B
Methods

The committee developed this interim report and arrived at conclusions and recommendations regarding the strengths and weaknesses of the Bioastronautics Roadmap (BR) during a 13-month period from April 2004 to May 2005. During this time, the committee held four data-gathering sessions; made one site visit to the Johnson Space Center in Houston, Texas; and met in closed session seven times to deliberate. Agendas for the open, data-gathering sessions of these meetings are included in this appendix.



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A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA’s Bioastronautics Roadmap B Methods The committee developed this interim report and arrived at conclusions and recommendations regarding the strengths and weaknesses of the Bioastronautics Roadmap (BR) during a 13-month period from April 2004 to May 2005. During this time, the committee held four data-gathering sessions; made one site visit to the Johnson Space Center in Houston, Texas; and met in closed session seven times to deliberate. Agendas for the open, data-gathering sessions of these meetings are included in this appendix.

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A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA’s Bioastronautics Roadmap INSTITUTE OF MEDICINE AGENDA Committee on Aerospace Medicine and Medicine in Extreme Environments and Committee on Review of NASA’s Bioastronautics Critical Path Roadmap Keck Building 500 5th Street, NW Washington, DC Room 110 Monday, April 12, 2004 CLOSED SESSION (committee and staff only) 8:00 a.m.–12:00 p.m. OPEN SESSION 12:00 p.m. Lunch 1:00 p.m. Request for a review of the Bioastronautics Critical Path Roadmap (BCPR) Richard Williams, M.D., Chief Health and Medical Officer, NASA 1:10 p.m. Overview of the Bioastronautics Critical Path Roadmap NASA presenters: Guy Fogleman, director of bioastronautics research, Office of Biological and Physical Research; Howard Ross, acting deputy associate administrator for science, Office of Biological and Physical Research; Marc Shepanek, deputy chief, Medicine of Extreme Environments, NASA; Frank Sulzman, manager, Space Radiation Health Project 1:20 p.m. How the Bioastronautics Critical Path Roadmap captures the critical risks and key research and technology issues for risk reduction, management, and informed decision making

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A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA’s Bioastronautics Roadmap 1:40 p.m. The Bioastronautics Critical Path Roadmap’s method and expression of risk assessment for medical decision making and the BCPR communication of these methods for different mission scenarios 2:20 p.m. Types of risks and impacts of risk as expressed in the Bioastronautics Critical Path Roadmap 3:00 p.m. Break 3:30 p.m. Categories of critical research issues and metrics used in the Bioastronautics Critical Path Roadmap 4:10 p.m. Efficiency and technology issues in the Bioastronautics Critical Path Roadmap 4:50 p.m. Plenary discussion Led by David Longnecker, M.D. 5:30 p.m. Adjourn to reception and dinner with invited guests Location: third floor atrium Tuesday, April 13, 2004 OPEN SESSION 8:00 a.m. Continental breakfast 8:30 a.m. Welcoming remarks David Longnecker, M.D. 8:45 a.m. Overview of related work by the National Academies 9:00 a.m. Space Studies Board/ASEB 9:30 a.m. CAMMEE 10:00 a.m. Break CLOSED SESSION (committee and staff only) 10:15 a.m.–3:30 p.m.

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A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA’s Bioastronautics Roadmap INSTITUTE OF MEDICINE AGENDA Committee on Review of NASA’s Bioastronautics Critical Path Roadmap Keck Building 500 5th Street, NW Washington, DC Room 204 Wednesday, June 9, 2004 OPEN SESSION 9:00 a.m. Welcome and overview of day’s agenda David Longnecker, M.D., and Lisa Vandemark, Ph.D. 9:15 a.m. Briefings related to the review of the Bioastronautics Critical Path Roadmap NASA presenters: Lauren Leveton, Bioastronautics Science Management Team, NASA; Holly Patton, Aerospace Technologist, NASA; David Tomko, Lead Scientist, Biomedical Program, BASA Bioastronautics Research Division; Guy Fogleman, Director of Bioastronautics Research, Office of Biological and Physical Research; Frank Sulzman, Manager, Space Radiation Health Project 12:00 p.m. Lunch 1:00 p.m. Bone loss and countermeasures: historical perspectives and new in-flight clinical studies Jay Shapiro, M.D., Uniformed Services University of the Health Sciences 2:00 p.m. Harmonization of crew living module and extravehicular pressure suit atmospheric constituents and pressures Bruce McCandless, M.S., M.B.A., Lockheed Martin 3:00 p.m. Break 3:30 p.m. An overview of space biology from cells to humans David Klaus, Ph.D., University of Colorado, Boulder 4:30 p.m. Plenary discussion Led by David Longnecker, M.D. 5:30 p.m. Adjourn

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A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA’s Bioastronautics Roadmap Thursday, June 10, 2004 CLOSED SESSION (committee and staff only) 8:30 a.m.–3:00 p.m. INSTITUTE OF MEDICINE AGENDA Committee on Review of NASA’s Bioastronautics Critical Path Roadmap Keck Building 500 5th Street, NW Washington, DC Room 201 Monday, August 2, 2004 OPEN SESSION 9:00 a.m. Welcome, introductions, and overview of day’s agenda David Longnecker, M.D., and Lisa Vandemark, Ph.D. 9:20 a.m. Briefings related to the review of the Bioastronautics Critical Path Roadmap Richard Williams, M.D. 10:30 a.m. Break 11:00 a.m. Briefings related to the review of the Bioastronautics Critical Path Roadmap NASA presenters via videoconference from Johnson Space Center: Guy Fogleman, Director of Bioastronautics Research, Office of Biological and Physical Research; Marc Shepanek, Deputy Chief, Medicine of Extreme Environments, NASA; Desmond Lugg, Chief, Medicine of Extreme Environments, Office of the Chief Medical Officer 11:30 a.m. Question-and-answer discussion David Longnecker, M.D., Moderator 12:00 p.m. Lunch

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A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA’s Bioastronautics Roadmap 1:00 p.m. Advanced life support issues Brian Dunaway, Boeing Corporation CLOSED SESSION (committee and staff only) 2:30 p.m.–5:30 p.m. Tuesday, August 3, 2004 CLOSED SESSION (committee and staff only) 8:30 a.m.–3:00 p.m. INSTITUTE OF MEDICINE AGENDA Committee on Review of NASA’s Bioastronautics Critical Path Roadmap National Academy of Sciences Building 2101 Constitution Avenue, NW Washington, DC Lecture Room Monday, January 31, 2005 OPEN SESSION 9:00 a.m. Welcome and introductions David E. Longnecker, M.D., Chair 9:20 a.m. Overview of the day’s agenda Lisa M. Vandemark, Ph.D., Study Director 9:30 a.m. Guest presentations Admiral Walter Cantrell, NASA Headquarters; Joseph Genovese, Hamilton Sunstrand; Joseph Fuller, Futron Corporation 12:00 p.m. Lunch

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A Risk Reduction Strategy for Human Exploration of Space: A Review of NASA’s Bioastronautics Roadmap 1:00 p.m. Guest presentations Geoffrey McIntyre, Federal Aviation Administration; Michael Gernhardt, NASA Johnson Space Center; Alan Feiveson, NASA Johnson Space Center (via phone conference); William Stone, Stone Aerospace 3:15 p.m. Break 4:00 p.m. Overview of the new Bioastronautics Roadmap Lauren Leveton, Ph.D., NASA Headquarters 4:30 p.m. Plenary discussion Led by David Longnecker, M.D. 5:30 p.m. Adjourn Tuesday, February 1, 2005 CLOSED SESSION (committee and staff only)

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