Amount

Results

Conclusion*

Semipurified diet:

Deficient in n-3 fatty acids

Safflower oil was sole fat source

High n-6:n-3 ratio

Controls:

Soybean oil was sole fat source

High in LA

At all ages, animals of the “deficient group had considerably lower levels of n-3 fatty acids in tissue phospholipids than their controls.”

Based on the occipital cortex, perinatal 22:5n-6 (p<0.01) and total n-6 (p<0.05) were significantly higher and perinatal DHA (p<0.01) and total n-3 (p<0.01) were significantly lower in the deficient group compared to the control group.

Based on the occipital cortex, 22:4n-6 (p<0.01), 22:5n-6 (p<0.01), and total n-6 (p<0.01) at 22 months were significantly higher and DHA (p<0.01) and total n-3 (p<0.01) at 22 months were significantly lower in the deficient group compared to the control group.

Based on the frontal cortex, perinatal 22:5n-6 (p<0.01) was significantly higher and perinatal DHA (p<0.01) and total n-3 (p<0.01) were significantly lower in the deficient group compared to the control group.

Based on the frontal cortex, 22:5n-6 (p<0.01) and total n-6 (p<0.01) at 22 months were significant higher and DHA (p<0.01) and total n-3 (p<0.01) at 22 months were significantly lower in the deficient group compared to the control group.

N/A



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