but rather to start with the presumption that the work is important for human welfare, that it will be done, and that it should be conducted in a framework that addresses scientific, ethical, medical, and social concerns. The public increasingly supports this area of research and its potential to advance human health.
The next chapter describes the current status of research involving hES cells. It also addresses possible novel sources of hES cell lines not yet developed and the use of human/nonhuman chimeras in research.
Chapter 3 focuses on ethical and policy issues and how existing and proposed guidelines address them. In Chapter 3, the committee proposes a local review mechanism to oversee research involving hES cells. It also recommends establishing a national body to periodically update the guidelines recommended in this report and assess the status of the field. Chapter 4 describes the current legal and regulatory environment of hES cell research in the United States and around the world. Chapter 5 addresses recruitment of donors and the informed consent process and makes recommendations about review of the processes by which donated materials are obtained. Chapter 5 also discusses the need for some standards in the banking and maintenance of hES cell lines. The final chapter consolidates the recommendations made in previous chapters as formal guidelines.