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Asbestos: Selected Cancers (2006)
Board on Population Health and Public Health Practice (BPH)

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. "APPENDIX B Lineage and Design Properties of Studies on Cohorts Informative for Selected Cancers." Asbestos: Selected Cancers. Washington, DC: The National Academies Press, 2006.

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Asbestos: Selected Cancers

APPENDIX B
Lineage and Design Properties of Studies on Cohorts Informative for Selected Cancers

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Asbestos: Selected Cancers APPENDIX B Lineage and Design Properties of Studies on Cohorts Informative for Selected Cancers

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Asbestos: Selected Cancers TABLE B.1 Lineage and Design Properties of Studies on Cohorts Informative for Selected Cancers Cohort Population (location—number, description) Type of Exposure Number of Workersa Patients with Asbestos-Related Disease     Italy— implied high exposure to asbestos 276 textile workers 631 women compensated for asbestosis 278 asbestos cement workers mainly chrysotile   mainly crocidolite   Finland—     1,376 asbestosis patients     4,887 patients with pleural disease     Poland—     907 men with asbestosis     490 women with asbestosis     US clinical trial monitoring asbestos-exposed men men with asbestos exposure in clinical trial of lung cancer prevention 1,839 asbestos-exposed (smoking-eligible) vs 7,924 heavy smokers (not asbestos-exposed) Mining     Wittenoom Gorge, Western Australia crocidolite 6,000 men     6,505 men 411 women     6,506 men     6,493 men 415 women     ~5,700 men alive in 1980

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Asbestos: Selected Cancers Temporal Definition Follow-Up Citationb alive and on asbestosis compensation roles 12/31/1979 1/1/1980-10/30/1997 Germani et al. (1999) 1964-1995 1967-1995 Karjalainen et al. (1999) diagnosed 1970-1997 1999 Szeszenia-Dabrowska et al. (2002)   prospective for 10-18 yrs (1984-2004) Aliyu et al. (2005) 1943-1966   Hobbs et al. (1980) 1943-1966 1980 Armstrong et al. (1988) 1943-1966 1980 de Klerk et al. (1989) 1943-1966 2000 Berry et al. (2004) 1943-1966 1979-2000 Reid et al. (2004)

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Asbestos: Selected Cancers Cohort Population (location—number, description) Type of Exposure Number of Workersa Quebec, Canada—Asbestos and Thetford Mines chrysotile 6,091 male miners     11,788 men and women     544   chrysotile, also exposed to crocidolite workers at factory in Asbestos, Quebec     10,939 men 440 women     10,939 men 440 women     5,351 men surviving through 1976 of original 10,939 men     10,918 men Finland—Paakkila and Maljasalmi Mines anthophyllite 1,092   anthophyllite 1,092   anthophyllite 736 men, 167 women Balangero, Italy chrysotile 932   chrysotile 1,094 Northern Transvaal, South Africa—North West Cape Blue and Penge Mines crocilodite 7,317 white men amosite 3,430     3,212     675 both Libby, MT, US— NIOSH sample tremolite-actinolite     tremolite-actinolite 575 men   tremolite 1. 569 men 2. 406 men

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Asbestos: Selected Cancers Temporal Definition Follow-Up Citationb employed in 1950, ≥ 5 yrs exposure 1955 Braun and Truan (1958) born 1881-1920; with >1 mo working 11/1/1966 McDonald et al. (1971) employees with ≥ 20 yr in 1961 1977 Nicholson et al. (1979) born 1881-1920; with >1 mo working 1975 McDonald and Liddell (1979) born 1881-1920; with >1 mo working 1975 McDonald et al. (1980) born 1891-1920; with >1 mo before 1967 1975 Liddell et al. (1984) born 1891-1920; with >1 mo working 1976-1988 McDonald et al. (1993) born 1891-1920; with >1 mo working 1992 Liddell et al. (1997) 1/1/1936-6/30/1967, ≥ 3 mo 5/201969 Meurman et al. (1974) 1/1/1936-6/30/1967, ≥ 3 mo 9/1/1977 Meurman et al. (1979) worked ≥ 3 mo 1/1/1936-6/30/1967; alive 1/1/1953 1953-1991 Meurman et al. (1994) > 1 mo 1930-1965; alive 1/1/1946 1946-1975 Rubino et al. (1979) 1946-1987, > 1 yr 1987 Piolatto et al. (1990) 1945-1955 1980 Sluis-Cremer et al. (1992)     Amandus et al. (1987) pre-1970; > 1 yr 1981 Amandus and Wheeler (1987) 1. pre-1970; > 1 yr 2. pre-1963; > 1 yr 1. 1981 2. June 1983 Amandus et al. (1988)

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Asbestos: Selected Cancers Cohort Population (location—number, description) Type of Exposure Number of Workersa Insulation Manufacture / Insulators Canada/USA   632 men     632 men     17,800 men (including survivors of 1 and 2) 632 male insulation workers before 1943 in NY/NJ   632 men     833 men     17,800 men     17,800 men     17,800 men Paterson, NJ, US— 820 men producing amosite asbestos insulation for shipbuilding amosite 820 men   amosite 820 men     17,800 men 17,800 male members in 1967 of asbestos insulation unions   17,800 men Uxbridge, UK—Cape [insulation] Boards Plant amosite 4,820 male asbestos workers   amosite 4,825 men   1947-1973 amosite and small amt chrysotile; 1973 only amosite autopsies on 48 workers East London, UK—1,400 male laggers [subgroups 1 and 2 make up population 32] crocidolite, amosite and chrysotile ~3,000 male factory workers     ~700 female factory     ~1,400 laggers (insulators) Tyler, TX, US—753 white male asbestos pipe-insulation plant workers amosite 753 white men

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Asbestos: Selected Cancers Temporal Definition Follow-Up Citationb 1. members < 1943 1943-1962 Selikoff et al. (1964) 1. members < 1943 1. 1943-1971 Selikoff (1974) 3. in union 1/1/1967 3. 1967-1971   1. members < 1943 1. 1943-1976 Selikoff et al. (1979) 2. joined 1943-1962 2. hire date—1976   3. in union 1/1/1967 3. 1967-1976   in union 1/1/1967 1967-1976 Selikoff et al. (1980) in union 1/1/1967 1967-1979 Seidman et al. (1982) 1941-1945 1985 Seidman et al. (1986) 1941-1945 1988 Ribak et al. (1989) in union 1/1/1967 1967-1986 Seidman and Selikoff (1990) in union 1/1/1967 1967-1986 Selikoff and Seidman (1991) 1947-1979 1947-1980 Acheson et al. (1984) 1947-1979 1986 Gardner et al. (1988)     Gibbs et al. (1994) 1 and 3. began 4/1/1933-3/31/1964, 1980 Berry et al. (2000) > 1 mo     2. began 1936-1942 workers     worked at plant during operation (1954-1972) or during clean-up; alive in 1964 1964-1993 Levin et al. (1998)

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Asbestos: Selected Cancers Cohort Population (location—number, description) Type of Exposure Number of Workersa Asbestos Textile Workers     Italy—889 male and 1,077 female textile workers   889 men, 1,077 women Rochdale, Northern England asbestos (textile) workers chrysotile 1°, crocidolite   asbestos textiles chrysotile 1°, crocidolite   asbestos workers     asbestos textiles chrysotile 1°, crocidolite   asbestos textiles chrysotile, crocidolite   chrysotile, crocidolite 3,222 men and 283 women Charleston, SC, USA— asbestos textile workers chrysotile     chrysotile     chrysotile 1,261 white men   chrysotile 1,261 men   chrysotile only 2,543 men (black and white, reason so much larger?)   chrysotile 3,022 subjects;     1,247 white men     546 black men     1,229 white women   chrysotile 3,022 subjects;     1,247 white men     546 black men     1,229 white women

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Asbestos: Selected Cancers Temporal Definition Follow-Up Citationb 1946-1984, ≥ 1 mo 1996 Pira et al. (2005) 113 men > 20 yr completed 1922-1953 Doll (1955) 1. 198 men 1. > 20 yr completed 1916-1961 Knox et al. (1965) 2. 427 men and 175 women 2. > 10 yr expo; hired > 1932   113 men   Hill et al. (1966) 878: 658 men and 220 women 1916-1966, > 10 yrs Knox et al. (1968) 1,106 1916-1972 Peto et al. (1977) 1916-1983 6/30/1983 Peto et al. (1985)     Dement et al. (1982) 1930-1975   Dement et al. (1983a) 1940-1975, > 1 mo 1975 Dement et al. (1983b) 1940-1975 1975 Finkelstein (1984) > 1 mo working before 1958 1977 McDonald et al. (1983) 1940-1975 1990 Brown et al. (1994) 1940-1975 1990 Dement et al. (1994)

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Asbestos: Selected Cancers Cohort Population (location—number, description) Type of Exposure Number of Workersa Asbestos Cement     Denmark—Danish Eternit Ltd. cement factory chrysotile, crocidolite and amosite 5,686 men   chrysotile mostly (only < 1946), amosite, crocilodite 7,979 men 583 women   mainly chrysotile; amosite, crocilodite 7,887 men 576 women     7,887 men, 576 women Emilia Romagna, Italy— 10 cement factories chrysotile, crocidolite 3,341 Casale Monferrato, Italy —asbestos cement production crocidolite and chrysotile 2,608 men 759 women   chrysotile, crocidolite 2,605 men 762 woman Lithuainia—Daugeliai and Akmene Factories chrysotile—almost only 1,285 men 602 women Southern Sweden— asbestos cement plant       >95% chrysotile; crocidolite and amosite 1,929 men     981 male asbestos cement workers Tamworth, England, UK—TAC Construction Materials Ltd. chrysotile—almost only 1,510 men 657 women New Orleans, LA, US—workers at two asbestos cement plants primarily chrysotile,     some crocidolite and amosite 1,898 men at plant 1   crocidolite 3,594 men at plant 2   chrysotile, amosite, crocidolite 839 men

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Asbestos: Selected Cancers Temporal Definition Follow-Up Citationb 1943-1976 1976 Clemmensen and Hjalgrim-Jensen (1981) ever 1928-1984; alive 1943 1943-1984 Raffn et al. (1989) 1928-1984 1943-1990 Raffn et al. (1996) 1928-1984 1943-1990 Raffn et al. (1998) 1952-1987 1989 Giaroli et al. (1994) worked anytime 1950-1980 1964-4/15/1986 Botta et al. (1991) worked anytime 1950-1980 1965-1993 Magnani et al. (1996) pre-1978 2000 Smailyte et al. (2004a) 1907- 1985 Albin et al. (1988) 1907-1977 1986 Albin et al. (1990) > 1 yr employed; 15 yrs latency 1958-1989 Jakobsson et al. (1994) 1941-1983 1984 Gardner et al. (1986) employed before 1970; 20 yr latency Oct 1980 Hughes et al. (1987) had clinical exam in 1969 with x-ray 1983 Hughes and Weill (1991)

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Asbestos: Selected Cancers Cohort Population (location—number, description) Type of Exposure Number of Workersa Friction Materials     Ontario, Canada—two automotive parts factories   1,314 men 343 women Ferodo, UK—friction materials factory crocidolite, chrysolite 9,113 men 4,347 women   chrysotile; some crocidolite <1945 13,460   crocidolite, chrysolite 9,104 men 4,346 women   chrysotile 9,104 men 4,346 women USSR chrysotile 156     2,834 New York, US—friction products manufacture chrysotile 2,057 men     268 men 54 women Generic “Asbestos Workers”     China—eight asbestos factories chrysotile 5,893 men and women Qingdao, China—asbestos plant chrysotile 160 men 370 women Federal Republic of Germany—asbestos- related workers from national register (smoking info) 3,735 men and women     665 exposure ended <1972     3,070 exposure ended >1971     616 women     3,372 men 616 women

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Asbestos: Selected Cancers Temporal Definition Follow-Up Citationb 1/1/1950; > 1 yr 1985 Finkelstein (1989a) 1941-1979 1979 Newhouse et al. (1982) 1942-1979 1979 Berry and Newhouse (1983) 1941-1979 1986 Newhouse and Sullivan (1989) 1941-1986 1986 Berry (1994) 1. working in FP shop 1/1/1966 1. 1984 Kogan et al. (1993) 2. Yoroslavl plant, > 3yr 2. 1949-1988   1. ? 1. 1937-1980 Parnes (1990) 2. current employees     worked > 15 yr 1986 Zhu and Wang (1993) pre-1972; > 1 yr 1994 Pang et al. (1997) > 3 yrs expo before1977 1977-1982 Woitowitz et al. (1986) > 3 yrs expo before 1977 1977-1988 Rosler et al. (1994)   1977-1988? Rosler and Woitowitz (1995)

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Asbestos: Selected Cancers Cohort Population (location—number, description) Type of Exposure Number of Workersa East London, UK—3000 male and 700 female asbestos factory workers [subgroup 3 makes up population 13] crocidolite, small amount chrysotile, amosite after 1926 4,835 men 922 women after limit cohort to enhance tracking   crocidolite, amosite and chrysotile >4,000 workers 1,327 severe expo   crocidolite, amosite and chrysotile 3,232 male factory workers   922 female factory workers     1,368 male laggers   crocidolite, amosite and chrysotile ~3,000 male factory workers     932 female factory workers     ~1,400 laggers   crocidolite, amosite and chrysotile ~3,000 male factory workers     932 female factory workers     ~1,400 laggers Lancashire, UK—gas mask manufacture chrysotile and crocidolite 1,327 women England and Wales, UK— national survey of asbestos workers various types of asbestos 31,150 men traced and examined of 33,079 total US—asbestos industry retirees production or maintenance service employees for asbestos company 1,464 men     1,348 men 65 yr old; full expo and job history   amosite, chrysotile, crocidolite 1,348 men   amosite, chrysotile, crocidolite 1,075 men of above who worked in US   amosite, chrysotile, crocidolite 1,074 men

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Asbestos: Selected Cancers Temporal Definition Follow-Up Citationb worked 4/1/1933-3/31/1964, > 1 mo began 1936-1942 5/1/1965 1968 Newhouse (1969) Newhouse et al. (1972) worked 4/1/1933-3/31/1964, > 1 mo   Newhouse and Berry (1973) 1 and 3. began 4/1/1933-3/31/1964 1975 Newhouse and Berry (1979) 2. began 1936-1942   1 and 3. began 4/1/1933-3/31/1964 1980 Newhouse et al. (1985b) 2. began 1936-1942     1 and 3. began 4/1/1933-3/31/1964, 1980 Berry et al. (2000) > 1 mo     2. began 1936-1942     1939 1951-1980 Acheson et al. (1982) asbestos work first before 1969 or only after 1969 (max 12 yr latency) 1981 Hodgson and Jones (1986) retired 1941-1967 1969 Enterline et al. (1972) 1941-1967 1969 Enterline et al. (1973) 1941-1967 1969 Enterline and Henderson (1973) 1941-1967 1973 Henderson and Enterline (1979) 1941-1967 1980 Enterline et al. (1987)

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Asbestos: Selected Cancers Cohort Population (location—number, description) Type of Exposure Number of Workersa Other Occupations with Substantial Asbestos Exposure Ontario, Canada— members of plumbers’ and pipe fitters’ union   25,285 men Finland—7,775 male shipyard workers asbestos one of many toxic exposures 12,693 men: 1,689 welders, 4,308 platers, 6,003 machinists, 693 pipe fitters (608 in shipyard) Tuscany, Italy—railway carriage construction and repair chrysotile, crocidolite 734 men Genoa, Italy—ship repair, refitting, and construction asbestos one of many toxic exposures 2,348 men   asbestos one of many toxic exposures 2,190 men   asbestos one of many toxic exposures 3,984 men Gothenburg, Sweden— shipyard workers shipyards sprayed mostly amosite; crocidolite used on 4 naval ships in 1950s 272 men   shipyard insulation workers 248   asbestos and other potenially toxic agents (metal fumes and solvents) 383 men (18 not fully IDed)   handled chrysotile (around spraying of amosite, some crocidolite); asbestos use stopped in 1972 3,902 participated in health program 1977-1979 (self-selected for belief ever exposed to asbestos)   chrysotile, mainly 3,893 aNumber of subjects with information necessary for analysis (as used in this report’s meta-analyses and reported in tables in Appendix D) may have been less. bFull citations can be found in the reference list for Chapter 6.

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Asbestos: Selected Cancers Temporal Definition Follow-Up Citationb 1950-1999 1999 Finkelstein and Verma (2004) 1945-1960, > 1 yr 1953-1981 Tola et al. (1988) [incidence] 1945-1969 1970-1997 Battista et al. (1999) worked any time before 1952; alive 1960 1960-1969 Puntoni et al. (1977) worked any time 1960-1970 1960-1975 Puntoni et al. (1979) worked any time 1960-1980 1960-1995 Puntoni et al. (2001) active in union 1970 1970-1979 Sanden et al. (1984)   1970-1994 Jarvholm and Sanden (1988) insured worker dying 1960-1979 at 40-67 yrs of age   Sanden et al. (1985)   1978-1983 Sanden and Jarvholm (1987) [incidence]     Sanden et al. (1992)

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Representative terms from entire chapter:

con ession