Study Type



Vericel et al., 1999

Randomized Controlled Trial

Men and women (n=20)

Aged 70-83 years


Diastolic blood pressure <95 mmHg and systolic blood pressure <180 mmHg

No metabolic, malignant, or degenerative diseases

Follow-up of 42 days

n-3 supplement

Leng et al., 1998*

Randomized Controlled Trial

Men and women (n=120)

Mean age about 66 years

Edinburgh, UK

Intermittent claudication on the Edinburgh Claudication Questionnaire

An ankle brachial pressure index ≤0.9 in at least one limb

No clinical evidence of critical ischemia; unstable angina or a MI within the previous 3 months; severe intercurrent illnesses including severe liver disorders, malignancy, or epilepsy; concurrent treatment with anticoagulants, other oils, lithium, or phemothiazines; pregnant or actively trying to conceive; already participating in a clinical trial

Follow-up of 2 years

n-3 supplement

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