Amount

Results

Conclusion*

Breast milk (% total fatty acids, mean±SE):

LA = 6.90±0.81, ALA = 0.80±0.05, EPA = 0.20±0.08, DPA = 0.52±0.27, DHA = 0.59±0.23

Milk formula (% total fatty acids, mean):

LA = 1.60, ALA = 0.70, EPA = 0.08, DPA = 0.11, DHA = 0.02

LA, AA, DHA are significantly lower in the formula-fed infants than in the breast-fed infants (p<0.01, p<0.05, p<0.01, respectively).

EPA and DPA are significantly higher in the formula-fed infants than in the breast-fed infants (p<0.05).

“The minimum requirement of the young infant for LA is substantially less than 1% of the dietary energy, the value most widely quoted.”

N/A

Experimental group:

Semipurified diet deficient in n-3 fatty acids

Safflower oil sole fat source

76.0% LA, 0.3% GLA, 0.2% DGLA, 0.3% ALA, 225.0% n-6:n-3 of total fatty acids

Control group:

Soy bean oil sole fat source

53.1% LA, 0.0% GLA, 0.3% DGLA, 7.7% ALA, 7.0% n-6:n-3 of total fatty acids

AA and total n-6 fatty acids were significantly higher in the experimental group infants compared to the control group infants (p<0.005).

ALA, EPA, DPA, DHA and total n-3 fatty acids are all significantly lower in the experimental group infants compared to the control group infants (p<0.001).

At 4, 8, and 12 weeks, the visual acuity threshold in the experimental group was significantly lower than in the control group (p<0.05, p<0.0005, p<0.005, respectively).

B



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