Vaughn, D. 2006 (January 23). Military Infectious Diseases Reseach Program. Paper presented at the Institute of Medicine Workshop on Military Malaria Vaccine Development, Silver Spring, Maryland. Institute of Medicine Committee on DoD Malaria Vaccine Research—A Program Review.

Wang R, Doolan DL, Le TP, Hedstrom RC, Coonan KM, Charoenvit Y, Jones TR, Hobart P, Margalith M, Ng J, Weiss WR, Sedegah M, de Taisne C, Norman JA, Hoffman SL. 1998. Induction of antigen-specific cytotoxic T lymphocytes in humans by a malaria DNA vaccine. Science 282(5388):476–480.

Wang R, Epstein J, Charoenvit Y, Baraceros FM, Rahardjo N, Gay T, Banania JG, Chattopadhyay R, de la Vega P, Richie TL, Tornieporth N, Doolan DL, Kester KE, Heppner DG, Norman J, Carucci DJ, Cohen JD, Hoffman SL. 2004. Induction in humans of CD8+ and CD4+ T cell and antibody responses by sequential immunization with malaria DNA and recombinant protein. Journal of Immunology 172:561–569.

Wang R, Richie TL, Baraceros MF, Rahardjo N, Gay T, Banania JG, Charoenvit Y, Epstein JE, Luke T, Freilich DA, Norman J, Hoffman SL. 2005. Boosting of DNA vaccine-elicited gamma interferon responses in humans by exposure to malaria parasites. Infection and Immunity 73(5):2863–2872.

Webster DP, Dunachie S, Vuola JM, Berthoud T, Keating S, Laidlaw SM, McConkey SJ, Poulton I, Andrews L, Andersen RF, Bejon P, Butcher G, Sinden R, Skinner MA, Gilbert SC, Hill AV. 2005. Enhanced T cell-mediated protection against malaria in human challenges by using the recombinant poxviruses FP9 and modified vaccinia virus Ankara. Proceedings of the National Academy of Sciences USA 102(13):4836–4841.

Weiss WR, Sedegah M, Beaudoin RL, Miller LH, Good MF. 1988. CD8+ T cells (cytotoxic/ suppressors) are required for protection in mice immunized with malaria sporozoites. Proceedings of the National Academy of Sciences USA 85(2):573–576.

WHO (World Health Organization). 1986. Chemotherapy of Malaria. Geneva, Switzerland: World Health Organization.

WHO. 2002. The World Health Report 2002:Reducing Risks, Promoting Healthy Life. Geneva, Switzerland: World Health Organization.

WHO. 2005. Initiative for Vaccine Research. [Online]. Available: [Accessed 3 May 2006].

Zavala F, Tam JP, Hollingdale MR, Cochrane AH, Quakyi I, Nussenzweig RS, Nussenzweig V. 1985. Rationale for development of a synthetic vaccine against Plasmodium falciparum malaria. Science 228(4706):1436–1440.

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