cell dose are confounded in that only young children are capable of receiving high cell doses. For example, Table G-4 reveals that only 2 percent of the high cell doses were transplanted into patients over 16 years of age. Since cell dose is expressed as TNC/kg, presumably there are few units that have sufficient numbers of cells to yield ratios above 5 × 107 TNC/kg for adults. Research into the viability of combining multiple units for a single transplant should be investigated. Finally, analysis of larger datasets with larger cell volumes and greater numbers of perfectly matched recipients is needed to confirm these preliminary results.


Gibbons RD, Duan N, Meltzer D, Pope A, Pehoet ED, Dubler NN, Francis CK, Gill B, Guinan E, Henderson M, Ildstad ST, King PA, Martinez-Maldonado M, Mclain GW, Murray JE, Nelkin D, Spellman MW, and Pitluck S. 2003. Waiting for organ transplantation: Results of an analysis of an Institute of Medicine committee. Biostatistics 42:207–222.

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