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adapted from a Burroughs Wellcome Fund survey (Pion and Ionescu-Pioggia, 2003). The vast majority of grantees believed that receiving a CSDA grant influenced their clinical research careers.

7. Commitment to Clinical Research Career. When asked if they plan to spend the majority of their career conducting clinical research, 100 percent of the grantee respondents answered yes. This ensures that the goal of the program—to foster the development of physician-scientists—is on target.


The first Clinical Scientist Award Program grant recipients received their awards only seven years ago, and the most recent recipients began their fourth year of the grant cycle in July 2005. The lack of sufficient elapsed time since making these grants and the relatively small number of CSDA grantees (only 71) argue against attempting to conduct a rigorous evaluation of the program at this time. Nevertheless, information garnered from annual grantee progress reports, a year 3 renewal review of faculty-level grantees, transition reviews of fellow-level grantees to the faculty level, and a January 2005 survey of grantees has been used to monitor the progress of the CSDA grantees and to determine if the program is on track to meet its goals. This information indicates that, with few exceptions, CSDA grantees have made significant progress toward establishing themselves as productive clinical investigators. The CSDA program appears to be accomplishing its goal of fostering the development of future clinical research leaders. Based on these findings, the Doris Duke Charitable Foundation reinstated the program, and awards were announced in the fall of 2005. The foundation will continue to collect data on its CSDA grantees and, when appropriate, hopes to collaborate with other foundations and philanthropies to do comparative studies.


Nathan, D. G. 1998. Clinical research: Perceptions, reality, and proposed solutions. National Institutes of Health Directors Panel on Clinical Research. JAMA 280:1427.

Nathan, D. G. 2002. Careers in translational clinical research-historical perspectives, future challenges. JAMA 287:832.

Pion, G., and M. Ionescu-Pioggia. 2003. Bridging postdoctoral training and a faculty position: Initial outcomes of the Burroughs Wellcome Fund career awards in the biomedical sciences. Academic Medicine 78:177–186.

Zemlo, T., H. H. Garrison, N. C. Partridge, and T. J. Levy. 2000. The physician-scientist: Career issues and challenges at the year 2000. FASEB Journal 14:221–230.

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