The principles articulated in this report should be used to determine the optimal inventory size; current evidence suggests that additional units would generate health benefits at an acceptable cost.
Increases in the size of the national cord blood unit inventory would result in increased access to units appropriate for clinical use, which is associated with improved patient outcomes. The characteristics of what constitutes an acceptable unit for transplantation should be reevaluated by simultaneously considering both cell dose and HLA match.
Howard DH, Maiers M, Kollman C, Logan B, Gragert L, Setterholm M. 2005. A cost-benefit analysis of increasing cord blood inventory levels: An analysis prepared for the Committee on Establishing a National Cord Blood Stem Cell Bank, Institute of Medicine, Washington, DC.
Vigdor ER. 2003. Coverage does matter: The value of health forgone by the uninsured. Hidden Costs, Value Lost: Uninsurance in America. Washington, DC: The National Academies Press.