Robert M. Califf, M.D., is associate vice chancellor for clinical research; director of the Duke Clinical Research Institute (DCRI); and professor of medicine, Division of Cardiology, at the Duke University Medical Center, Durham, North Carolina. He has served as an editor of landmark textbooks on cardiovascular medicine and has been an author or coauthor of more than 650 peer-reviewed journal articles. Dr. Califf has led the DCRI efforts for many of the best-known clinical trials in cardiovascular disease. He is considered an international leader in the fields of health outcomes, quality of care, and medical economics. Additionally, he has served on the Cardiorenal Advisory Panel of the U.S. Food and Drug Administration (FDA) and the Pharmaceutical Roundtable of the IOM. He also served on the IOM committee that recommended Medicare coverage of clinical trials, and he is director of the coordinating center for the Centers for Education & Research on Therapeutics (CERTs), a public–private partnership among the Agency for Healthcare Research and Quality, the FDA, academia, the medical products industry, and consumer groups. This partnership focuses on research and education that will advance the best use of medical products. Dr. Califf graduated from Duke University in 1973 and from Duke University Medical School in 1978. He performed his internship and residency at the University of California at San Francisco and his fellowship in Cardiology at Duke University. He is board-certified in internal medicine (1984) and cardiology (1986) and is a fellow of the American College of Cardiology (1988).

H. Eric Cannon, Pharm.D., is director of pharmacy services and health and wellness at IHC Health Plans, a division of Intermountain Health Care in Salt Lake City, Utah. IHC is an integrated health care system with 20 hospitals, 68 physician clinics and surgery centers, and more than 450 employed community-based physicians. Dr. Cannon has worked in pharmacy for the past 15 years. He received his doctor of pharmacy degree from Idaho State University. He has pharmacy experience in the hospital, retail, long-term care, and home health areas. Dr. Cannon is a member of the Academy of Managed Care Pharmacy and currently serves on the legislative committee, which he will chair in the coming year. At IHC Health Plans, he works to develop, implement, and administer programs to control the cost and utilization of pharmaceuticals within the IHC system. He makes frequent presentations to employers, brokers, and health care providers on pharmaceutical trends and pharmaceutical management techniques. Dr. Cannon has responsibility for the management and administration of pharmaceuticals used by IHC’s members. As cochair of IHC’s Corporate Pharmacy and Therapeutics Committee, he helps promote physician/pharmacy education and interaction programs, as well as formulary

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