APPENDIX A
Forum on Microbial Threats

Board on Global Health

Institute of Medicine

The National Academies


Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship


March 16–March 17, 2005

KECK 100

National Academies

500 Fifth Street, N.W.

Washington, D.C. 20001


AGENDA

WEDNESDAY, MARCH 16, 2005

8:30–9:00

Continental Breakfast

9:00

Welcome and Opening Remarks

 

Stanley Lemon, The University of Texas Medical Branch, Galveston; Chair, Forum on Microbial Threats



The National Academies | 500 Fifth St. N.W. | Washington, D.C. 20001
Copyright © National Academy of Sciences. All rights reserved.
Terms of Use and Privacy Statement



Below are the first 10 and last 10 pages of uncorrected machine-read text (when available) of this chapter, followed by the top 30 algorithmically extracted key phrases from the chapter as a whole.
Intended to provide our own search engines and external engines with highly rich, chapter-representative searchable text on the opening pages of each chapter. Because it is UNCORRECTED material, please consider the following text as a useful but insufficient proxy for the authoritative book pages.

Do not use for reproduction, copying, pasting, or reading; exclusively for search engines.

OCR for page 261
Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship - Workshop Summary APPENDIX A Forum on Microbial Threats Board on Global Health Institute of Medicine The National Academies Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship March 16–March 17, 2005 KECK 100 National Academies 500 Fifth Street, N.W. Washington, D.C. 20001 AGENDA WEDNESDAY, MARCH 16, 2005 8:30–9:00 Continental Breakfast 9:00 Welcome and Opening Remarks   Stanley Lemon, The University of Texas Medical Branch, Galveston; Chair, Forum on Microbial Threats

OCR for page 261
Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship - Workshop Summary 9:15 Arms Races with Evolving Diseases: “We’ve Met the Enemy and He Is Us”   Joshua Lederberg, Rockefeller University Stanley Falkow, Stanford University 10:15 Discussion 10:30 Break Session I: Host-Pathogen Interactions: Defining the Concepts of Pathogenicity, Virulence, Colonization, Commensalism, and Symbiosis Moderator: P. Frederick Sparling, University of North Carolina Vice-chair, Forum on Microbial Threats 10:45 Colonization   Jeffrey I. Gordon, Washington University School of Medicine, or, Karen Guillemin, University of Washington 11:45 Discussion 12:15 Lunch—Welcoming Remarks by Dr. Harvey Fineberg, President, Institute of Medicine 1:00–2:30 Commensalism and Symbiosis—Host, Microbial, and Environmental Factors   Abigail Salyers, University of Illinois, Champaign-Urbana Jo Handelsman, Department of Plant Pathology, University of Wisconsin, Madison 2:30–2:45 Discussion 2:45–3:00 Break 3:00–4:15 Pathogenicity and Virulence   Martin Blaser, New York University School of Medicine BJ Staskawicz, University of California, Berkeley 4:15–5:45 Open Discussion of Day 1 Moderator: David Relman, Stanford University   Balfor Sartor, University of North Carolina Maria G. Dominguez-Bello, University of Puerto Rico, Rio Piedras 5:45 Adjournment of the first day

OCR for page 261
Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship - Workshop Summary 6:00 Reception 7:15 Dinner Meeting of the Forum on Microbial Threats [location TBD] THURSDAY, MARCH 17, 2005 8:00–8:30 Continental Breakfast 8:30 Opening Remarks/Summary of Day 1   P. Frederick Sparling, University of North Carolina Vice-chair, Forum on Microbial Threats Session II: Ecology of Host-Microbe Interactions   Moderator: Stephen S. Morse, Columbia University 8:40–9:25 Endogenous Microbial Communities   David Stahl, University of Washington Mark E.J. Woolhouse, Centre for Tropical Veterinary Medicine, University of Edinburgh 9:25–10:15 How the Host “Sees” and Responds to Pathogens   Marian Neutra, Harvard Medical School and Children’s Hospital David Relman, Stanford University 10:15–10:30 Discussion 10:30–10:45 Break Session III: Understanding the Dynamic Relationships of Host-Microbe Interactions—Discussion Panel Moderator: David Relman, Stanford University 10:45–12:15 Lonnie King, Michigan State University Stanley Falkow, Stanford University Jeffrey I. Gordon, Washington University School of Medicine 12:15–12:45 Lunch

OCR for page 261
Ending the War Metaphor: The Changing Agenda for Unraveling the Host-Microbe Relationship - Workshop Summary Session IV: Novel Approaches for Mitigating the Development of Resistance Moderator: James Hughes, Emory University 12:45–1:30 Using Pre- and Probiotics to Modify Host-Environmental Factors to Promote Health and Mitigate Disease   Michiel Kleerebezem, Holland Suzanne Cunningham-Rundles, Cornell University 1:30–2:00 Governmental Approaches to Regulating Pre- and Probiotics   Lorenzo Morelli, Istituto di Microbiologia UCSC—Italy Julienne Vaillancourt, CBER, FDA 2:00–2:15 Discussion Session V: Challenges and Opportunities to Developing a New Paradigm to Replace the “War Metaphor” Moderator: Fredrick Sparling, University of North Carolina, Chapel Hill 2:15–4:00 With the backdrop of the previous days’ presentations and discussion, Forum members, panel discussants, and the audience will comment on the issues and next steps that they would identify as priority areas for consideration within industry, academia, public health organizations, and other government sectors. The discussion of priorities will summarize the issues surrounding emerging opportunities for more effective collaboration as well as the remaining research and programmatic needs. The confounding issues of the major obstacles to preparing an optimal response, particularly as it relates to the complexities of interaction between private industry, research and public health agencies, regulatory agencies, policy makers, academic researchers, and the public, will be explored with an eye toward innovative responses to such challenges. Panel Discussants:   Joshua Lederberg, Rockefeller University David Stahl, University of Washington 4:00 Adjourn