. "Appendix A Vaccine Trials." Battling Malaria: Strengthening the U.S. Military Malaria Vaccine Program. Washington, DC: The National Academies Press, 2006.
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Battling Malaria: Strengthening the U.S. Military Malaria Vaccine Program
Erythrocytic Stage Vaccines
Peptide
MSP-3/alum or ISA 720
No
Antibody, T cells, interferon
Audran et al., 2005
Recombinant protein
MSP-1/MSP-2 conjugated to diphtheria toxoid
No
Good antibody response; hypersensitivity to diphtheria toxoid
Ramasamy et al., 1995
MSP-1/P30P2: two allelic forms of MSP119 plus tetanus toxoid T-cell epitopes
WRAIR
Good antibody response in 14/32
Keitel et al., 1999
AMA-1C (3D7 and FVO forms), Pichia pastoris expressed
