Abbreviations


α

alpha

AChE

acetycholinesterase

AEGL

acute exposure guideline level


β

beta


C

concentration

CNS

central nervous system

Ct

product of concentration and time

CV

conduction velocity

CWA

chemical warfare agent


DAAMS

depot area air monitoring system

DFP

diisopropyl fluorophosphates

DNA

dexyribonucleic acid

DOD

U.S. Department of Defense


EC01

effective concentration estimated to be in 1% of the dosed animals

ECT50

the concentration and time estimated to be that causes an effect in 50% of subjects

ED50

dose estimated to be effective in 50% of the exposed individuals

EEG

electroencephalogram


FDA

Food and Drug Administration


GA

tabun

GB

sarin

GC

gas chromotography



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement



Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.

OCR for page 102
Review of the Department of Defense Research Program on Low-Level Exposures to Chemical Warfare Agents Abbreviations α alpha AChE acetycholinesterase AEGL acute exposure guideline level β beta C concentration CNS central nervous system Ct product of concentration and time CV conduction velocity CWA chemical warfare agent DAAMS depot area air monitoring system DFP diisopropyl fluorophosphates DNA dexyribonucleic acid DOD U.S. Department of Defense EC01 effective concentration estimated to be in 1% of the dosed animals ECT50 the concentration and time estimated to be that causes an effect in 50% of subjects ED50 dose estimated to be effective in 50% of the exposed individuals EEG electroencephalogram FDA Food and Drug Administration GA tabun GB sarin GC gas chromotography

OCR for page 102
Review of the Department of Defense Research Program on Low-Level Exposures to Chemical Warfare Agents GD soman GF cyclosarin GLP good laboratory practice HD sulfur mustard IU/L international units per liter L liter LC50 concentration estimated to be lethal to 50% of subjects LCt50 lethal (estimated to be) concentration-time relationships in 50% of subjects LD50 dose estimated to be lethal to 50% of subjects MAP2 mitogen-activated protein MEGs military exposure guidelines mg milligram mL milliliter MOPP mission-oriented protective posture MRI magnetic resonance imaging mRNA messenger ribonucleic acid MS mass spectroscopy MTD maximum tolerated dose NRC National Research Council ORM operational risk management OP organophosphate PAC presidential advisory committee PBPD physiologically based pharmacodynamic PBPK physiologically based pharmacokinetic PON1 paraxonase 1 REM rapid eye movement RNA ribonucleic acid SFEMG single fiber electromyography t exposure time µg/kg microgram per kilogram µm micrometer µM micromole USACHPPM United States Army Center for Health Promotion and Preventive Medicine WPAFB Wright-Patterson Air Force Base

OCR for page 102
Review of the Department of Defense Research Program on Low-Level Exposures to Chemical Warfare Agents This page intentionally left blank.