Studies designed to learn more about mechanisms and modes of action in the presence of the most commonly occurring toxicants are likely to yield the most meaningful results.
Testing to evaluate the impact of lifestyle factors, such as alcohol consumption, smoking, chronic drug intake, and diet (e.g., nutrition, caloric restriction) should be performed.
Testing of mixtures to evaluate the impact of disease (e.g., diabetes) and special physiologic states (e.g., pregnancy, aging) should be performed.
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10 Mixtures ."
Assessing the Human Health Risks of Trichloroethylene: Key Scientific Issues . Washington, DC: The National Academies Press,
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