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Preterm Birth: Causes, Consequences, and Prevention (2007)
Board on Health Sciences Policy (HSP)

Page
473
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Preterm Birth: Causes, Consequences, and Prevention

Section V
Research and Policy

RECOMMENDATIONS

Recommendation V-1: The National Institutes of Health and private foundations should establish integrated multidisciplinary research centers. The objective of these centers will be to focus on understanding the causes of preterm birth and the health outcomes for women and their infants who were born preterm.


Consistent with the Roadmap initiative of the National Institutes of Health, these activities should include the following:

  • Basic, translational, and clinical research involving the clinical, basic, and behavioral and social science disciplines is needed. This research should include but not be limited to investigations covered by recommendations pertaining to the etiologies of preterm birth; the psychosocial, behavioral, sociodemographic, and environmental toxicant exposure-related risk factors associated with preterm birth; the disparities in the rates of preterm birth by race and ethnicity; the identification and treatment of women at risk of preterm labor; quality of health care provided to infants born preterm; and health services research.

  • Sustained intellectual leadership of these research activities is essential to make progress in understanding and improving the outcomes for women and their infants who have been born preterm.

Page
473
Front Matter (R1-R18)
Summary (1-30)
1 Introduction (31-52)
SECTION I Measurement : 2 Measurement of Fetal and Infant Maturity (53-83)
Section I Recommendations (84-86)
SECTION II Causes of Preterm Birth: 3 Behavioral and Psychosocial Contributors to Preterm Birth (87-123)
4 Sociodemographic and Community Factors Contributing to Preterm Birth (124-147)
5 Medical and Pregnancy Conditions Associated with Preterm Birth (148-168)
6 Biological Pathways Leading to Preterm Birth (169-206)
7 Role of Gene-Environment Interactions in Preterm Birth (207-228)
8 Role of Environmental Toxicants in Preterm Birth (229-254)
Section II Recommendations (255-258)
SECTION III Diagnosis and Treatment of Preterm Labor: 9 Diagnosis and Treatment of Conditions Leading to Spontaneous Preterm Birth (259-307)
Section III Recommendations (308-310)
SECTION IV Consequences of Preterm Birth: 10 Mortality and Acute Complications in Preterm Infants (311-345)
11 Neurodevelopmental, Health, and Family Outcomes for Infants Born Preterm (346-397)
12 Societal Costs of Preterm Birth (398-429)
Section IV Recommendations (430-432)
SECTION V Research and Policy: 13 Barriers to Clinical Research on Preterm Birth and Outcomes of Preterm Infants (433-454)
14 Public Policies Affected by Preterm Birth (455-472)
Section V Recommendations (473-476)
15 A Research Agenda to Investigate Preterm Birth (477-492)
References (493-590)
Appendix A Data Sources and Methods (591-603)
Appendix B Prematurity at Birth: Determinents, Consequences, and Geographic Variation (604-643)
Appendix C A Review of Ethical Issues involved in Premature Birth (644-687)
Appendix D A Systematic Review of Costs Associated with Preterm Birth (688-724)
Appendix E Selected Programs Funding Preterm Birth Research (725-731)
Appendix F Committee and Staff Biographies (732-740)
Index (741-772)

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OCR for page 473
Preterm Birth: Causes, Consequences, and Prevention Section V Research and Policy RECOMMENDATIONS Recommendation V-1: The National Institutes of Health and private foundations should establish integrated multidisciplinary research centers. The objective of these centers will be to focus on understanding the causes of preterm birth and the health outcomes for women and their infants who were born preterm. Consistent with the Roadmap initiative of the National Institutes of Health, these activities should include the following: Basic, translational, and clinical research involving the clinical, basic, and behavioral and social science disciplines is needed. This research should include but not be limited to investigations covered by recommendations pertaining to the etiologies of preterm birth; the psychosocial, behavioral, sociodemographic, and environmental toxicant exposure-related risk factors associated with preterm birth; the disparities in the rates of preterm birth by race and ethnicity; the identification and treatment of women at risk of preterm labor; quality of health care provided to infants born preterm; and health services research. Sustained intellectual leadership of these research activities is essential to make progress in understanding and improving the outcomes for women and their infants who have been born preterm.

OCR for page 474
Preterm Birth: Causes, Consequences, and Prevention Mentored research training programs should be integral parts of these centers. Fostering the development of basic and clinical researchers, including facilitating opportunities for funding and promotion, is critical. Funding agencies should provide ample and sustained funds to allow these centers to investigate the complex syndrome of preterm birth, analogous to programs developed to study cancer and cardiovascular disease. Recommendation V-2: Establish a quality agenda. Investigators, professional societies, state agencies, payors, and funding agencies should establish a quality agenda with the intent of maximizing outcomes with current technology for infants born preterm. This agenda should define quality across the full spectrum of providers who treat women delivering preterm and infants born preterm; identify efficacious interventions for preterm infants and identify the quality improvement efforts that are needed to incorporate these interventions into practice; and analyze variations in outcomes for preterm infants among institutions. Recommendation V-3: Conduct research to understand the impact of the health care delivery system on preterm birth. The National Institutes of Health, the Agency for Healthcare Quality and Research, and private foundations should conduct and support research to understand the consequences of the organization and financing of the health care delivery system on access, quality, cost, and the outcomes of care as they relate to preterm birth throughout the full reproductive and childhood spectrum. Recommendation V-4: Study the effects of public programs and policies on preterm birth. The National Institutes of Health, the Centers for Medicare and Medicaid Services, and private foundations should conduct and/or support research on the role of social programs and policies on the occurrence of preterm birth and the health of children born preterm. Recommendation V-5: Conduct research that will inform public policy. In order to formulate effective public policies to reduce preterm birth and assure healthy outcomes for infants, public and private funding agencies and organizations, state agencies, payors, professional societies, and researchers will need to work to imple-

OCR for page 475
Preterm Birth: Causes, Consequences, and Prevention ment all of the previous recommendations. Research in the areas of better defining the problem of preterm birth, clinical investigations, and etiologic and epidemiologic investigations is critical to conduct before policy makers can create policies that will successfully address this problem.

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Representative terms from entire chapter:

preterm delivery