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Preterm Birth: Causes, Consequences, and Prevention (2007)
Board on Health Sciences Policy (HSP)

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. "11 Neurodevelopmental, Health, and Family Outcomes for Infants Born Preterm ." Preterm Birth: Causes, Consequences, and Prevention. Washington, DC: The National Academies Press, 2007.

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Preterm Birth: Causes, Consequences, and Prevention

Number of Subjects

Gestational Age (wk)

Birth Weight (g)

Percentage of Subjects with Scores:

2 SDs below the Mean

1–2 SDs below the Mean

Normal

136

 

<1,000

10

16

74

60

<750

37

 

 

43

 

750–1,499

15

 

 

41

 

>2,500

6

 

 

40

 

<750

22.5

25

52.5

110

 

750–1000

12

12

76

124

 

Fullterm

0

8

92

motor integration, memory for location, sustained attention, and vocabulary, as compared to a matched control group of children born at term (Caravale et al., 2005).

A number of studies have demonstrated that preterm children who were born with birth weights less than 1,000 or 1,500 grams and who had normal IQ scores have more problems with attention, executive function (i.e., organization and planning skills), memory, language, learning disabilities, spatial skills, and fine and gross motor function than controls who were born with normal birth weights (Anderson and Doyle, 2003; Aylwarda, 2002a; Goyen et al., 1998; Grunau et al., 2005; Hack and Taylor, 2000; Halsey et al., 1993; Mikkola et al., 2005; O’Callaghan et al., 1996; Ornstein et al., 1991; Rose et al., 2005; Saigal et al., 1991).

School Problems

Difficulty with cognitive processes contributes to the increased risk of school problems seen in children born preterm (Aylward, 2002a; Grunau et al., 2002). In a study of 153 children born at less than 28 weeks of gestation, only half were ready and able to enter kindergarten with their peers (Msall et al., 1992). Speech and language delays, attention deficits, and learning disabilities were common. Among 8- to 10-year-old children who were born preterm with birth weights of less than 800 or 1,000 grams, 13 to 33 percent repeated a grade, 15 to 47 percent required some special education support, and 2 to 20 percent were in special education placements (Buck et al., 2000; Gross et al., 2001; Whitfield et al., 1997).

Page
363
Front Matter (R1-R18)
Summary (1-30)
1 Introduction (31-52)
SECTION I Measurement : 2 Measurement of Fetal and Infant Maturity (53-83)
Section I Recommendations (84-86)
SECTION II Causes of Preterm Birth: 3 Behavioral and Psychosocial Contributors to Preterm Birth (87-123)
4 Sociodemographic and Community Factors Contributing to Preterm Birth (124-147)
5 Medical and Pregnancy Conditions Associated with Preterm Birth (148-168)
6 Biological Pathways Leading to Preterm Birth (169-206)
7 Role of Gene-Environment Interactions in Preterm Birth (207-228)
8 Role of Environmental Toxicants in Preterm Birth (229-254)
Section II Recommendations (255-258)
SECTION III Diagnosis and Treatment of Preterm Labor: 9 Diagnosis and Treatment of Conditions Leading to Spontaneous Preterm Birth (259-307)
Section III Recommendations (308-310)
SECTION IV Consequences of Preterm Birth: 10 Mortality and Acute Complications in Preterm Infants (311-345)
11 Neurodevelopmental, Health, and Family Outcomes for Infants Born Preterm (346-397)
12 Societal Costs of Preterm Birth (398-429)
Section IV Recommendations (430-432)
SECTION V Research and Policy: 13 Barriers to Clinical Research on Preterm Birth and Outcomes of Preterm Infants (433-454)
14 Public Policies Affected by Preterm Birth (455-472)
Section V Recommendations (473-476)
15 A Research Agenda to Investigate Preterm Birth (477-492)
References (493-590)
Appendix A Data Sources and Methods (591-603)
Appendix B Prematurity at Birth: Determinents, Consequences, and Geographic Variation (604-643)
Appendix C A Review of Ethical Issues involved in Premature Birth (644-687)
Appendix D A Systematic Review of Costs Associated with Preterm Birth (688-724)
Appendix E Selected Programs Funding Preterm Birth Research (725-731)
Appendix F Committee and Staff Biographies (732-740)
Index (741-772)