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survey health status in the Medical Outcomes Study. It is a measure of health status designed for use in clinical practice, research, health policy evaluations, and general population surveys. It includes eight scales that assess the following general health concepts: physical functioning, role limitations due to physical health problems (role physical), bodily pain, general health perceptions, vitality, social functioning, role limitations due to emotional problems (role emotional), and mental health.

MSIS-29:29-item Multiple Sclerosis Impact Scale

MSIS-29 can be used to measure therapeutic outcomes in persons with multiple sclerosis. It consists of 29 items: (1) 3 items dealing with limited abilities and (2) 26 items related to the symptoms or the consequences of the illness.

MSWS-12:12-item Multiple Sclerosis Walking Scale

MSWS-12 is a questionnaire that asks the patient to self-rate the degree of limitation in walking due to multiple sclerosis experienced in the prior 2 weeks for each of 12 activities.

POMS: Profile of Mood States

The POMS provides a method to assess transient, fluctuating mood states. The key areas measured are tension-anxiety, anger-hostility, fatigue-inertia, depression-dejection, vigor-activity, and confusion-bewilderment.

SIP: Sickness Impact Profile

SIP describes relative functional limitations across 12 specific areas: ambulation, body care and movement, mobility, emotional behavior, social interaction, alertness behavior, communication, work, sleep and rest, eating, home management, and recreation and pastimes.

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