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110 - Manual sobre Cuidados e Usos de Animals de Laborar6rlo APENDICE A Bibliografia Selecionada Adminlsrracao e Manejo, 111 Alternatlvas, 111 Anestesla, Dor e Clrurgla, 112 Anfiblos, Reptels e Pelxes, 114 Anlmals de Fazenda, 115 Animais Ex6tlcos, Sllvestres e de Zool6glcos, 116 Aves, 117 Bem-Estar, 117 Contamlnantes Amblentals, 117 Culdados com Animals de Laborat6rlo, 118 Enrlqueclmento, 119 Enslno Tecnlco e Profisslonal, 120 Etl ca, 1 21 Eutanas la, 121 Farmacologla e Terapeutlca, 122 Gatos e Caes, 122 Genetlca e Nomenclatura, 122 Lels, Regulamentos e Politlcas, 123 Modelos e Recursos Animals, 123 Nutrlsao, 124 Outros Anlmals, 126 Parasltologla, 127 Patologla e Patologla Chnlca, 127 Perlddlcos, 128 Planejamento e Construcao de Blotcrlos, 130 Prlmatas Nao-Humanos, 131 Referenclas Gerals, 132 Rlscos Blol6glcos em Pesqulsa Animal, 133 Roedores e Coelhos, 134 Tamanho da Amostra e Desenho Experimenral, 137

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Apendice A - Bibliografia Selecionada - 111 ADMINISTRA(;AO E MANEJO Animal Care and Use Committees Bibliography T Allen and K. Clingerman. 1992. Beltsville, Md.: U.S. Department of Agriculture, National Agricultural Library (Publication ~SRB92-16). 38 pp. Animal Care and Use: Policy Issues in the 1990=s. National Instirures of Health/ Of fice for the Protecr on from Research Risks (NIH/O P RR). I 989. Proceedings of ~ NIH/OPRR Conference, Bethesda, Md. hi Cost An alys is and Rate Setring Manual for An i m al Resource Faci ines. Animal Resources Program (ARP), Division of Research Resources (DRR), National Institutes of .; Health (NIH). 1979 revised. NIH Pub. Into. 80 ~006. Washington, D.C.: U.S. Department of Health, Education and Welfare. 115 pp. (Available from ARP, DRR, NIH, Building 31, Room SB59, Bethesda, MD 20205). Effective Animal Care and Use Committees. F. B. Orlans, R. C. Simmonds, and W. J. _ Dodds, eds. 1987. In Laboratory Animal Science, Special Issue, January 1987. ~ Published in collaboration with the Scientists Center for Animal Welfare. - ~ Essentials So r Animal Research: A Primer for Research Personnel. B. T Bennett, M. J. Brown, and ). C. Schofield. 1994. Beltsville, Md.: National Agricultural Library 126 pp. Guide to the Care and Use of Experimental Animals, Volume I, 2 rid ed. E. D. Olfert, B. M. Cross, and A. A McWilliam, Ed. 1993. Ontario, Canada: Canadian Council on Animal Care. 211 pp. Institutional Animal Care and Use Committee Guidebook. INIH :0 PRR 1992. 1\ i H. Pub. 92-3415. (IACIUC duties, special considerations, federal regulations, references and resources.) Laboratory Animal Medical Subject Headings, A Report. NRC (National Research Council).1972. A report of the ILAR (Institute of Laboratory Animal Resources) Cc mm itree on Laboratory Animal Literature. Washington , D . C. : N a tional Academy of S ciences. 212 pp. Reference Materials for Members of Animal Care and Use Committees. D. J. Berry 1991. Beltsville, Md.: U.S. Department ofAgricultute, National Agricultural Library(AWICseries#10).42pp. ALTERNATIVAS Alternative Methods for Toxicity Testing: Regulatory Policy Issues. EPA-230/ 12-85-029. NTIS PB8-6- 113404/AS. Of fice of Policy, Planning and Evaluation, U.S. Environmental Protection Agency. Washington, DC 20460.

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112 - Manual sobre Culdados e Usos de Animals de Laborarbrlo Alternatives to Animal Use in Research, Testing, and Education. Of lice of Tech n Slug; Assessment (OTA-BA-273). U.S. Gov Printing Office. Washington, DC 20402. Alternatives to Current Uses of Animals in Research, Saferf Testing, and Education. M. L. Stephens.1986. Washington, D. C.: Humane Socier7 of the United States. 86 pp. Alternatives to Pain in Experiments on Animals. D. Pratt.1980. Argus Archives. 283 PP Animals and Alternatives in Testing: History Science, and Ethics. J. Zurlo, D. Rudacile, and A. M. G ale berg. l 994. New York: Mary Ann Liebert Publishers. 86 pp. The Principles of Humane Experimental Techniques. W. M. S. Russell and R. L. Burch. 1959. London: Methuen fix Co. 238 pp. (Reprinted as a Special Edition in 1992 by the Universities Federation for Animal Welfare.) ANESTESIA, DOR E CIRURGIA Anesthesiology: SelectedTopics in LaboratoryAnimalMedicine.Vol.5. S. H. Cramler and E. F. Jones. 1976. Brooks Air Force Base, Tex.: U.S Air Force School of Aerospace Medicine. 110 pp. (Available as Accession No. ADA 031463 from NationalTechnical information Service, U.S. Deparmment of Commerce, Springfield, VA 22161). Animal Pain. Perception and Alleviation. R. L. Kitchell, H. H. Erickson, E. Carsrens, and L. E. Davis. 1983. Bethesda, Md.: American Physiological Societv. 231 pp. Animal Pain Scales and Public Policy E B. Orlans. 1990.ATLA. 18:41-50. Animal PhysiologicSurgery2nded. C. M. Lang, ed. 1982. New York: Springer-Verlag. 180pp. Basic Surgical Exercises Using Swine. M. M. Swindle.1983. New York: Praeger. 254 Canine Surgery: AText and ReferenceWork 2nd ed. J. Archibald, ed. 1974. Wheaton, 111.: American Veterinary Publicarions. 1172 pp. (Publisher is now located in Santa Barbara, Calif ). Categories of Invasiveness in An imal Experiments. Canadian Council on Animal Care. 1993. Guide ro the Care and Use of Experimental Animals. Vol I (2nd ed.). Appcudix SV-B, pp. 201-202. Comparative Anesthesia in LaboratoryAnimals. E. V Miller, M. Ben, and J. S. Cass, eds. 1969. Fed. Proc. 28:1369-1586 and index. Experimental Surgery in Farm Animals. R. W. Dougherty.1981. Ames: lowa State UniversityPress.146pp. Experimenral Surgery: including Surgica Physiolog7. Srh ed J. Markowitz, J. Archiba d and H. G. Downie.19G4. Balrimore: Williams andWilkins. G59 pp. Experimen tal and Surgical Technique in the Rat. H. B. Waynforth and P. A. Flecknell. 1992. New York: Academic Press. 400 pp.

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Aptndice A - BibliograSa Selecionada 113 Fundamental Techniques in Veterinary Surger - 3rd ed. C. B. Knocked, A. R. Allen, D. J. Williams, and J. H. Johnson.1987. Philadelphia: W. B. Sawlders.3G8 pp. Guidelines on the recognition of pain, distress and discomfort in experimental animals and an hypothesis forassessment. D. B. Morton and P. H. M. Griffidhs.1985.Vet. Rec. IIG:431-43G. Laboratory Animal A l! esthesia: An I n trod UCt. OCR for page 110
114 Manual sobre Cuidados r Usos de Animals de l~borarcino Textbook of Veterinary Anesthesia. L. R. Soma, ed. 1971. Bal timore: Williams and Wilkins. 621 pp. Veterinary Anesthesia. 2nd ed. W. V Lumb and E. W. Jones. 1984. Philadelphia: Lea and Febiger. 693 pp. ANF[B105, REPTEIS E PEIXES Artificial Seawaters: Formulas and Methods. J. P. Bidwell and S. Spotte.1985. Boston: Jones and Bartlett. The Care and Use of Amphibians, Reptiles, and Fish in Research. D. O Schaeffer, K. M. K einow, and L. Krulisch, eds. l 992. Proceedings from a S CAW/LSU-SVM- sponsoredconference,April8-9,1991, New Orleans, La. Greenbelt Md.: Scientists Center for Animal Welfare. Disease Diagnosis and Control in North American Marine Aquaculture. 2nd rev ed. C. J. S inderrna art and D. V. Lichtner.1988. New York: Elsevier 426 pp. Diseases of Fishes, Book 2A, Bacterial Diseases of Fishes. G. L. Bullock, D. A. Conroy, and S. F. Snieszko.1971. Neptune, N.J.: T F H. Publications. 151 pp. Diseases of Fishes, Book 2B, Identification of Fish Pathogenic Bacteria. G. L. Bullock, 1971. Neptune,N.J.:T F. H. Publicarions.41 pp. Diseases of Fishes. Book 4, Fish immunology. D. P. Anderson. 1974. Neptune, 1\ .J.: T. F. H. Publications 239 pp. Diseases of Fishes, Book 5, Environmental Stress and Fish Diseases. G. A. Wederneyer, F. P. Meyer, and L. Smith. 1976. Neptune, N !. T. F. H. Publications. 192 pp. Fish Pathology, 2nd ed. R. J. Roberts, ed. 1989. London: Saunders. 448 pp. GuidelinesfortheUseofFishesin Field Research. C. H ebbs, J G. Nickum, and J. R. Hunter. 1987. Joint publication of the American Society of ichthyologists and Herpetologists, the American Fisheries Sociery, and the American institute of Fisheries Research Blologl,ts. 12 pp. Guidelines for the Use of Live Amphibians and Reptiles in Field Research. V H. Hutchinson, ed. ] 987. Joint publication of the American Society of ichthyologists and Herpetologists, The Herpetologists= League, and the Society for the Study of Amphibians and Reptiles. 14 pp. Information Resources for Reptiles, Amphibians, Fish, and Cephalopods Used in Biomedica Research. D. J. Berry, M. D. Kreger, J. L. Lyons-Carrer 1992. Beltsville, of d. : USDA l\iauollal Library Animal Welfare I n formation Center 87 pp. Laboratory Anatomy of the Turtle. L. M. Ashley 1955. Dubuque, Iowa: Wm. C. Brown. 48 pp. Parasites of Freshwater Fishes: A Review of Their Treatment and Control. G. L. Hoffman and F. P. Meyer.1974. Neptune, N.J.: T. F. H. Publications. 224 pp. The Pa bolog; of Fishes. W E. Ribelm and G. Migaki, eds. 1975. Madison: University nfWiccnnsin.1004 or.

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Apdodice A - Bibliograf a Selecionada 1 i 5 ANIMAIS DE FAZENDA Behavior of Domestic Animals. B. L. H art. i 98 5. New York: W. H. Freeman 390 pp. The Biology of the Pig. W. G. Pond and K. A. Houpt.1978. Ithaca, N.Y: Comsrock Publishing. 371 pp. The Calf ManagementandFeeding.5thed.J. H. B. Roy 1990. Boston: Buttetworths. Clinical Biochemistry of Domestic Anitnals. 4th cd. J. J. Kaneko, cd. l 989. New York: Academic Press. 93Z pp. Current Veterinary Therapy Food Animal Practice. J. L. Howard, cd. 1981. Philadelphia: W. B. Saunders.1233 pp. Current Veterinary Therapy: Food Animal Practice Two. J. L. Howard, ed. 1986. Philadelphia: W. B. Saunders.1008 pp. Current Veterinary Therapy. Food Animal Practice Three. J. L. H oward, cd. 1992. Philadelphia: W. B. Saunders.1002 pp.Diseases of Poultry 9th cd. B. W. Calnek et al., eds.1991.Ames: Iowa State Unit ersiry Press. 9ii pp. Diseases of Sheep. R. Jensen.1974. Philadelphia Lea and Febiger 389 pp. Diseases of Swine.7rh cd. A. D. Lemon et al., eds. l 992. A nes: Iowa State University Press.1038 pp. Domesticated Farm Animals in Medical Resealch. R. E. Doyle, S. Garb, L. E. Davis, D. K. Meyer, and F. W. Clayron.1968. Ann. N.Y Acad. Sci. t 47: 129-204. Dukes= Physiology of Domestic Animals. 11 th rev cd. M. J. Swenson and W. O. Reece, eds. 1993. Ithaca, N.Y: Cmtlstock Publisll,llg. 928 pp. Essentials of Pig Anatomy W. O. Sack.1982. Ithaca, N.Y: VeterinatyTe rtbooks. 192 pp. Farm Anima Housing and Welfare. D. H. Baxter, M. R. Ba tter, J. A. C. MacCormack, et al., eds. l 983. Boston: Nijhoff 343 pp. Farm Animal Welfare, January 1979-April 1989. C. N. Bebee and J. Swanson, eds. 1989. Beltsville, Md.: U.S. Department of Agriculture, National Agricultural Library 301 pp. Farm Animals and the Environment. C. Phillips and D. Piggins, cc 5. 1')9'. Wallingford, state: CAB Internauonal. 430 pp. Indicators Relevant to Farm Animal Welfare. D. Smidr, cd. l 983. Boston iNijhoft 251 pp. Livestock behavior and the design of livestock handling facilities. T Grandin.1991. Pp. 96-125 in Handbook of Facilities Planning. Volume 2: Labortory Animal Facilities, T Ruys, cd. New York: Van Nostrand.422 pp. Management and Welfare of Farm Animals 3rd cd. UFAW (Universities Federation forAnimalWelfare).1988. London: BailliemTilldall. 260 pp. Nematode Parasites of DomesucAnimals and of Man. N. D Levine.1968. Minneapolis, Minn.: Burgess Publishing.600 pp. Pathology of DomesticAnimals. 4th ed. K. V Jubb etal., eds. l992. Vol. l, 780 pp.; Vol.2,653 pp. New York: Academic Press.

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I 16 - Manual sobre Cuidados e Usos de An n ais de Labora or 0 The Pig as a Laboratory Animal. L. E. Mount and D. L. lngram.1971. New York: Academic Press. 175 pp. The Protection of Farm Animals, 1979-April 1989: Citations From AGRICOLA Concerning Diseases and Other Environmental Considerations. C. N. Bebee, cd. 1989. Beltsville, Md.: U.S. Department of Agriculture, National Agricultural Library 456 pp. Reproduction in Farm Animals. E. S. E. Hafez.1993. Philadelphia: Lea and Febiger 500 pp. Restraint of Domestic Animals. T. F. Sonsthagen. 1991. American Veterinary Publications. Ruminants: Cattle, Sheep, and Goats. Guidelines for the Breeding, Care and Managemen r o f Laboratory Animals. NRC (National Research Council).1974. A report of the ILAR (Institute of Laboratory Animal Resources) Commirree on Standards, Subcommittee on Standards for Large (Domestic) Laboratory Animals. Washington, D. C.: National Academy of S cie n ces. 72 pp. The Sheep as an ExperimentalAnimal.J. F Heck et 1983. NewYork: Academic Press. 216 pp. Swine as Models in Biomedical Research. M. M. Swindle.1992. Ames: Iowa State University Press. Swine in Cardiovascular Research. Vol. l and 2. H. C. Stanton and H. J. Mersmann. 1986. Boca Raron, Fla.: CRC Press. ANIMAIS EX6TICOs, SILVESTRES E DE ZOOLOGICOS Acceptable Field Methods in Mammalogy: Preliminary guidelines approved by the American SocietyofMammalogists. American SocietyofMammalogists.1987.J. Mammalogy68(4,5uppl):1-18. Diseases of Exotic Animals: Medical and Surgical Management.1983. Philadelphia: W. B. Saunders.1159 pp. Fur, Laboratory. and Zoo Animals. C. M. Fraser, J. A. Bergeron, and S. E. Aiello.1991. Pp. 976-1087, Part IV, in The McrckVeterinaryManual, 7th eel. Rahway, \ ,..: Merck and Co. Kirks CurrentVeterinaryTherapy Vol. Xl. Sma I Animal Practice. R. W. Kirk and J. D. Bonagura, eds. l 992. Philadelphia: W. B. Saunders.1388 pp. The Management of Wild Mammals in Captivity. L. S. Crandall. 1964. Chicago: University of Chicago Press. 761 pp. Pathology of Zoo Animals. L. A. Griner 1983. San Diego, Cal if: Zoological Society of San Diego. 608 pp. Restraint and Handling of Wild and Domestic Animals. M. E. Fowl er 1978. Ames: Iowa Statc University Press. 332 pp.

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Aptndice A - Bibliografia Selecionada - 117 Zoo and Wild Anhnal Medicine. M. E. Fowler, ad 1993. Philadelphia: W B. Saunders. 864 pp. AVES American Ornithologists= Union.1988. Report of Committee on Use of Wild Birds in Research.AUK.105(1,5uppl):lA-41A. Laboratory Animal Management: Wild Birds. NRC (National Research Council). 1977. A report of the ILAR (Institute of LaboraroryAnimal Resources) Committee on Standards, Subcommittee on Birds. 1977. Washington, D.C.: National Academy of Sciences. 116 pp. Physiology and Behavior of the Pigeon. M. Abs, ed. 19 83. Lmrdon: Academic Press. 360 pp. The Pigeon. W M. Levi.1974 (reprinted 1981).5umter, S.C.: Levi Puhli~lling. 66' PP Pigeon Health and Disease. D. C. Tudor.1991. Ames: Iowa State University Press. 244 pp. BEM-ESTAR Laboratory Animal Welfare Bibliography W. T Carlson, G. Schneider, J. Rogers, et al. 1 98 8. Beltsville, Md. D: U.S. Department of Agricul cure, National Agricultural Library 60 pp. Laboratory Animal Welfare Bibliography Scientists Center for Animal Welfare.1988. Bethesda, Md.: Scientist Center for Animal Welfare. 60 pp. Laboratory Animal Welfare. 1979-April 1989. C. N. Bebee, ed. 1989. Beltsville, Md.: U.S. Department of Agriculture, National Agricultural Library 102 pp. Laboratory Animal Welfare: Supplement 8. National Library of Medicine (NLM) Current Bibliographies in Medicine Series. Compiled by F. P. G luckstein. l 992. CBM No. 92-2. Washington, D C: U.S. Department of Health and Human Services. 86 citationsi 14 pp. (Available firm n Supr. of Does., U.S. G. P. O.). Scientific Perspective on Animal Welfare. W. J. Dodds and F. B. Or B!15, eds 1 982 New York: Acade m ic Press. 131 pp. CONTAMINANTES AMBIENTAIS Effect of environmental factors on drug metabolism: Decreased half-life of anripyrine in workers exposed to chlorinated hydrocarbon insecticides. B. Kolmodin, D. L. Azarnoff, and F. Sjoqvist.1969. Clin, Pharmacol. Tiler 10:638-642. Effect of essential oils on drug metabolism. A. Jori, A. Bianchert, and P. E. Prestini. 1969. Biochem. Pharmacol.18:2081-2085.

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118 - Manual sobre Culdados e Usos de Animals de Laboratorlo Effect of intensive occupational exposure to DOT on pherlvlhurazone and cortisol metabolism in human subjects. A. Poland, D. Smith, R. Kuntzman, M. Jacobson, and A. H. Conney 1970. Clin. Pharmacol. Ther. l l :724-732. Effect of red cedar chip bedding on hexobarbital and pentobarbital sleep time. H. C. Ferguson.1966. J. Phatm. Sci. 55:11 42- 1143. Environmental and Genetic Factors Affecting Laboratory Animals: Impact on Biomedical Research. Introduction. C. M. Lang and E. S. Vesell.1976. Fed. Proc. 35:1123-1124. Frozen Storage of Laboratory An imals. G. H. Zeilmaker, ad. 1981. Srutrgart: Gustav Fischer 193 pp. Environmental and genetic factors affecting the response of laboratory animals to drugs. E. S. Vescll, C. M. Lang, W J. White, G. T. Passananti, R. N. Hill, ;' L. Clemens, D. K. Lid, andW D.Johnson. Fed. Proc.35:1125-1132. Further studies on the sthnulation of hepatic mictosomal drug metabolizing enzymes by DOT and its analogs. L. G Hart and J. R. Fours. 1965. Arch. Exp. Pathol. Pharmakol.249:486-500. Induction of drug-metabolizing enzymes in liver microsomes of mice and rats by soirv-ood beddblg. E. S. Vesell.1967.5cience 157:1057- 1058. Influence on pharmacological experiments of chemicals and other factors in diets of laboratory animals. P. M. Newberne.1975. Fed. Proc.34:209-218. The provision of sterile bedding and nesting materials with their effect on breeding mice.G.PorterandW Lane-Petter 1965.J.Anim.Tech.Assoc.16:5-8. CUIDADOS COMANIMAIS DE LABORATORIO Animals for Research: Prblciples of Breeding and Management. W. l.anc-Petter, rd. 1963. NewYork:AcademicPtess.531 pp. The Biomedical Investigator=s Handbook for Researchers Using Animal Models. Fmlndarion for Biomedical Research.19R7. Washington, D.C.: Foundation for Biomedical Rts trash. 36 pp. The Experimental Animal in Biomedical Research. Volume 11: Care, Husbandry, and Well-being, An Overview by Species. B. E. Rollin and M. L. Kesel, eds. Boca Raron, Fla.: CRC Press. G Fidel hles for the Treatment of Animals in Behavioral Research and Teaching. Animal BehaviorSociety.1995. Anim. Behav 49:277-282. Handbook of LaboraroryAnimal Science, 2 Vol. P. Svendson and J. Hau.1994. Boca Raron, Fla.: CRC Press.647 pp. I.aboraroryAnimal Medicine. J. G. Fox, B. J. Cohen, and F. M. Loew, eds. l 984. New York: Academic Press.750 pp. I.aboratory A n unals: An An no tared B ibliography of I nformational Resources Covering Medicine-Science (I ncludulg Husbandry)-Technology. J. S. Cass, ed. l 971. New York: HaYner Publishing.446 pp.

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ApQndice A - Bibliografia Selecionada - 119 Laboratory Animals: An Introduction for New Experi men ters. A. A. Tuf e!; ed. l 987. Chichester: Wiley-lnrerscience.270 pp. Methods of Animal Experimentation. W. 1. Gay, ed. Vol. I, I J65, 382 pp.; Vol. 2, 1965, 608 pp.:Vol.3,1968,469 pp.: Vol 4, 1973, 384 pp.:Vol.5,1974,400 pp. Vol.6, 1981,365pp.Vol.7,PartA, 1986,256pp.;Vol.7,PartB, 1986, 269 pp.: Vol. 7, Part C, 1 989. 237 pp. New York: Academ ic Press. Pheromones and Reproduction in Mammals. J. G. Vandenbergh, ed. 1983. New York: Academic Press. 298 pp. Practical Animal Handling. R. S. Anderson and A. T B. Edney, eds 1991. El msford, N.Y: Pergamon.198 pp. Practical Guide to Laboratory Animals. C. S. F. Williams. 1976. St. Louis: C. V MosbY 207 pp Recent Advances m Germ-free Research. S. Sasaki, A. Ozawa, and K. Hashimoto, eds. 1981. Tokyo: Tokai Universiry Press 776 pp. Reproduction and Breeding Techniques for LaboratoryAnimals. E. S. E. Hafez, ed. 1970. Philadelphia: Lea and Febiger.275 pp. Restraint of Animals. 2nd ed. J. R. Leahy and P. Barrow. 1 953 Ithaca, N.Y: Cornell Campus Smre. 269 pp. The UFAWHandbookon the Care and Management of LaboraroryAnimals.6th ed. UFAW (Universities Federation for Anim al Welfare).1987. New York: Ch urch ill Livingstone. ENRIQUECIMENTO Environmental Enrichment Information Resources for Nonhuman Primates: 1987- 1992. National Agricultural Library, National Library of Med. icine, and Primate Information Center 1 992. Beltsville, Md.: National Agricultural Library. 105 pp. The Experimental Animal in Biomedical Research. Volume 11: Care, Husbandry, and Well-being, An Overview by Species. B. E. Rollin and M. L. Kesel, eds. Boca Raton, Fla.: CRC Press. Guidelines for developing and managing an environmental enrichment program for nonhuman primates. M. A. Bloomsmith, L. Y. Brent, and S. J. Schapiro.1991. Laboratory Animal Science,41 :372-377. Housing, Care and Psychological Well-Being of Captive and Laboratory Primates. E. F. Segal, ed. l 989. Park Ridgc, N.J.: Noyes Publications.544 pp. Monkey behavior and laboratory issues. K. Bayne and M. Novak, eds. Laboratory AnimalScience41:306-359. The need for responsive environments. H. Markowitz and S. Line.1990. Pp.153- 172 in The Experimental AnimaHn Biomedical Research. Volume 1: A Survey of

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120 - Manual sobre Culdados e Usos de Animals de Laborarririo Scientific and Ethical issues for Investigators, B. E. Rollin and M. L. Kesel, eds. Boca Eaton, Fla.: CRC Press. Nl H Nonhuman Primate Management Plan. O ffrlcc of Animal Care and Use. 1991. Bcthcsda, Md.: NIH, DHHS. Psychologlcai Well-BeingofNonhuman Primates. NRC (Nationa Research Council). 1996. A roper ofthe ILAR (InstituteofLaboratoryAnimal Resources) Committee on Well-being of Nonhuman Primates Washington, D.C.: National Academy Press. Research and development to enha n ce laboratory animal welfare. l 992. R. A. Wh itney ). Am. Vet. Med.Assoc.200(5):663-666. A review of environmental ail ri;hlltell t sit a egies lot sure to caged nonhuman primates. K, Fajzi, V Reinhardt, and M. D. Stnith.1989. Lab Animal 18:23-35. Through the Looking Glass. Issues of Psychological Well-Bcing in Captive Nonhuman Primates. M. Novak and A. J. Petto, eds. 1991. Washington, D. C.: American Psychological Association. ENSINO TECNICO E PROFISSIONAL Clinical Textbook for Veterinary Technicians. 3rd ed. D. M. McCurnin. 1993. Philadelphia: W. B. Saunders. 816 pp. Education and Training in the Care and Use of Laboratory Animals: A Guide for Developing institutional Programs. National Research Council.1991. A report of the institute of Laboratory Animal Resmlrces Committee on Educational Programs in Laboratory Animal Science. Washington, D. C.: National Academy Press. ] 52 PP The Education and Training of Laboratory Animal Technicians. S. Erichsen, W. ! I. van der Gulden, O. Hanninen, G. J. R. Hovell, L. Kallai, and M. Kherntnani. 1976. Prepared for rho international Committee on Laboratory; Animals. Geneva: World Health Organizauon. 42 pp. Educational Opportunities in Comparative Pathology-United States and Foreign Countries. Registry of Cotupararive Pathology, Armed Forces Institute of Pawhology. 1992. W tshillgton. D.C.: Universities Associated for Research and Education in Pathology 51 pp Labs. arorv Animal of edicinc: Guidelines for Education and Tr.tb~ing. ILAR (Institute of Laboratory AnUnal Resm~rces) Committee On Education 1979. ILAR News 22(2):MI-M26. Laboratm-y Animal Medicine and Science Audiotutorial Series. G. L. Van Hoosier, Jr, Coordinator. 1976-1979. Distributed by Health Sciences Learning Resources Center. University of Washington, Seattle. Lesson Plans: Instructional G uide for Technician Training.1990. AALAS (American Association for Laboratory Animal Science) Pub. No.90- 1. Joliet, 111.: American Association for LaboratorvAnimal Science.450 pp.

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Apendice A - 3iSliografia Selecionada - 127 The Marine Aquarium Reference: Systems and Invertebrates. M. A. Moe. 1989. Plantation, Fla.: Green Turtle Publications. 510 pp. The Principal Diseases of Lower Vertebrates. H. Reichenbach-Klinke and E. Elkan. 1965. New York: Academic Press.600 pp. PARASITOLOGlA Parasites of LaboratoryAnimals. R. J. Flynn.1973. Ames: Iowa State University Press. 884 pp. Veterinary Clinical Parasitology 6th ed. M. W. Sloss and R. L. Kemp.1994. Ames: Iowa State University Press. 198 pp. PATOLOGLAEPATOLOGLACLlNlCA Atlas of ExperimentalToxicological Pathology. C. Gopinath, D. E. Prentice, and D.!. Lewis.1987. Boston: MTP Press. 175 pp. An Atlas of Laboratory Animal Haematology. J. H. Sanderson and C. E. Phillips. 1981. Oxford: Clarendon Press. 473 pp. Blood: Atlas and Sourcebook of Hematology, 2nd ed. C. T Kapff and J. H. Jandl. 1991. Boston: Little and Brown. 158 pp. Clinical Chemistry ofLaboratot~ Animals W. F. Loeb and F. W. <;tuimby 1 988. New York: Pergamon Press. Clinical Laboratory Animal Medicine: An Introduction. D. D. Holmes.1984. Ames: Iowa State University Press 138 pp. Co o r Arias of Comparative Veterin ary Hematology. C. M. H awkey and T. B. Dennett. 1989. Ames: Iowa State University Press. . Color Atlas of Hem atological Cytology, 3rd cd. G. F. J. Hayhoe and R. J. Flemans. 1992. St. Louis: Mosby Year Book. 384 pp. Comparative Neuropathology J. R. M. Innes and L. Z. Saunders, eds. l 962. New York: Academic Press. 839 pp. Essen tials of Veterinary H ematology. N. C. Jain.1993. Philadelphia: Lea and Febiger 417 pp. Immunologic Defects in Lahoratmrr Animals. M. E. Gershwin and B. Merchant, eds. 1981. Vol I, 380 pp.; Vul. 2, 402 pp. New York: Plenum. An introduction to Comparative Pathology: A Consideration of Some Reactions of Human and Animal Tissues to Injurious Agents. G. A. Gresham and A. R. Jennings. 1962. New York: Academic Press 412 pp. Laboratory Pro files of Sm ail Animal D iseases. C. Sodikoff 1981. San ta Barbara, Calif: American Veterinary Publicanons. 215 pp.

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128 - Manual sobre Cuidados e Usos d. Animals de Laboracdrio Outline of Veterbrary Clhnical Pathnlogv. 3rd ed. M. M. Benjamin.1978. Ames: Iowa State University Press 35' pp. Pathology of Laboratory Animals. K. Ben irscilke, F M. Gamer, and T C. Jones.1978. Vol. 1.1050 pp.; Ml 2, 7 171 pp. NewYork: SpringerVerlag. The Pathology of Laboratory Animals. W. E. Ritelin and J. R. McCoy, eds. 1965. SpringErekl, 111.: Charles C. Thomas. 43G pp. The Problems of LaboraroryAnimal Disease. R. J. C. Harris, ed.19G2. NewYork: Academic Press.2G5 pp. Roentgen Techniques in Laboratory Animals. B. Felson.19G8. Philadelphia: W. B. Saunders AS pp. Schalr.l=s Veterinary Hematology. 4th ed. O. W. Schalm and N. C. Jam. 1986. P hiladel phia: Lea an d Feb iger. l 221 p p. Techniques of Veterinary Radiography, 5th ed. J. P. Morgan, cd. Ames: Iowa State University Press. 482 pp. VeterinaryClinicalPathology.4thed. E. H. Coles.198G. Philadelphia:W B. Saunders. 486 pp. Veterinary Patholog,v; 5th ed. T. C. Jones and R. D. Hunt.1983. Philadelphia: Lea and Febiger.1792 pp. PERIODICOS Advances in Veterinary Science. Vol. I - 12.1953- 1968 New York: Academic Press. Advances in Veterinary Science and Comparative Medicine (annual, continuation of Advances in Veterinary Science). New York: Academic Press. The Alternatives Report (bimonthly). North Grahton. Ma.: Center for Animals of Public Policy, Tufts University. AmericanJournalofPadhology (monthly). Baltimore: American Society for Lrvestigative Pathology American Journal of Primatology (monthly). N en York: Wiley Liss. American Journal of Veterinary Research (monthly). Schaumburg, 111.: American Veterinary Medical Association. Animal Models of Human Disease (A Handbook). Washington, D.C.: The Registry of Comparative Pathology, Armed Forces Institute of Pathology. The Animal Policy Report: A Newsletter on Animal and Environmental issues (quarterly). North Grafton, Ma.: Center for Animals or Public Policy, Tufts University. Animal Technology (semiannual formerlyThe institute of Animal Technicians Journal). Cardiff U. K.: The ins brute o f An imal Techn icians. Animal V ei8are (quarterly). Porters Bar, Herts, U.K.: Universities Federation for Anima Welfare. Animal Welfare information Center Newsletter (quarterly). Beltsville, Md.: Animal Welfare Information Cenreo

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Apendice A - Bibliograha Seiecionada 129 Animal Welfare Institute Quarterly Washington, D.C. Animal Welfare Institute ANZCCART News (quattedy). Glen Osmond, Australia: Australian and New Zealand Council for the Care of Animals in Research and Teaching. Canadian Association for LaboratoryAnimal Medicine Newsletter Canadian Association for LaboratoryAnimal Medicine. Canadian Association for Laboraton Animal Science Newsletter. Canadian Association for LaboratoryAnimal Science. Comparative Immunology, Microbiology and Infectious Diseases: International Journal for Medical andVeterinary Researchers and Practitioners (quarterly). Meter, U.K.: Elsevier Science. CompatauvePadhologyBulletin (quarterly).Washington, D.C.: Rer,str of Gor.pararive Pathology, Armed Forces Institute of Pathology. Contemporary Topics (bimonthly). Cordova, Tenn.: American Association for LaboratoryAnimal Science. Current Primate References (monthly). Searde: Washington Regional Primate Research Cell ret, Un iversity of Washi ngton. FoliaPrimatologica, InternationalJournalofPrimatology(6-weekly). Basel:S. Karger Humane Innovations and Alternatives (periodical). Washington Grove, Md.: Psychologists for the Ethical Treatment of Animals. ILAR Journal (quarterly). Washington, D.C.: Institute of Laboratory Animal Resources (ILAR), National Research Council. International Zoo Yearbook (annual). London: Zoological Society of London. The Johns Hopkins Center for Alternatives to Animal Testing Newsletter (3 isses per year). Baltimore: CenterforAlternatives roAnimalTesting. Journal of Medical Primatology (bimonthly). Copenhagen, Denmark: Munksgaard International Publishers. Journal of Zoo and Wildlife Medicine (quarterly). Lawrence, ICans.: American Association of Zoo Veterinarians. Lab Animal ( 11 issues per year). New York: Nature r .:1.1,; ..: LaboratoryAnimal Science (bimonthly). Cordova, Tenn.: American Association for Laborarnr Animal Science. Mailingaddress: 70Timber Creek Dr. Cordova,Tn 38018. La borarory Animals (quarterly). Journal of the Labora Or Animal Science Association. London: Laboratory Animals Ltd. Mailing address: The Registered Office, Laboratory An im als Ltd. , I Wimpole Street, London W l M 8AE, United Kingdom . Laboratory Primate Newsletter (quarterly). Providence, R.l.: SchrierResearch Laboratory, Brown University. Mouse News Letter (semiannual). Available to the western hemisphere and Japan fro m The Jackson Laboratory, Bar Harbor, ME 04609; available to other locations from Mrs. A. Wilcox, MRC Experimental Embryology and Teratology Unit, Woodtnansteme Road, Carshalton, SurreySM5 4EF, England,

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130 - Manual sobre Cuidados e Usos de Animais de Laborardrio OurAnimal Wards. Washington, D.C.: Wards. Primates: AJm~rnal of Primatology (quarterly). Aichi, Japan Japan Monkey Centrc Rat News Letter (semiannual). Available fi om Dr D. V Cramer, ed., D epartnlCllt of Pathology, School of Medicine, UniversityofPittsburgb, Pittsburgh, PA 15 2 61. Resource. Ottawa, Ontario, Canada: Canadian Council on Animal Care. SCAW Newsletter (quarterly). Bethesda, Md.: Scientists CenterforAnunalWelfate, Zeitschrift fuer Versuchstierkunde, Journal of Experimental Animal Science (irregular, approximately G issues per year). Jena, Germany: Gustav Fischer Verlag. Zoo Biology (bimondhly). New York: Wiley-Liss. Zoological Society of London Symposia (annual). Oxford: Oxford Science. PLANEJAMENTO E CONSTRUCAO DE BIOTERIOS Approaches to the Design and Development of Cost-Effective Laboratory Animal Facilities.1993. Canadian Co uncil on An imal Care (CCAC) proceedings. O trap a, Ontarion, Canada: CCAC. 273 pp. Comfortable Quarters for Laboratory Animals. rev. ed. l 979. An im a ~VJelfau e Institute. Washington, D.C.: Animal Welfare institute. 108 pp. Control of the Animal House Environment. T McSheely, ed. 1976. London: Laboraror Animals Ltd. 335 pp. Design of Biom edical Research Facilioes. D. G. Fox, ed ' 981. Cancer Research Safety Monograph Series, Vol. 4. NIT Pub. No. 81-2305. Washington, D.C.: U.S. Deparmmenr of H ealth and Human Services. '06 pp. Design and Optimization of Airflow Patterns. S. D Reynolds and H. Hughes.1994. LabAnimal. 23(9):46-49. Estimating heat produced by laboratory animals. N. R. Brewer. 1964. Heat. Piping Air Cond. 36:139-141. Guidelines for Construction and Equipment of Hospitals and Medical Facilities, 2nd ed. 1987. American institute ofArchitects Committee on Architecmre for Health. Washington D C.: American institute of Architects Press. l l l pp. Guidelines for Laboratory Design: Health and Safety Considerations. L. J. DiBerardinis, J. S. Baum, M. W. First, G.T Gatwood, E. F. Groden, and A. K. Seth. 1993. New York:JohnWileyo~Sons.514pp. HandbookofFacilities Planning. Volume 2: LaboratoryAnimal Facilities. T Ruys, ed. 1991. New York: Van Nostrand Reinhold.422 pp. Laboratory Animal Houses: A G uide to the Design and Plam~ing of Animal Facilities. G. Clough and M. R. Gamble. 1976. LAC Manual Series No. 4. Carshalton, Surrey, U.K.: LaboratoryAnimals Centre, Medical Research Council. 44 pp. Laboratory Animal Housing. N RC (National Research Com~cil). 1978. A report of thc ILAR (Institute of LaboratoryAnimal Resources) Committee on Laboratory Animal Housing. Washington, D.C.: National Academy of Sciences.220 pp

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Apendice A - Bibliografia Selecionada - 131 Structures and Environment Handbook. 11 th ed. rev. Midwest Plan Service. 1987. Ames: Midwest Plan Service, Iowa State University. The Use of Computational Fluid Dynamics For Modelbrg Air Flow Design in a Kennel Facility H. C. Hughes and S. Reynolds.1995. Cm~temp Topics 34:49-53. PRIMATAS NAO-HUMANOS Aging in Nonhuman Primates. D. M. Bowden, ed. 1979. New York: Van Nostrand Reinhold. 393 pp. Thc Anatomy of the Rhesus Monkey (Macaca mulatto). C. G. Hartman and W. L. Strauss, Jr., eds. 1933. Baltimore: Williams and Wilkins. 383 pp. (Reprinted in 1970 by Hafner, New York). An Atlas of Cmllparati\ e Primate Hematology. H. J. H user 1970. New- York: Academic Press. qO5 pp. Behavio r and Pathology of Aging in Rhesus Monkeys. R. T Davis and C. W. Leathrus, eds. 1985.NewYork:AlanR.Liss, Brerdurg Simians for Developmental Biology. Laboratory An Hal Handbooks G. F T Perkins and P. N. O=Donoghue, eds. 1975. London: Laboratory Animals Ltd. 353 pp. Captivity and BehaviorCPrimares in Breeding Colonies, Labor Iml ~ and Zm !. J Erwin, T. L. Maple, and G. Mitchell, eds. l 979. New York: Van Nostrand Reinhold. 286 pp. The Care and Management of Chimpanzees (Pan troglodytes) in Captive Environments. R. Fulk and C. Garland, eds. 1992. Asheboro: North Carolina Zoological Society. Compatarive PaDhology in Monkeys. B. A. Lapin and L. A. Yakovleva.1963. Springfield, 111.: Charles C. Thomas. 272 pp. Diseases of LaboratoryPrimates.T C. Ruch.1959. Phi adelphia: W B. Saunders. 600 pp. A Handbook of Living Primates: Morphology, Ecology, and Behaviour of Nonhuman Primates. J. R. Napier and P. H. Napier 1967. London: Academic Press.456 pp. HandbookofSquirrelMonkeyResearch. L.A.Rosenblum and C. L. Coe, eds. 1985. NewYork: Plenum Press. SOI pp. Labo raron; An i m al Management: Nonhuman Pri m ares. ILAR (Institute of Laboratory Animal Resources) Committee on Nonhuman Primates, Subcommittee on Care and Idse. 19&0. ILAR News 23(2-3):PI-P44. Laboratory Primate Handbook. R. A. Whitney, Jr, D. J. Johnson, and W. C. Cole. 1973. New York: Academic Press. 169 pp. Living New World Monkeys (Platyrrhini). Vol. I. P. Hershkovitz. 1977. Chicago: University of Chicago Press. 117 pp. The Macaques: Studies in Ecology, Behavior, and Evolution. D. G. Lindburg.1980. New York: Van Nostrand Reinhold. 384 UD.

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132 Manual sobre Cuidados e Usos de Animals de Laboratbrlo Macaca m ulatta. Management of a Laboratory Breeding Colony D. A. Valerio, R. L. Miller,J. R. M. Innes, K. D. Courmey,AJ. Pallotta, and R. M. Guttmacher 1969. NewYork:AcademicPress.140pp. Nonhuman Primates in Biomedical Research: Biology and Management. B T Bennett, C. R. Abee, and R. Henrickson, eds.1995. New York: Academic Press. 428 pp. Padmlo~ of Simian Primates. R. N. T W Fiennes, ed. 1972. Parr 1, General Padhology; Part 11, Infectious and Parasitic Diseases. Basel: S. Karger Primates: Comparative Anatomy and Taxonomy Vol. 1-7. W. C. O. Hill, ed. 1953-1974. New York: Interscience Publishers. The Primate Malarias. G. R. Coatney, W. E. Collins, IvfcW Warren, and P. G. Contacos. 1971. Washington, D.C.: U. S. Department of Health, Education, and Welfare. 366 pp. Zoonoses of Primates. The Epidemiology and Ecology of Simian Diseases in Relation to Man. R. N. T. W. Pieces 1967. London: Weidenfeld and Vicobon. 190 pp. REFERENCIAS GERAIS Biologv Dara Book. 2nd ed. P. L. Altman and D S. Dittmer. Vol. 1, 1971, 606 pp.i Vol 2, 1973, 1432 pp.; Vol. 3, 1974, 2123 pp. Bethesda, Md.: Federation of American Societies for Experimental Biology. Disinfection, Sterilization, and Preservarion,4dh cd. S. S. Block, ad. 1991. Philadelphia: Lea and Febiger. 1162 pp. A GuidedTour of VeterinaryAnatomy: Domestic Ungulates and Laboratory Mammals. J. E. Smallwood.1992. Philadelphia: W B. Saunders. 390 pp. Health Benetirs of Animal Research. W. 1. G ay 1 985. Washington, D.C.: Foundation for Biomedical Research. 82 pp. The 1- rev-: :lhle Bond: Examining scientist-animal interactions H. Davis and D. Balfour, eds. 1992. Campridge: Cambhdge University Press. Jones'Animal Nursing.5th ed. D. R. Lane, ed.1989. Oxford: Pergamon Press.800 pp. LaboratoryAnimals.A.A. Tuffery.1995. London:JohnWiley Science, Medicine, and Animals. National Research Council, Committee on the Use of AnUnals in Research. 1 99 1. Washington, D.C.: National Academy Press. 30 Use of LaboratoryAnimals in Biomedical and Behavioral Research. National Research Council and InstiruteofMedicine, Committee on the UseofLaboratoryAnimals in Biomedical and Behavioral Research. 1988. Washington, D.C.: National Acadetny Press.102 pp. Virus Diseases in Laboratory and Capove Animals. G. Darai, ed. l 988. Boston: N4hoff. 568 pp.

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Apendice A - Bibliografia Selecionada - 133 RISCOS BIOLOGICOS EM PESQUISAANIMAL Animal-Associated Human Infections. A. N. V elnberg and D.). Weber.1991.1nfectious Disease Clinics of North America, 5: ] - 181. Biohazards and Zoonotic Problems of primate Procurement, Quarantine and Research. M. L. Simmons, ed. 1975. Cancer Research Saiery Monograph Series, Vol. 2. DHEW Pub. No. (i\ lH) 76-890. Washingron, D.C.: U.S. Dcparrmenr of Hea rh, Education, and Welfare. 137 pp. Biological Saferv Manual for Research Involving Oncogenic Viruses. National Cancer Instirute. 1976. DHEW Pub. No. 76- 1165. Washingron, D C: U.S. Department of Health, Education, and Welfare. Biosafery in Microbiological and Biomedical Laborarories.3rd ed. Centers for Disease Control and National Institutes of Health. 1993. DHHS Pub. No. (CDC) 93-8395. Washington, D.C.: U.S. Department of Health and Human Services. 177 pp. Biosafety in the Laboratory: Prudent Practices for Handling and Disposal of Infectious Materials. Commirree on Hazardous Biological Substances in the Laboratory, National Research Council.1989. Washington, D.C.: National Academy Press. 244 pp. Cl assit;ca rion of Etiologic Agents on the Basis of Hazard.4th ed. U.S. Public Health Service Ad Hoc Committee on the Safe Shipment and Handling of Etiologic Agents. 1974. Washington, D.C.: U.S. Department of Health, Education, and Welfare. Code of Fede M I Regularions.1984.Title40; Parr 2 60, HazardousWasreManagement System: General; Part 261, Iden tificarion and Listing of H azardous Waste; Part 262, S[ar[dards Applicable to Generators of Hazardous Waste: Parr 263, Standards Applicable to Transporters of Hazardous Waste; Part 264, Standards for Owners and Operators of H azardo us Waste Treatment, Storage, and D isposal Facilines; Part 265, Interim Status Standards for Owners and Operators of Hazardous Waste Treatrnenr, Storage, and Disposa Facilities; and Pi r[ 2-!?, EPAAdministered Permit Programs: The Hazardous Waste Permit Program. Washingmn, D.C.: Of }ice of Federal Register (Parr 260, updated April 1994; 261 and 270 updated August, 1 994; 264 and 265 updated June, 1994; 262 and 263 updated 1993). Design Criteria for Viral Oncology Research Facilities. National Can cer be stiru [c. By - 5 DHEW Pub. No. (NIH)76-89 1. Washington, D.C.: U.S. Deparrment of Health, Education, and Welfare. 24 pp. Diseases Transmitted From Animals to Man. Ah ed. W. T Hubbert, W. F. McCulloch, and P. R. Schnurrenberger, eds.1974. Springfield, 111.: Charles C.Thomas. 1206 PP

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134 - Manual sobre Culdados e Uses de Animals de Laboratbrlo Guidelines for Carcinogen Bioassay in Small Rodents. J. M. Snrlrag, N. P Page, and U. Saffiotti. 1976. DHEW Pub. No. (NIH) 76-801. Washington, D.C.: U.S. Department of Health, Education, and Welfare. 65 pp. G Sidelines for Research Involving Recombinant DNA Molecules. National Institutes of Health.1984. Fed. Regist.49(227):46266-46291. Guidelines on Sterilization and High-Level Disinfection Methods Effective Against Human Immunodeficiency virus (HIV). 1988. Geneva: World Health Organization. l l pp Industrial Biocides. K. R. Payne, ad. 1988. NewYork: Wiley 118 pp Laboratory Safety for Arboviruses and Certain Other Viruses of Vertebrates. Subcommittee on Arbovirus Safety, American Committee on Arthropod-Borne Viruses. 1980. Am. ]. Trop. Med. Hyg. 29: 1359-1381. LaboratorySafeqMonograph: A Supplement to the NIH Guidelines for Recombinant DNA Research. National Institutes of Health. 1979. Washington, D.C.: U.S. Department of Health, Education, and ~Velfarc. 227 pp. National Cancer Institute Safety Standards for Research Involving Oncogenic Viruses. National Cancer Insrirure. 1974. DH EW Pub. No. (NIH) 78-790. Washington, D. C.: U.S. Department of Health, Education, and Welfare. 20 pp. NIH Guidelines for the Laboratory Use of Chemical Carcinogens. National Institutes of Health.1981. NIH Pub. N a. 81-2385. Washington, D.C.: U.S. Department of Health and Human Services. I S pp. An O u Al ine of the Zoonoses. P. R. Schnurrcnberger and W. T. Hubert. 1981. Ames: lowaState ~~ n ivc rsit ~ Press. 15 8 pp. Prudent Practices in the Laboratory: Handling and Disposal of Chemicals. National Research Council. 1995. A report of the Committee on the Study of Prudent Practices for Handling, Storage, and Disposal of Chemicals in Laboratories. Washington, D.C.: National Academy Press. The Zoonoses: InfectionsTransmitted from Animals to Man. J. C. Bell, S. R. Palmer, and J. M. Payne.1988. London: EdwardArnold 241 pp. Zoonosis Updarcs from the Jour rlal of the American Veterinary Medical Association. 1990.5chaumbutg, 111.: American Veterinary Medical Association Rio pp. ROEDORES E COELHOS Anatomy and Embryology of the Laboratory Rat. R. Hebel and M. W. Strom berg. 1986. Worthsee, stare: BioMed. 271 pp. Anatomy of the Guinea Pig. G. Cooper and A. L. Schiller 1975. Cambridge, Mass.: Harvard U niversiry Press. 417 pp. Anatomy of the Rat. E. C. Greene. Reprinted 1970. NO York: HaDner. 370 pp. Bensley=s Practical Anatomy of the Rabbit. 8th ed. E. H. Craigie, cd. 1948. Philadelphia: Blakistmr.3Y I pp.

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Apendice A - Bibliografia Selecionada - 135 The Biology and Medicine of Rabbits and Rodents. J. E. Harkness and J. E. Wagner 1989. Philadelphia: Lea and Febiger. 230 pp. The Biology of the Guinea Pig. J. E. Wagner and P J. Manning, eds. l 976. New York: Academic Press. 317 pp. Biology of the House Mouse. Symposia of the Zoological Society of London. No. 47. R. !. Berry, ad 1981. London: Academic Press. 715 pp. TheBiologyoftheLaboratoryRabbit. S. H.Weisbroth, R. E. Flatt, andA. Kraus,eds. 1974. New York: Academic Press. 496 pp. The Brattlchoro Rat. H. W. Sokol and H. Valtin, ads. 1982 Ann. N.Y. Acad. Sci. 394:1 -R28. Common Lesions in Aged B6C3 F (CS7B L/6N x C3 H/HeN) F and BALB/cS tCrlC3 H / Nctr Mice. Syllabus. Registry of Veterinary Pathology, Armed Forces Institute of Pathology.1981. Washington, D.C.: Armed Forces Institute of Pathologv 44 pp. Common Parasites of Laboratory Rodents and Lagomorphs. Laboratory Animal Handbook. D. Owen 1972. London: Medical Research Council. 140 pp. Complicatim~s of Vira and Mycoplasmal Infections in Rodents to Toxicology Research andTcsting. T E. Hamm, cd 1986. Washington, D.C.: Hemisphere Publishing. 191 RP Definition, Nomenclature, and Conservation of Rat Strains. ILAR (Institute of Laboratory Animal Resources) Committee on Rat Nomenclature.1992. ILAR News 34(4): 51-524. A G aide to Infectious Diseases of Guinea Pigs, Gerbils, Hamsters, and Rabbies. NRC (.\ aom~ai Research Council).1974. A report of the ILAR (Institute of Laborarory Animal Resources) Committee on LabotatoryAnimal Diseases. Washington, D.C.: Na til:ma I Academy of Sciences 16 pp. Guidelines for the Well- Being of Rodents in Research. H. N. G urtman, ed. 1990. Bethesda, Md.: Scientists Cen ter for Animal Welfare. 105 pp. The Hamster: Reproduction and Behavior. H. l. Siegel, ed. l 985. New York: Plenum Press.440 pp. Handbook on the Laboratory Mouse. C. G. Crispens, Jr 1975. Springfield, 111.: Charles C. Thomas. 267 pp. Histological Adas of the Laborarory Mouse. W D. Gude, G. E. Cosgrove, and G. P. Hirsch.1982. NewYork: Plenunt.151 pp. Infectious Diseases of Mice and Rats. NRC (National Research Council).1991. A report of the ILAR (Institute of Laboratory Animal Resources) Committee on Infectim~s Diseases of Mice and Rats. Washington, D.C: National Academy Press. 397 pp. Laboratory Anatomy of the Rabbit.2nd ed. C. A. McLaughlin and R. B. Chiasson. 1979. Dubuque, lowa: Wm. C. Brown.68 pp. Laboratory Animal Management: Rodents. NRC (National Reseawh Council). In press. A repo rt of the ILAR (Ins titute of Laborato ry An imal Resources) Committee m~ Rodents. Washington, D C.: National Academy Press.

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136 - Manual sobre Cuidados e Usos de Animals de Laboratbrlo A Laboratory Guide to the Anatomy of the Rabbit. 2nd ed. E. H. Craigie. 1966. Toronto: University of Toronto Press. 115 pp. Laboratory Hamsters. G. L. Van Hoosier and C. W. McPherson, eds. 1987. N ew York Academic Press. 45G pp. The Laboratory Mouse: Selection and Management. M. L. Simmons and J. O. Brick. 1970. EnglewoodCliffs, N.J.: Prentice-Hall. 184 pp. The Laboratory Rat. H. J. Baker, J. R. Lindsey, and S. H. Weisbroth, eds. Vol. l, Biology and Diseases,1979,435 pp.; Vol. 11, Research Applications,1980,276 pp. New York: Academic Press. The Mouse in Biomedical Research. H. L. Foster, J. D. Small, and J. G. Fox, eds. Vol. 1, History, Genetics, and Wild Mice,1981,306 pp.; Vol. 11, Disease,1982,449 pp.; Vol, 111. Normative Biology, immunology, and Husbandry,1983,447 pp.; Vol. IV, Experimental Biology and Oncology, 1982, 561 pp. New York: Academic Press. The Nude Mouse in Experimental and Clinical Research. J. Fogh and B. C. Giovanella, eds. Vol. I, 1978,502 pp.; Vol. 2, 1982, 587 pp. New York: Academic Press. Origins of I nbred M ice. H. C. Morse 111, ed. 1979. NewYork:AcademicPress.719 PP Pathology of Aging Rats: A Morphological and Experimental Snudy ofthe Age Associated Lesions in Aging BN/B 1, WAG/Rij, and (WAG x BN) F Rats. J. D. Burek.1978. Boca Raton, Fla.: CRC Press '- 30 pp. Pathology of As in,, Syrian Ha asters. R. E. Sehlrl ids, R. L. Eason, G. B. Hubbard, J. T. Young, and D. L. Eisenbrandt.1983. Boca Raton, Fla.: CRC Press. 272 pp. Pathology of Laboratory Mice and Rats. Biology Darabook Editorial Board. 1985. Bethesda, Md.: Federation of American Societies for Experimental Biology 488 Pi Pathology of the Syrian Hamster. F. Homburger, ed. l 972. Progr. Exp. Tumor Res. 16:1 -637. Proceedings of the Third international Workshop on Nude Mice. N. D. Reed, ed. 1982. Vol. I, invited Lectures/lnfection/lmmunology, 330 pp.; Vol. 2, Oncology, 343 pp. New York: Gustav Fischer. The Rabbit: A Model for the Principles of Mammalian Physiology and Surgery. H. N. Kaplan and E. H. Timmons.1979. New York: Academic Press. I G7 pp. Research Techniques in the Rat. C. Petty.1982. Springfield, 111.: Charles C. Thomas. 3G8 pp. Rodents and Rabbits: Current Research issues. S. M. No iemi, J. S. Venable, and J. N. G uttman, eds. l 994. Bethesda, Md.: Scien fists Center for Animal \ Velfare. 81 pp. Viral and Mycoplasmal Irthections of Laborarory Rodents: Effects on Biomedical Research. P. N. Blatt.1986. Orlando, Fla.: Academic Press.844 pp.

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Apendice A - Bibliografia Selecionada - 137 TAMANHO DA AMOSTRA E DESENHO EXPERIMENTAL Animal welfare and the statistical consultant. R. M. Engeman and S. A. Shumake. 1993. American Statistician 47(3):229-233. Appropriate animal numbers in biomedical research in light of animal welfare considerations. M. D. Mann, D. A. Grouse, and E. D. Prentice.1991. Laboratory Animal Science, 41 :6-14. The Design and Analysis of Long-Tenn Animal Experiments. J. J. Garr, D. Krewski, P N. Lee, etal.1986. Lyon: InternationalAgencyforResearch on Cancer 219 pp. Power and Sample Size Review. T J. Prihoda, G. M. Barnwell, and H. S. Wigodsky 1992. Proceedings of the 1992 Primary Care Research Methods and Statistics Conference. Contact: Dr. T Prihoda, Department of Pathology, University of Texas Health Science Center, San Antonio, TX 78284.