proaches exist to help make such decisions, but when the risks to be compared are quite uncertain, or uncertain to different degrees, good [characterization] of uncertainty is necessary in order to arrive at sound solutions [NRC 2000, pp. 60-61].

The need for sound science-based risk assessment data was reinforced by the findings summarized in a recent report (NRC 2004). Best exposure guidance estimates are required for making appropriate course-of-action decisions.

In summary, DOD requires accurate and reliable estimates of the effects of low-level CWA exposures on human performance. DOD states that accurate estimations cannot be derived from the universe of existing data on studies with animals and human research subjects and proposes in this Research Plan a multiyear, multimillion dollar research effort to acquire such information.

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