TABLE A-3 Epidemiologic Studies—Veterans’ Exposure

Reference

Study Design

Description

Study Group (N)

Comparison Group (N)a

UNITED STATES STUDIES

New Ranch Hand Studies

Akhtar et al., 2004

Cohort

Follow-up to Ketchum et al. (1999), comparing cancer incidence among Ranch Hands with Vietnam veterans who served in Southeast Asia but did not spray herbicides and with US national cancer rates

1,189 Ranch Hands for external analysis; 1,009 Ranch Hands for internal analysis

1,776 Comparison subjects for external analysis; 1,429 comparison subjects for internal analysis

Barrett et al., 2003

Cohort

Serum TCDD measurement and psychological functioning among Ranch Hand veterans

1,109

1,493

Michalek et al., 2003

Cohort

Correlation for TCDD elimination and Ranch Hands with diabetes

343

No comparison group

Pavuk et al., 2003

Cohort

Study to examine the relationship between serum TCDD and thyroid function in Ranch Hand veterans

1,009

1,429

Ranch Hand Studies Reviewed in Update 2002

Barrett et al., 2001

Cohort

Based on tests of cognitive function in 1982, and dioxin levels measured in 1987 and 1992; analyzed association between serum dioxin levels and cognitive function among Ranch Hand veterans

937

1,052

Michalek et al., 2001a

Cohort

Based on physical examination through 1992 and medical records reviewed through March of 1993; analyzed association between serum dioxin levels and hepatic abnormalities among Ranch Hand veterans

1,109

1,493



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