Intervention group:

500 mg/day tuna fish oil

184 mg omega-3 fatty acids

Placebo group:

Sunola oil

83% monounsaturated oil

At 3 years of age, there were no significant differences in prevalence of asthma, wheezing, eczema, and atopy between the intervention group and the placebo group. However, those in the intervention group had significantly lower prevalence of mild or moderate coughing (p=0.03) and atopic coughing (p=0.003) than the placebo group.


Omega-3 group:

0.18 g EPA and 0.12 g DHA/capsule

4 capsules/day = 1.2 g omega-3/day

Omega-6 group:

0.45 g safflower oil, 0.45 g palm oil, 0.10 g olive oil/capsule


“There was no significant change in spirometric function, dose response ratio to histamine or asthma severity score at either 3 or 6 months in either group.”

“There were no significant differences between groups in TNFα production over time (p=0.22).”

“Dietary enrichment of omega-3 fatty acids over 6 months increased plasma levels of these fatty acids, reduced stimulated tumour necrosis factor α production, but had no effect on the clinical severity of asthma in these children.”


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