utility theory, and represent differing research practices and types of trade-offs.

The magnitude of the impacts of regulations for which economic analyses are required is great. The significance of these public interventions argues for careful attention to the development of high-quality, unbiased analyses that include thorough documentation of their limitations. Such analyses must be rigorous and conform to accepted professional standards for best practices. Data, methods, results, uncertainties, and limitations must be clearly communicated.

The rest of this report elaborates on these objectives for regulatory analysis and policy development. Subsequent chapters consider and make recommendations about the use of HALY measures in regulatory CEA, ethical and other nonquantified information to be considered in developing regulatory policies, and the construction and presentation of CEAs using health-related effectiveness measures. Importantly, the conclusions and recommendations presented throughout address the use of CEA specifically for public policy analysis of interventions affecting the environment, public health, and safety. Different characteristics of measures and criteria for use of a particular measure may be of greater relevance in other contexts than the criteria proposed here.

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