TABLE 4-1 Agents and Toxins That Require Registration of the Facility with CDC


Bacillus anthracis

Botulinum neurotoxin producing species of Clostridium

Brucella abortus, Brucella melitensis, Brucella suis

Burkholderia mallei, Burkholderia pseudomallei

Cowdria ruminantium (Heartwater)

Coxiella burnetii

Francisella tularensis

Mycoplasma capricolum/M.F38/M. mucoides capri(contagious caprine pleuropneumonia), Mycoplasma mycoides mycoides (contagious bovine pleuropneumonia)

Rickettsia prowazekii, Rickettsia rickettsii

Yersinia pestis


Coccidioides immitis, Coccidioides posadasii



Botulinum neurotoxins

Clostridium perfringens epsilon toxin





Shigatoxin and Shiga-like ribosome inactivating proteins

Staphlococcal enterotoxins


T-2 toxin


Bovine spongiform encephalopathy agent


African horse sickness virus

African swine fever virus

Akabane virus

Avian influenza virus (highly pathogenic)

Bluetongue virus (exotic)

Camel pox virus

Cercopithecine herpesvirus 1 (Herpes B virus)

Classical swine fever virus

Crimean-Congo haemorrhagic fever virus

Eastern Equine encephalitis virus

Ebola virus

Foot-and-mouth disease virus

Goat pox virus

Hendra virus

Influenza virus (reconstructed replication competent forms of the 1918 pandemic influenza virus containing any portion of the coding regions of all eight gene segments)

Japanese encephalitis virus

Lassa virus

Lumpy skin disease virus

Malignant catarrhal fever virus (Alcelaphine herpesvirus type 1)

Marburg virus

Menangle virus

Monkeypox virus

Newcastle disease virus (velogenic)

Nipah virus

Peste des petits ruminants virus

Rift Valley fever virus

Rinderpest virus

Sheep pox virus

South American haemorrhagic fever viruses (Junin, Machupo, Sabia, Flexal, Guanarito)

Swine vesicular disease virus

Tick-borne encephalitis (flavi) viruses (Central European tick-born encephalitis, Far Eastern tick-borne encephalitis [Russian spring and summer encephalitis], Kyasanur Forest disease, Omsk hemorrhagic fever)

Variola major virus (Smallpox virus)

Variola minor virus (Alastrim)

Venezuelan equine encephalitis virus

Vesicular stomatis viruses (exotic)

The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement