Potential Long-Term Outcomes in Adults with Clinical Disease

Disease or Syndrome

Acute Syndrome(s) in Adults

Disease(s), Syndrome(s), or Clinical Features

Frequency of Occurrence of Outcomesa

Delay Between Acute Infection and Onset of Outcomesb

Staphylococcus infection

Focal infections, pneumonia, bacteremia

Sepsis or infection-related organ damage

Rare

No

Streptococcus infection

Pharyngitis, bacteremia, pneumonia, focal infections

Sepsis or infection-related organ damage

Rare

No

Glomerulonephritis

Very rare

No

Rheumatic fever

Very rare

No

Streptococcus pneumoniae infection

Respiratory tract infection, meningitis, bacteremia, sepsis

Sepsis or infection-related organ damage

Rare

No

Antibiotic-resistant or common nosocomial bacterial infections

Acinetobacter infectionc

(multiple-drug-resistant)

Skin and soft-tissue infections, abscesses, pneumonia, bacteremia, urinary tract infections

Sepsis or infection-related organ damage

Rare

No

Enterococcus infection

(vancomycin resistant)

Skin and soft-tissue infections, abscesses, bacteremia, urinary tract infections

Sepsis or infection-related organ damage, endocarditis

Rare

No

Klebsiella infection (multiple-drug-resistant)

Skin and soft-tissue infections, abscesses, pneumonia, bacteremia, urinary tract infections

Sepsis or infection-related organ damage

Rare

No

Pseudomonas aeruginosa infection

Skin and soft-tissue infections, abscesses, pneumonia, bacteremia, urinary tract infections

Sepsis or infection-related organ damage

Rare

No

Staphylococcus aureus infection (methicillin-resistant)

Skin and soft-tissue infections, abscesses, pneumonia, bacteremia

Sepsis or infection-related organ damage, endocarditis

Rare

No

Osteomyelitis

Rare

Yes (months)

Stenotrophomonas maltophilia infection

Respiratory tract infection, bacteremia

Sepsis or infection-related organ damage

Very rare

No



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