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Preterm Birth: Causes, Consequences, and Prevention (2007)
Board on Health Sciences Policy (HSP)

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. "SECTION V Research and Policy: 13 Barriers to Clinical Research on Preterm Birth and Outcomes of Preterm Infants ." Preterm Birth: Causes, Consequences, and Prevention. Washington, DC: The National Academies Press, 2007.

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Preterm Birth: Causes, Consequences, and Prevention

and infants born preterm or with low birth weights and their sequelae include the following:

  • Administration for Children and Families

  • Agency for Healthcare Research and Quality

    • Centers for Disease Control and Prevention

    • National Center for Birth Defects and Developmental Disabilities

    • National Center for Chronic Disease Prevention and Health Promotion

  • National Center for Health Statistics

  • Centers for Medicare and Medicaid Services

  • Food and Drug Administration

  • Health Resources and Services Administration

    • Bureau of Primary Health Care

    • Maternal and Child Health Bureau

  • Indian Health Service

  • National Institutes of Health

    • National Center for Complementary and Alternative Medicine

    • National Center on Minority Health and Health Disparities

    • National Heart, Lung, and Blood Institute

    • National Institute on Alcohol Abuse and Alcoholism

    • National Institute of Allergy and Infectious Disease

    • National Institute of Child Health and Human Development

    • National Institute on Deafness and Other Communication Disorders

    • National Institute of Dental and Craniofacial Research

    • National Institute of Diabetes and Digestive and Kidney Diseases

    • National Institute on Drug Abuse

    • National Institute of Environmental Health Sciences

    • National Institute of Mental Health

    • National Institute of Nursing Research

  • Substance Abuse and Mental Health Services Administration

ETHICAL AND LIABILITY ISSUES IN REPRODUCTION RESEARCH

Many ethical issues involved in reproduction research are being discussed and debated at this time, and some may be obstacles to this research. One issue involves whether there is a benefit to the mother and her fetus of inclusion in reproduction research and whether those who are enrolled in research are better off than those who are not. Another challenge involves the documented prevalence of off-label medication use and the professional obligation to study off-label medication use. For neonates, there has been a

Page
447
Front Matter (R1-R18)
Summary (1-30)
1 Introduction (31-52)
SECTION I Measurement : 2 Measurement of Fetal and Infant Maturity (53-83)
Section I Recommendations (84-86)
SECTION II Causes of Preterm Birth: 3 Behavioral and Psychosocial Contributors to Preterm Birth (87-123)
4 Sociodemographic and Community Factors Contributing to Preterm Birth (124-147)
5 Medical and Pregnancy Conditions Associated with Preterm Birth (148-168)
6 Biological Pathways Leading to Preterm Birth (169-206)
7 Role of Gene-Environment Interactions in Preterm Birth (207-228)
8 Role of Environmental Toxicants in Preterm Birth (229-254)
Section II Recommendations (255-258)
SECTION III Diagnosis and Treatment of Preterm Labor: 9 Diagnosis and Treatment of Conditions Leading to Spontaneous Preterm Birth (259-307)
Section III Recommendations (308-310)
SECTION IV Consequences of Preterm Birth: 10 Mortality and Acute Complications in Preterm Infants (311-345)
11 Neurodevelopmental, Health, and Family Outcomes for Infants Born Preterm (346-397)
12 Societal Costs of Preterm Birth (398-429)
Section IV Recommendations (430-432)
SECTION V Research and Policy: 13 Barriers to Clinical Research on Preterm Birth and Outcomes of Preterm Infants (433-454)
14 Public Policies Affected by Preterm Birth (455-472)
Section V Recommendations (473-476)
15 A Research Agenda to Investigate Preterm Birth (477-492)
References (493-590)
Appendix A Data Sources and Methods (591-603)
Appendix B Prematurity at Birth: Determinents, Consequences, and Geographic Variation (604-643)
Appendix C A Review of Ethical Issues involved in Premature Birth (644-687)
Appendix D A Systematic Review of Costs Associated with Preterm Birth (688-724)
Appendix E Selected Programs Funding Preterm Birth Research (725-731)
Appendix F Committee and Staff Biographies (732-740)
Index (741-772)