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PAPERBACK price:$35.00 add to cart Rights & Permissions Free PDF Access Sign in to download PDF book and chapters Free Resources PDF SUMMARY Display this book on your site! Related Titles Saving Lives, Buying Time: Economics of Malaria Drugs in an Age of Resistance Malaria: Obstacles and Opportunities Other Related Titles Battling Malaria: Strengthening the U.S. Military Malaria Vaccine Program (2006) Medical Follow-Up Agency (MFUA) Citation Manager Export the bibliographic data for this book in your chosen format Web Search Builder Use this book's key terms to search within this book, across our collection, or across the Web. Skim This Chapter Skim this chapter and use this chapter's key terms to search within this book. Reference Finder Paste in your own text to find books that relate to your topic. Citation Manager . "Appendix B Current Requirements for a Malaria Vaccine." Battling Malaria: Strengthening the U.S. Military Malaria Vaccine Program. Washington, DC: The National Academies Press, 2006. Please select a format: Page 95   E-mail Share on facebook Facebook Share on delicious Delicious Share on stumbleupon Stumble Share on twitter Twitter More Sharing ServicesMore The following HTML text is provided to enhance online readability. Many aspects of typography translate only awkwardly to HTML. Please use the page image as the authoritative form to ensure accuracy. Appendix B Current Requirements for a Malaria Vaccine The current requirements for a Plasmodium falciparum vaccine are formulated in a U.S. Army Operational Requirements Document (ORD) dated March 13, 1997, which has now expired and will be replaced by a Capability Development Document (CDD) that is currently (January 2006) in draft. Although these documents have been prepared under the auspices of the U.S. Army, the requirements are no different for the Navy and Marines. The table below shows the requirements as they stand in the expired ORD and the draft CDD. TABLE B-1 Current Operational Requirements for a P. falciparum Malaria Vaccine Attribute Development Threshold Development Objective Efficacy 80% protection 90% protection Time to protection Within 14 days Within 7 days Duration of protection At least 1 year At least 2 years Shelf life At least 2 years At least 3 years Dosing schedule Protection will be attained after two doses Protection will be attained after one dose Page 95 Front Matter (R1-R22) Summary (1-8) 1 Introduction (9-12) 2 The Malaria Threat and Need for a Vaccine (13-20) 3 Malaria Vaccines (21-40) 4 The U.S. Military Malaria Vaccine Research and Development Program--Scientific Aspects (41-55) 5 Organization and Management of the Program (56-70) References (71-80) Appendix A Vaccine Trials (81-94) Appendix B Current Requirements for a Malaria Vaccine (95-95) Appendix C Suggested Design of Trials for Testing Malaria Vaccines in Nonimmune Adults Visiting Endemic Areas (96-98) Appendix D Patents (99-101) Appendix E Scientific Advisory Board for DoD Malaria Vaccine Research and Development Program (Draft Charter) (102-104) Appendix F Recommendations of the IOM Report Protecting Our Forces (105-106) Appendix G Executive Summary and Recommendations of the DoD Report Acquisition of Vaccine Production (107-109) Appendix H Open Meeting Agenda (110-114) Appendix I Committee and Staff Biographies (115-122)

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Battling Malaria: Strengthening the U.S. Military Malaria Vaccine Program Appendix B Current Requirements for a Malaria Vaccine The current requirements for a Plasmodium falciparum vaccine are formulated in a U.S. Army Operational Requirements Document (ORD) dated March 13, 1997, which has now expired and will be replaced by a Capability Development Document (CDD) that is currently (January 2006) in draft. Although these documents have been prepared under the auspices of the U.S. Army, the requirements are no different for the Navy and Marines. The table below shows the requirements as they stand in the expired ORD and the draft CDD. TABLE B-1 Current Operational Requirements for a P. falciparum Malaria Vaccine Attribute Development Threshold Development Objective Efficacy 80% protection 90% protection Time to protection Within 14 days Within 7 days Duration of protection At least 1 year At least 2 years Shelf life At least 2 years At least 3 years Dosing schedule Protection will be attained after two doses Protection will be attained after one dose

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