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6
>t~nil-l~i'll
Olik Oth~At1_1~1 L ~ ~ R11~: }> ~ 7 (Drozdowicz et al. 1990; Jelinek 1971:
Lardi et al. 1982: f'rasad ct al. J978; Sanhouri et al. 1989; Tuli et al.
1995; Wallace 1976).
1~RD7~;~: ~ ~ ~ 1_, tJr to ~V'~-.;'~/'~J.~"~",':
h iT$)l~:hO~t7~t-~-l], Th~ 2-F)~l~S-~1~3~. IBM
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7. 2 ~~)(JJ~75~:E~g~bj`:lPlu,.~l- ~ A, him, iT~tJg~h/`Jl:RTt~ /~r'i:
374 611. !~RI~SnIfrin.~2.~: ~ Abut -, ~~f)J~I_~(li
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Th~-~ ~) ~ ~ ~.~ < _ ~ t,$ ~ 6. ~I_ r,JJ~ '~ ~9I-~SiJf~ t2~-
$f rJ ~,~ii,
Bordetelle hronchisepticald:, 7it r~tg:~7~ L 13:~- < ~ 8, ~i~=c
z ~ I:l]~.)~Pl-P~i~.~;~ 2~ (Manning et al. 1984).
)~71J? l'<~.fitll:~(~1i~i~.), T7l)h~lRlk-~ - P~. i~T~lr41J~-~
~i~ 1~. ~ (~? t6X3~.-: S3~l ~ f~lJ ~ /~3JPW~ nn i~simian hemorrhagic
fever (Palmer et al. 1968) ~;O:3ti~;~;~*~!P>7 (Hirsch et al
1991; Murphey G>rb et al. 1986) It, T7 ) hIZ./ /] f;~Jilt~-~6t
tt:~ ~t`. T-,T~ild:~ti l6.
Il~l :~.~k`_~11 ~K: ~ ~ih1~< :, Xlli-9,3 Pr ~ ~ :~. ~ ~ ~ r~j/,-, t75-~ :. f~ll:,i'
Herpesvirus tamarir us I t I) ~ ~'iU Sairriri sciureus /: f; ~ ItJr''~ ~ ~ b~, 3
+~7PA otus trivirgatus ( Hunt and Melendez 1966) .i ~ ~ ~ ~ ~ ~—
t: ~? ~ ~$ ~ I) ~Saguirus oedipus, S rigrKollis (llolmes et al. 1964;
Melnick et al. 1964) 1:1ilX~Pj5i.-~3~ iL ~ t_ :, t.
;~c ht -~< ~ ~ 7 ~ ~F~rfi< }, ~ 7 2. tPh~JJ ~ ~fit t ^~l ~ r,~
b. ~:Er~jb/~t§~;:t /]', I-RJ -~1O/~lLS3piti~t\~) Lti
. Sf~J<~. 7, hP~i~1lik-~4l~717~, 7~hrF~. 93t\
Pasteurella multocida, ~hhF~itP>o Cercopithecire herpesvirus 1 (IH?.
Herpesvirus simiae) ji ..t ll'7'? ~Mycopla ma hyotneu11~0riael ~ l~-.~.l 6.
62
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7).,, I, ~L~r, L Rid'
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7. ~h~+!4l~f~i~+ll:34~h~v~z~o~~~: 71_, ~R'7~.~
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hqi~JJh'-7i!iR~TL_~ ~ t ho ~ 7, ~
},¢,¢¢~¢~¢ ~r-,6cl~/ ~¢~1
~ ~ Jv~.-~h :~5't 7~ t7~f TV! ~ t~ ~ t]:3~*1~:; 45 7~. ~ hll~¢ !
tit~,i:~{lii~4~¢~1_~iK~=bO~, ~ l~<2~SiT~~I~~¢il;
(polymerase chain reaction: PCR) 1_ at 7~ DNA¢ Or I. EibJ*~iii~'; It's
~¢ ,p:,r~.l'~_~:,<~l~, ~hb¢~-'~)Z~ ~ l:'. -!T~¢¢i11-F*~ ~ "47
I) ~—>. l+5l:il¢¢~.l:(J<¢ 11k¢ 'L~,~lk1ll:~, It~l~l434ir747l~7~¢ hash
j¢¢ r .i is, ~ rr —Ditty t7)'}>~ (Nicklasetal.1943). flAJ/~J:h~ll]
;~¢¢ ¢~i¢¢e-t7~¢-I], m~3~Miii~ (mouse-antibody-production:
MAP) =ii~t!~. 7 ~ ¢ ~*i=lRAP¢-~IQ~-4~47~?—~~*i=!EHAP~>
fiEh: (de Souza and Smith 1999; NRC l99lc) :t~G—~ir~lza
fR'i¢ ¢-ij-L~i~. ~q~¢ ¢ ~—_i)', ~,~/j~> jMq it~ii~t —
in id ilk 1: ~ ~)dih~0'£~bil~r iii 4: !:1_ at < it.-~;) hi}. 'I
ti-—~.Rti-~ (AWAY "him, ~=9j~', ~~bj~ ~I(j,i~,UR,), _hG~:
IRISES 1-li ~ ~ Awls, ~r77~)I;q~i:< 3J]~)~il- ~ ~ ~ . ;:
6 6~1~$~--~6 :~_; ~ ', ~rl~1~- it_—/~
bestir l_ lie lo lJ led Lt 7D~ (Broun and Schofield 1994: 1':-. -.;n et al.
993).
1) 6 t_ :,l+.~ik t`~ 6~h9~-i-iTTiil: ~ (_ ~ ~ A, —t.,i~
J£~rhOt-i!kY)~), to i, - ijjRi/lf:Tt;ND: i~iiir!.~*. i Mini
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'I.
he, D4-3~f~f, I> I, 4~ r~ ~ ~ ~ ~ i£~1~ 10K~:~-~)J Fly. IT ~ t ~~,
,¢5~hO d: Amp-, I',, Oh: b.~`fr,Lm;~ ~ ~1~?—~ 7~ >--, IF L V~ F-{'T~
LIT 1- ~ it t In t I- 1~ ~ (Chaffee 1974: N\Thlgfield 1979). (31 53.~r
*. ~ .~ L t its, 4~-Q'`~'r.,.ti-/.k-~ <~6 It'd,
ifq~jjl ~ ;5~ l) ~ a, ~ ~——>7'biL:~-C~7,-~. fTlJ<,J'6 L~fqi_i31lt,~
· t ~,:,~, ~~'l~`J t~'J$.''-~. ~b'y~ · f',1,fi~3~. If
It ~~3ihl'7~-t'i:~t'(~-~. 'X~Of~q!~j Jo, T~rr~.~h
'` Lt ~ ~—- :~il-ti:~?~itl:, I) (ASR 1989), (31'3 brrl-J: fir
/74~'if~1:~ -a. "I'," riots;-13hlJJi~llL13)lJ to,
r Mom ji -; ~t"I'~~lCii~G9'~tr~1~1-~. :: i: L t>~,~ L. ~ ~ ~ /;~
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f1T~,?jTI:i.~, f~,'':K r if—~ ~ I: ~l,b3 ~ I Or ~ ~ ~ `T ~ ~ Y ~~ To ~ ).
/3~3~Q~q69~t4i~$-io7~ ~ f T: 3 _ I;J Hi imps_ Item Its- ZZ-ilb-~
~ il~ili~t!li J ~Jrii}i~3 4i~f~lo~V~:~:r~ a. Liar- ~ L lo L lofiV3 ~tiT~3f3
Tilts. T*3*~l~r~ul0~.r~.
3~TTMq-l fiti6 LtL~> ', it i+~fF7b`Jt Lt Ace. Lo
L, i Go J: j ft~l- io~f~-~t 31~- L Or, Mqfb~'l:~Tr~t~-~:
j ~ ~ I- ~ ~ . ~ ~ J: j 7~o'~iTi ~ )- ~ t ~ l+ ~ LAgthil~llffi l: t ~ t ~ -, r: ~
~~I-~ ~ r ~ ~ ri~ F' all jlil]l ~ t_ ~ / lo, CITE liri TM[TI)) t' ~ r ~ ~ (C~lllliffe
if i ~ a IT er ] 9 9.3 ) . J:~^biL't_ i). ~ T i k~fJm L t_ J . 1~] r j tote
65
4Q~I~'~ I_lXi1- to I
/ t ~ bow jock--- ~ ~ t~ (Schonholtz 1976). f I[j;T$1_ A ~ ~ T'fl*' ;, ~ IH-$I)4(
Tot': (Belkin 1992: McWilliams 1976). (tt~;htbi-y~TU
hq~ |,., 2'O~ Throw )~ ~ tact, ffqolll~: J: ~ ~ sack 6. lilT~°~T
.Fj~F (Hofnnann 1979) 7i Y. .~.~-I_N]~P~i. fate f~°)i~llliN'J]u
~i'4~t_M`T~-l-lT]~li~i (Chamberlain and Houang 1984; Pereira
et al 1990: Schonlloltz 1976), 2~E~tT~t · ~r~777l~ili~ (Kagan 1992b) ~
~tV;'~l.lj~'T (Ayliffe 1991; Kagan 1992a; Hitter and Marmion
1987: Schofield 1994; Whyte 1988) ~ Y t §, ~E, hi f tic it ~~ i :,
i~ih~llit~b~li~_~ (Schofield1994). ~—
F?W—7~:tJ;:~7~3t] R~xti, ~;~6t6~6lj-~-~1~;
~ ~ . t ~ ~ ~ 7 ~ ~ ~ ' ~ . 7~ 4/t t ti `) ~4i l—i!; ~i r t ~ t ~ ~ ~i ~: t. ~ ~ ~ r r7
Z~ (Berg l993) . ~it4k°) f l:"r~i)$:ib ~jlJ l ttiJb r ~ :)~i!~Hli :: iF. if t 1_1~ 6. ililt~f t/l
t t~m Hil l-~(i~i7\t `~f :~7.1~-~-~l ~ . 7~ ~> r—~ t_ `~(~`f~i'~4J~.t:-~ ~ ~.
t_, jt.r~ 1-7fl ;~il]7jifl1,r:~J: ~ !~ ;~ (Rutala 1990).
75~r~tl~hil:? t ~1t ~ ~ ·~9 ~ ~ ~ ~ 19$ i:'=itr l~tti-i~- ~ t,
~A;~.~.~t ~¢~;t~ t1. —4>t~1:1t, 11'-~T~il~l7~0~!~_oJ~:~u
iti f rtTI;. ~r.~ Ei b':o) t_~ t-~fl~i :> t t li~ji-;5l:Pj: ~lillit: ~ ~ ~' :~. t: ~ i. Y
~) T.ffl ~i ~ ~ ~ ~ I I I a) ~ `1 ~ ~ ~ ) ~ 1~ ~ ! ~i ~ ~ ~ ~) <, ]- i,Rr ~ I t i ~t i f ~—.TIt l# ~ ~ 1',
|~7~ritl~1t~'t:~t_lt.lilt (AOiN 1982; Bartley 1993). 1tiRZ-J:~<
t3:. fT~q~i::fTta) ~ t~9l_q ~) Z~ _ ~ ~ ~ ~ ~ :~) ~t ~ ;~6 f~m~l~l;
~1~ TfT~q~_~t, rl7l(7)iFti~F7t—)~ ~b~tth t/~ ~/~.
73~4~_ 7 l) :/70~i, ~ ivl'~R,]~bi Elit_~;o 4iR:.~-)t'J:b'. 7$fl-F-
T~q~Ih~_i~t< 2.T,r.t h ~ E ~ 7 i) /7~I0~l ~ (, ~)iZ ~ /1 69'(—
~g~ti J~tq~ O) ~ ~ 7, ~ ~ ~ ~tRJ*3~47i~—4~X,Tt ~ r~f~ ~ ~ (t ~ ~ ~ bi ~ ~
5. Il.~T;f~i.~ L~_ ~ t), I4;:bf~i! t:712~;1~6 q4~7,+7=t t; t-0f~i~l~T~ ktll$q
~O~ (Dardai and lleavner 1987), ~hl t ~ t) talt~:~. ~ 6.
7:fTb97h~ ~ ~ ~|~| t~,7~_ ~ —~ <~/X ~. It ~i~b fr~q~t—
.~_ W~t'b4Y ~ b>~_~('r~=.fi~ h: ~ t . f ~x' - 7 1_ ~ ~
2. ~liR~ill`~9i~:b`~b'~J 'i~nhYbOl-~4~fitiflN3~libiJ> ~ (Beamer
1972; Bradfield et al. 1992; Cunliffe- ieamer 1990; Waynforth 1980'
1987), Ut_bi::, i-s~i~I)~lS;~f,~j~r'~hijl~b>t Wh~.
t-,J`~iijtJJ~!J~. ~bit—4
ah. 3 ~ ~L~YI~q~
~-/~ ~ low 74 ~ ~1~1--~> ( 1}, ~~! At_, an, ~] T~q`-~;
~ ~ ~ low ~ ~ ~ ~ ~ ~ at ~ a' ~ deli,> ~ Il/A ~ ~ ~ ~ a' (Brown 1994; Cunliffe
Beamer 1993). It~Ji~o)5ff,~il:~1 L :, ~~I_,=.;t4Y,1~ ~ h
(~3 (Cunliffe-Beamer 1983, 1993).
,~x ~ *J>~t_~l_~h<·~_~1t, —-I
lb~l~l}, f;Ir f h`~~ ~ twirl_ l. (~ ~ . Latin l'E'P~1
~fi- o.:~4:, JO A:, ~ ~~;h(~
~~+J'$~ml-1~-l
Hat,, ~11~6, i~ti~7it't, ~ .~ it id
~B~
~ 3 ~ ~~
bet, rot t`_~Z'~-5~.
A ~ iN:im) ~ ~ > 1-,J, t¢~!;ffl~rAll; ~ `-~iNq ASHY ~ At_ ,- V`~:tt
Jump) ,~, I ~ God (NRC 1992).
r¢i;j~Aq, IBM hq. F 7 ;~ ~ ~ 1' ff—I_ he ~ :, )~ ~ ~ ~r b9~4z~ ~ hi- ah i
_ Cubist' (NRC 1992; Spinelli 1990).
nabs 1~ A_ J: 7 :_, i~lltriNd ti 1~=~;-ff~ ~ ~ to ~ vow. 'AGE t-~i~ 2; ft
t_~)J~l-)rUt, For mat d>~_l~l7~ (htTE'°~:~t~
{g v), ,- I -, c_a7-' nag lit .t_t~--g~. rh1;~r3tl: ~!~ ,, it
tlt_~-Z~Ct chat_, j$~.ti str'Sq! imps t
1
fL~i~f ~o)^rlT ~ WHO l_~;l:lt :Ti f l
~~L~~f~)~,f ~?~r~ ~ ~ ~7~. v~ ,~ ~ 7Elide~ i.5Tl . .
'Ian,, ,~r~r,rli,lit 1), 7 I r +>r';~,t',l ~ f I'm :.T,r.
`~>lfr<~.r~/jc~-~r,~lT:~I mar- (ALMA 1993).
r~7~,~` fame i ~~,fili~`'f if fly. giJI4)JJ~)ii7~.~R~fIf l V(~l.
g~ 3 ~: rtf ~:f tk~f~t
Bren/.ile. J E 1987 Phyriologic basis and consequences ol dBn-es~ in anh~lals J. AID ~ et Med
/Yssoc 191(10) 1212 1215
Brown M 1 1994 AsepPc curgery hn lodems Pp 67 72 h~ Rndems nad Rndbhs Cunem Rcscaleh
Issues S. M Niemi I S Venable and H. N Guttman eds Belhe~da Md Scienosts Centc~
for Animal Welfare
h Brown. M I and I C Schoheld f994 Perioperative cn~e Pp 79-88 in Ecseminis for Animal
Research: A Primer for Rcsearch Persmmel B T. Bennett M I Brnwn: nnd I C Schofield.
eds Washu~gton D C Natimml Agricoltural Library
Brown M 1. P. T. Pearsm~ tad F. N 'I'm~son 1993 Guidelines tm anknnl surgery u~ research nnd
teaehmg Am 1 Vet Res 54(9) 1544-1559
Butle~ T. M B G Brov\n R C D)sko. E W Fnrd D E HnsEh~s. H J Klth~. J L Le~h~ K A
Morray'D P. Rosenberg J L Smahers and R. B Swenson 1995 Medical management Pp
255 334 in Nonhuman Pru~ntes in Bimnedical Recearch Biology and Managentent B T.
Bem~ett C R Abee and R Hendrickson'eds Snn Diego Cnlif Academic Press
CDC (Centers k~r Disease Cnntrol and Prevention) 1991 Update Nonhu'Dan prknate hDportntion
MMWR Oetober9. 199f
CDC (Cemers for Diseace Contrnl and Prevemion) 1993 Tuberculo~is b~ imported nnnhuman pri-
nnnes-United States Jm~e 1990 May 1993 MMWR loly 30. 1993 Vol 42 no 29
CFR (('ndc of Federnl Regulalions) Title 42 PHS'HHS Subchapter F (Bnportationc) Section 71 53
(Nnnhmnan primates)
Chalfee V W 1974 Surgery nf Inhoratory nnimnis Pp 233 247 in Hnndhonk of Lnborntory Ani-
mal Seieme Vol l E C Meiby Jr nad N. H. Altman eds Cleveland Ohio CRC Press
Chnn~bedah~ G V nnd E llounng 1984 Trial of the use uf ~nosk~ b~ gynecoh~gicnM>perating
theatre Ann R Coil Surg 66(6) 432-433
Cnnlif'te Benmor T. L 1983 Binmethodology nnd surgical technklues Pp 419-420 in The Mnose in
Binmedical Resenrch Vol 111. Nnrmative Bk~logy hDn~unology nml }{n~band~y H L Foste~
J D Smnil nnd J G Fox. eds New Ynrk Acade~nie P'ess
~i Cunliffe-Beamer. T. L 1990 Surgical Techniques Pp 80-85 in Guidelines R>r the Well-Being nf
RodentsinResenrch.f{ N Gutt~nan cd Bethesdn Md ScientistsCenterlorAnimalWelhre
Cunliffe-Benmer T. L f993 Applyb~g principles nf tseptic surgery to rodents AWIC Newsl.
4(2) 3-6
Darda k F. and .l E llenvner 19X7 Respiratm-y nnd en~din~nscular ctfccts of halothnne. isoflurane
' and enflurane delive~ed vin n Jnckson-Rees hreathing sy~tem in rernperaturc contrniled nnd
uncontrniledrnis Meth Find Exp Clin Pharmacol 9(11)717-720
de Snozn M. and A 1. S~nith 1989 G~n~pahsun of Nolath~r~ h~ ccil cultare wilh cun~tmim~al nnd
~nodifed nmuse nmihody prnductinn tests for deteetinn nf nmrine vimses J Clin Micrnbinl
27:185-187.
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