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Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem
F
National Institutes of Health Sleep-Related Initiatives: 1994–2004
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Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem
TABLE F-1 Sleep Initiatives (RFAs) Sponsored by the National Institutes of Health, 1994–2004
Title
Primary Purpose
Participating Institutes/Centers
Funding Activity
Year
SCOR in Neurobiology of Sleep & Sleep Apnea: RFA-HL-96-014
Establish specialized centers of research (SCORs) programs to foster translational research.
NHLBI
P50
1996
Molecular Biology and Genetics of Sleep and Sleep Disorders: RFA-HL-96-015
Advance the understanding of the molecular and genetic basis of sleep and sleep disorders.
NHLBI, NIMH, NICHD
R01
1996
Sleep Academic Award: HL-97-015; HL-96-021
Develop and/or improve the quality of medical curricula for the prevention, management, and control of sleep disorders.
NHLBI
K07
1996, 1997
Obstructive Sleep Apnea in Children: HL-98-004
Define abnormalities in airway structure and function responsible for obstructive sleep apnea in children, and identify physiological and clinical measures associated with increased morbidity.
NHLBI, NIDR, NICHD
R01
1997
Phenotypic Characterization of Sleep in Mice: RFA-HL-99-001
Develop improved molecular, cellular, and systems approaches to investigate sleep and circadian phenotypes in mice.
NHLBI, NIMH, NIA, NINDS
R01
1998
Nocturnal Asthma, Chronobiology, and Sleep: RFA-HL-99-011
Establish the mechanisms that underlie the chronobiology of nocturnal exacerbations of asthma and airway inflammation, as well as the role played by sleep and sleep disturbances.
NHLBI
R01
1999
Implementation of the National Occupational Research Agenda: RFA-OH-99-002
Develop knowledge that can be used in preventing occupational diseases and injuries and to better understand their underlying pathophysiology.
NIOSH, NCI, NHLBI, NIA, NIDCD, NIEHS
R01, R18
1999
Data Coordinating Center for Sleep Heart Health Study: RFA-HL-99-014
Establish a new data coordinating center for the Sleep Heart Health Study.
NHLBI
U01
1999
Research on Alcohol and Sleep: RFA-AA-00-005
Stimulate research on alcohol and sleep in areas that may improve understanding of the etiology and treatment of alcoholism.
NIAAA
R01, R21
2000
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Sleep Disorders and Sleep Deprivation: An Unmet Public Health Problem
Oxygen Sensing During Intermittent Hypoxia: RFA-HL-00-004
Improve understanding of how intermittent hypoxia contributes to the pathophysiology of cardiopulmonary, vascular, hematological, and sleep disorders.
NHLBI
R01
2000
Ancillary Studies in Conjunction with SHOW Trial: RFA-DK-00-017
Develop basic, clinical, and behavioral ancillary research studies of the Study of Health Outcomes of Weight-Loss (SHOW) clinical trial.
NIDDK, NHLBI, NINR, NIAMS, NIDCR
R01
2000
Interrelationships Between Sleep and Heart, Lung, and Blood Diseases: RFA-HL-01-009
Elucidate characteristics of sleep physiology, sleep disorders, and pathophysiological mechanisms mediating the interrelationship between sleep disturbance and heart, lung, and blood diseases.
NHLBI, NIDA
R01
2001
Sleep and Sleep Disorders in Children: RFA-HL-01-006
Improve the understanding of fundamental biological mechanisms through which sleep deprivation and sleep disorders affect the cardiopulmonary, hematological, immunological, mental, and behavioral health of children.
NHLBI, NIMH, NINR, NICHD
R01
2001
Role of Sleep and Sleep Disordered Breathing in the Metabolic Syndrome: RFA-HL-03-008
Elucidate the relationship of sleep deprivation and sleep-disordered breathing to characteristics of the metabolic syndrome including obesity, high blood pressure, dyslipidemia, insulin resistance, and vascular inflammation.
NHLBI, NIA
R01
2002
Inter-relationships of Sleep, Fatigue, and HIV/AIDS: RFA-HL-04-010
Elucidate the etiology of sleep disturbances and fatigue associated with human immunodeficiency virus infection and acquired immunodeficiency disease syndrome.
NHLBI, NIMH
R01
2003
NOTE: Primary purpose of each PA and RFA are adapted from language in NIH announcements. NCCAM = National Center for Complementary and Alternative Medicine; NCI = National Cancer Institute; NCSDR = National Center on Sleep Disorders Research; NHLBI = National Heart, Lung, and Blood Institute; NIA = National Institute on Aging; NIAAA = National Institute on Alcohol Abuse and Alcoholism; NIAID = National Institute of Allergy and Infectious Diseases; NIAMS = National Institute of Arthritis and Musculoskeletal and Skin Diseases; NICHD = National Institute of Child Health and Human Development; NIDA = National Institute on Drug Abuse; NIDCD = National Institute on Deafness and Other Communication Disorders; NIDCR = National Institute of Dental and Craniofacial Research; NIDDK = National Institute of Diabetes and Digestive and Kidney Diseases; NIDR = National Institute of Dental Research; NIEHS = National Institute of Environmental Health Sciences; ; NIH= National Institutes of Health; NIMH = National Institute of Mental Health; NINDS = National Institute of Neurological Disorders and Stroke; NINR = National Institute of Nursing Research; NIOSH = National Institute for Occupational Safety and Health; PA = program announcement; RFA = request for application.
SOURCE: National Heart, Lung, and Blood Institute, 2003; National Sleep Disorders Research Plan, 2003 Bethesda, MD: NIH.
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TABLE F-2 Sleep Initiatives (PAs) Sponsored by the National Institutes of Health, 1994–2004
Title
Primary Purpose
Participating Institutes/Centers
Funding Activity
Year
Basic and Clinical Research Sleep & Wakefulness: PA-95-014
Enhance sleep research in the following areas: neuroscienceon and behavioral science; molecular and cellular mechanisms of sleep and circadian rhythms across the life span; development of sleep from fetal life through infancy; role of dreaming in humans; etiological factors and pathophysiology of transient or persistent insomnia; and the treatment of sleep disorders.
NIA, NIAAA, NICHD, NIDA, NHLBI, NIMH, NINDS, NINR
R01, R03, R29, P01
1994
Innovative Approaches to Developing New Technologies: PA-97-014
Support research to identify, create, and develop innovative technologies and to provide these technologies for biomedical research.
NCRR
R21
1996
Research on Musculoskeletal Fitness and Sports Medicine: PA-97-025
Study a broad range of basic and clinical topics related to musculoskeletal fitness, exercise physiology, and sports medicine.
NIAMS, NICHD, NINR
R01, R03, R29, K01, K02, K08, P01
1997
Institutional National Research Service Award in Sleep Research: PA-97-064
Ensure that scientists, highly trained in sleep research, are available in adequate numbers to address important gaps in our biomedical and biological understanding of sleep, including those outlined in the NIH director’s Sleep Disorders Research Plan.
NHLBI, NIA, NIAAA, NICHD, NIDA, NIMH, NINDS, NINR
T32
1997
Bioengineering Research Grants: PAR-99-009
Support basic bioengineering research whose outcomes are likely to advance health or health-related research within the mission of the NIH.
NCI, NCRR, NEI, NHGRI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NICHD, NIDA, NIDCD, NIMH, NINDS, NINR, NLM
R01
1998
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Human Brain Project (Neuroinformatics): PAR-99-138
Encourage and support investigator-initiated, neuroinformatics research that will lead to new digital and electronic tools for all domains of neuroscience research.
NIMH, NIDA, NSF, NIA, NICHD, NIDCD, NLM, NASA, FIC, DOE, NIAAA, NHLBI, NIDCR, NCI, NINDS
R01, P01, P20
1999
Occupational Safety and Health Research: PA-99-143
Develop knowledge that can be used in preventing occupational diseases and injuries, and better understand their underlying pathophysiology.
NIOSH, NCI, NHLBI, NIA, NIAAA, NIAID, NIAMS, NIDCD, NIEHS
R01
1999
Restless Legs Syndrome and Periodic Limb Movement Disorder: PA-01-086
Develop an understanding of the pathogenesis of RLS and PLMD that will lead to new forms of treatment.
NINDS, NHLBI, NIA, NIMH
R01
2001
Research on Sleep and Sleep Disorders: PA-05-046
Advance biomedical knowledge related to sleep or sleep disorders; improve understanding of the neurobiology or functions of sleep over the life span; enhance timely diagnosis and effective treatment for individuals affected by sleep-related disorders; or implement and evaluate innovative community-based public health education and intervention programs.
NHLBI, NCSDR, NIA, NIAAA, NIAMS, NCI, NICHD, NCCAM, NIDA, NIMH, NINDS, NINR, ORWH
R01, R21
2004
NOTE: Primary purpose of each PA and RFA are adapted from language in NIH announcements. DOE = Department of Energy; FIC = Fogarty International Center; NASA = National Aeronautics and Space Administration; NCCAM = National Center for Complementary and Alternative Medicine; NCI = National Cancer Institute; NCRR = National Center for Research Resources; NCSDR = National Center on Sleep Disorders Research; NEI = National Eye Institute; NHGRI = National Human Genome Research Institute; NHLBI = National Heart, Lung, and Blood Institute; NIA = National Institute on Aging; NIAAA = National Institute on Alcohol Abuse and Alcoholism; NIAID = National Institute of Allergy and Infectious Diseases; NIAMS = National Institute of Arthritis and Musculoskeletal and Skin Diseases; NICHD = National Institute of Child Health and Human Development; NIDA = National Institute on Drug Abuse; NIDCD = National Institute on Deafness and Other Communication Disorders; NIDCR = National Institute of Dental and Craniofacial Research; NIEHS = National Institute for Environmental Health Sciences; NIH= National Institutes of Health; NIMH = National Institute of Mental Health; NINDS = National Institute of Neurological Disorders and Stroke; NINR = National Institute of Nursing Research; NIOSH = National Institute for Occupational Safety and Health; NLM = National Library of Medicine; NSF= National Sleep Foundation; ORWH = Office of Research on Women’s Health; PA = program announcement; RFA = request for application.
SOURCES: National Heart Lung and Blood Institute, 2003; National Sleep Disorders Research Plan, 2003.Bethesda, MD: NIH.
Representative terms from entire chapter:
sleep medicine
