Kinesiology,

Pennsylvania State University

BRUCE S. RABIN, Professor of Pathology and Psychiatry, Medical Director,

University of Pittsburgh Medical Center Healthy Lifestyle Program

KARLENE ROBERTS, Professor of Business Administration,

Haas School of Business, University of California, Berkeley

CAROL SCOTT-CONNER, Professor of Surgery,

University of Iowa Hospitals & Clinics

Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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MARGARET RHEA SEDDON, Assistant Chief Medical Officer,

Vanderbilt Medical Group

JAY R. SHAPIRO, Professor of Medicine,

Department of Medicine, Uniformed Services University and

Director,

Osteogenesis Imperfecta Program, Kennedy-Krieger Institute

IOM STAFF

LISA M. VANDEMARK, Study Director

ANDREW M. POPE, Director,

Board on Health Sciences Policy

MELVIN H. WORTH, JR., Scholar-in-Residence

BENJAMIN N. HAMLIN, Research Associate

ERIN MCCARVILLE, Senior Project Assistant

DIVISION ON ENGINEERING AND PHYSICAL SCENCES STAFF

SANDRA GRAHAM, Senior Program Officer

MAUREEN MELLODY, Program Officer

Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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Reviewers

This report has been reviewed in draft form by individuals chosen for their diverse perspectives and technical expertise, in accordance with procedures approved by the NRC’s Report Review Committee. The purpose of this independent review is to provide candid and critical comments that will assist the institution in making its published report as sound as possible and to ensure that the report meets institutional standards for objectivity, evidence, and responsiveness to the study charge. The review comments and draft manuscript remain confidential to protect the integrity of the deliberative process. We wish to thank the following individuals for their review of this report:


JOHN R. BALL, American Society for Clinical Pathology

DAVID W. GAYLOR, Gaylor & Associates

AL HARRISON, Department of Psychology,University of California, Davis

JOHN KINDINGER, Los Alamos National Laboratory

DAVID M. KLAUS, BioServe Space Technologies, University of Colorado

LAWRENCE G. RAISZ, University of Connecticut Health Center

COURTNEY STADD, Capitol Solutions

Page viii Cite
Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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Although the reviewers listed above have provided many constructive comments and suggestions, they were not asked to endorse the conclusions nor did they see the final draft of the report before its release. The review of this report was overseen by Mary Jane Osborn, University of Connecticut Health Center. Appointed by the National Research Council and the Institute of Medicine, she was responsible for making certain that an independent examination of this report was carried out in accordance with institutional procedures and that all review comments were carefully considered. Responsibility for the final content of this report rests entirely with the authoring committee and the institution.

Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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Suggested Citation:"Front Matter." Institute of Medicine. 2005. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap: Interim Report. Washington, DC: The National Academies Press. doi: 10.17226/11191.
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Extending the spatial and temporal boundaries of human space flight are important goals for the National Aeronautics and Space Administration (NASA), yet human space flight remains an endeavor with substantial risks. Potential hazards include exposure of the crew to space radiation, degraded crew performance related to human behavioral and other health changes, failure of life support systems, and the adverse effects of space flight on human biological systems. The Bioastronautics Critical Path Roadmap (BCPR) is designed to provide summary assessments of the importance of each risk, and the current state of science and technology with respect to minimizing them. Preliminary Considerations Regarding NASA's Bioastronautics Critical Path Roadmap assesses the strengths and weaknesses of the content and processes of the BCPR as applied to the missions described in the President's exploration initiative and identifies the unique challenges for accomplishing its goals and objectives.

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