TABLE A-1 Epidemiologic Studies—Occupational Exposure

Reference

Study Design

Description

Study Group (N)

Comparison Group (N)a

PRODUCTION WORKERS

NIOSH Studies Reviewed in Update 2002

Steenland et al., 2001

Cohort

A study to reexamine and compare diabetes data from the NIOSH cohort and the United States Air Force Ranch Hands in order to reconcile differences between the two study methods and protocols

267 NIOSH workers 990 Ranch Hand subjects

227 NIOSH comparisons 1,275 Ranch Hand comparisons

NIOSH Studies Reviewed in Update 2000

Calvert et al., 1999

Cohort

Continuing follow-up of workers employed more than 15 years ago at two plants that manufactured substances contaminated with TCDD to evaluate associations between serum TCDD and serum glucose (diabetes), TSH, total T4, and T3

281

260

Steenland et al., 1999

Cohort

Mortality study of workers at 12 industrial plants that produced chemicals contaminated with TCDD, using a job-exposure matrix to estimate TCDD exposure categories. Endpoints reported are all cancers, ischemic heart disease, and diabetes

5,132 (3,538 with exposure data divided into septiles of cumulative exposure; 608 with chloracne)



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