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Preterm Birth: Causes, Consequences, and Prevention (2007)
Board on Health Sciences Policy (HSP)

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. "5 Medical and Pregnancy Conditions Associated with Preterm Birth ." Preterm Birth: Causes, Consequences, and Prevention. Washington, DC: The National Academies Press, 2007.

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Preterm Birth: Causes, Consequences, and Prevention

nancy rates did not differ. Twin pregnancies were reduced from 19 percent to 3 percent (Gordts et al., 2005).

Stricter guidelines on the number of embryos transferred should be emphasized by a number of U.S. professional organizations and not just ASRM. Similar best-practice guidelines should be outlined for other infertility treatments that use ARTs, such as ovulation induction. Such guidelines should recommend the use of strict ultrasound guidance and abandonment of a cycle if too many follicles develop. Policy makers should mandate the more systematic collection of data on such procedures and should also consider recommending the use of medication to stimulate egg production. Professional organizations and surveillance activities should redefine success as singleton live births (rather than pregnancy rates). Efforts to reeducate ART consumers on the risks of multiple gestation and preterm birth must transpire simultaneously. Other policies regarding access to assisted reproduction should also be further explored.

Access to reproductive health care and reproductive technology may be a double-edged sword when it comes to ARTs. States with legally mandated coverage for infertility treatment, including ARTs, were the states with the highest rates of ART procedures per million population (Massachusetts, New Jersey, Maryland, the District of Columbia, and Rhode Island) (CDC, 2002b). In Massachusetts, a rise in the state’s rate of multiple births can be directly linked to mandated insurance coverage of infertility services (CDC, 1999a). Sweden and Belgium exemplify a contrasting approach, with public funding limited to the coverage of only SET cycles, thus freeing infertile couples from the financial pressure to transfer as many embryos as possible.

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168
Front Matter (R1-R18)
Summary (1-30)
1 Introduction (31-52)
SECTION I Measurement : 2 Measurement of Fetal and Infant Maturity (53-83)
Section I Recommendations (84-86)
SECTION II Causes of Preterm Birth: 3 Behavioral and Psychosocial Contributors to Preterm Birth (87-123)
4 Sociodemographic and Community Factors Contributing to Preterm Birth (124-147)
5 Medical and Pregnancy Conditions Associated with Preterm Birth (148-168)
6 Biological Pathways Leading to Preterm Birth (169-206)
7 Role of Gene-Environment Interactions in Preterm Birth (207-228)
8 Role of Environmental Toxicants in Preterm Birth (229-254)
Section II Recommendations (255-258)
SECTION III Diagnosis and Treatment of Preterm Labor: 9 Diagnosis and Treatment of Conditions Leading to Spontaneous Preterm Birth (259-307)
Section III Recommendations (308-310)
SECTION IV Consequences of Preterm Birth: 10 Mortality and Acute Complications in Preterm Infants (311-345)
11 Neurodevelopmental, Health, and Family Outcomes for Infants Born Preterm (346-397)
12 Societal Costs of Preterm Birth (398-429)
Section IV Recommendations (430-432)
SECTION V Research and Policy: 13 Barriers to Clinical Research on Preterm Birth and Outcomes of Preterm Infants (433-454)
14 Public Policies Affected by Preterm Birth (455-472)
Section V Recommendations (473-476)
15 A Research Agenda to Investigate Preterm Birth (477-492)
References (493-590)
Appendix A Data Sources and Methods (591-603)
Appendix B Prematurity at Birth: Determinents, Consequences, and Geographic Variation (604-643)
Appendix C A Review of Ethical Issues involved in Premature Birth (644-687)
Appendix D A Systematic Review of Costs Associated with Preterm Birth (688-724)
Appendix E Selected Programs Funding Preterm Birth Research (725-731)
Appendix F Committee and Staff Biographies (732-740)
Index (741-772)