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Spinal Cord Injury: Progress, Promise, and Priorities (2005)
Board on Neuroscience and Behavioral Health (NBH)

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. "6 Developing New Therapeutic Interventions: From the Laboratory to the Clinic." Spinal Cord Injury: Progress, Promise, and Priorities. Washington, DC: The National Academies Press, 2005.

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Spinal Cord Injury: Progress, Promise, and Priorities

Quality of life

 

Activities of Daily Living (ADL)

 

Measures basic tasks of everyday living

 

Is used as a predictor of admission to nursing homes and hospitals

 

Lots of variation, depending on which items are measured and how a disabling condition is classified

 

SF-12, SF-36, and SF-54

 

Measure changes in quality of life, mental health, pain, and social function

 

Reflect the individual’s perceptions and preferences about physical, emotional, and social well-being

 

Hard to detect changes in quality of life over time

 

Questions about walking can be construed as offensive to individuals with spinal cord injuries

 

International Classification of Impairment, Disabilities, and Handicaps (ICIDH)

 

Was designed by the World Health Organization to classify the consequences of disease and their implications on the patient’s life

 

Defines impairment, disabilities, and handicaps

 

ICIDH-2 incorporates disability as a dynamic process and holds that environmental factors can influence the impairment

 

Needs Assessment Checklist (NAC)

 

Is used as a rehabilitation outcome measure designed specifically for spinal cord injury population

 

Uses a 4-point scale

 

Consists of 199 behavioral indicators that assess patient achievement in nine categories required for maintenance of health and quality of living

 

Is not subject to floor or ceiling effects

NOTE: MEPs = motor evoked potential; SSEP = somatosensory evoked potential.

assessment (Curt et al., 2004). In addition, the International Collaboration on Repair Discoveries (ICORD) has recently published a set of guidelines for clinical trials (ICORD, 2004) and is in the process of developing clinical outcome measures for each type of intervention.

Given the heterogeneity between individuals in terms of the types and severities of their spinal cord injuries (see Table 1-2 and Chapter 2), not only is a common set of outcome measures required, but an integrated rating scale for the assigned set of outcome measures should also be designed. This will improve efforts to define clinical trial end points, monitor the progression of an individual’s treatment, and examine the effects of the treatment intervention on the multiple complications associated with a spinal cord injury.

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