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High omega-3 fat vs. low omega-3 fat/control
Intake differed by 0.1-0.6 g omega-3/day among the two groups (absolute levels not specified)
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Based on RCTs, no significant differences were found between the high omega-3 fat group and the low omega-3 fat/control group with regards to risk of mortality (n=15 RCTs; RR=0.87, 95% CI 0.73-1.03), cardiovascular events (n=18 RCTs; RR=0.95, 95% CI 0.82-1.12), cancer or death from cancer (n=10 RCTs; RR=1.07, 95% CI 0.88-1.30), or stroke (n=9 RCTs; RR=1.17, 95% CI 0.91-1.51).
Based on cohorts, no significant differences were found between the high omega-3 fat group and the low omega-3 fat/control group with regards to risk of cardiovascular events (n=7 cohorts; RR=0.91, 95% CI 0.73-1.13), cancer or death from cancer (n=7 cohorts; RR=1.02, 95% CI 0.87-1.19), or stroke (n=4 cohorts; RR=0.87, 95% CI 0.72-1.04).
Based on three cohorts, those in the low omega-3 fat/control group had a significantly higher risk of mortality compared to those in the high omega-3 fat group (RR=0.65, 95% CI 0.48-0.88).
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N
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